{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,8]],"date-time":"2026-05-08T11:06:02Z","timestamp":1778238362222,"version":"3.51.4"},"reference-count":17,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Parasitology Research"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>This study investigated the biological activities of five benthic marine algae collected from Northeastern Region of Brazil. The tested activities included larvicidal activity against<jats:italic>Aedes aegypti<\/jats:italic>, molluscicidal activity against<jats:italic>Biomphalaria glabrata,<\/jats:italic>and toxicity against<jats:italic>Artemia salina<\/jats:italic>. Extracts of<jats:italic>Ulva lactuca<\/jats:italic>(Chlorophyta),<jats:italic>Padina gymnospora, Sargassum vulgare<\/jats:italic>(Phaeophyta),<jats:italic>Hypnea musciformis,<\/jats:italic>and<jats:italic>Digenea simplex<\/jats:italic>(Rhodophyta) were prepared using different solvents of increasing polarity, including dichloromethane, methanol, ethanol, and water. Of the extracts screened, the dichloromethane extracts of<jats:italic>H. musciformis<\/jats:italic>and<jats:italic>P. gymnospora<\/jats:italic>exhibited the highest activities and were subjected to bioassay-guided fractionation in hexane and chloroform. The chloroform fractions of the<jats:italic>P. gymnospora<\/jats:italic>and<jats:italic>H. musciformis<\/jats:italic>extracts showed molluscicidal activity at values below 40\u2009<jats:italic>\u03bc<\/jats:italic>g\u00b7mL<jats:sup>\u22121<\/jats:sup>(11.1460\u2009<jats:italic>\u03bc<\/jats:italic>g\u00b7mL<jats:sup>\u22121<\/jats:sup>and 25.8689\u2009<jats:italic>\u03bc<\/jats:italic>g\u00b7mL<jats:sup>\u22121<\/jats:sup>, resp.), and the chloroform and hexane fractions of<jats:italic>P. gymnospora<\/jats:italic>showed larvicidal activity at values below 40\u2009<jats:italic>\u03bc<\/jats:italic>g\u00b7mL<jats:sup>\u22121<\/jats:sup>(29.018\u2009<jats:italic>\u03bc<\/jats:italic>g\u00b7mL<jats:sup>\u22121<\/jats:sup>and 17.230\u2009<jats:italic>\u03bc<\/jats:italic>g\u00b7mL<jats:sup>\u22121<\/jats:sup>, resp.). The crude extracts were not toxic to<jats:italic>A. salina<\/jats:italic>, whereas the chloroform and hexane fractions of<jats:italic>P. gymnospora<\/jats:italic>(788.277\u2009<jats:italic>\u03bc<\/jats:italic>g\u00b7mL<jats:sup>\u22121<\/jats:sup>and 706.990\u2009<jats:italic>\u03bc<\/jats:italic>g\u00b7mL<jats:sup>\u22121<\/jats:sup>) showed moderate toxicity, indicating that the toxic compounds present in these algae are nonpolar.<\/jats:p>","DOI":"10.1155\/2014\/501328","type":"journal-article","created":{"date-parts":[[2014,2,13]],"date-time":"2014-02-13T21:03:33Z","timestamp":1392325413000},"page":"1-6","source":"Crossref","is-referenced-by-count":10,"title":["Larvicidal Activity against<i>Aedes aegypti<\/i>and Molluscicidal Activity against<i>Biomphalaria glabrata<\/i>of Brazilian Marine Algae"],"prefix":"10.1155","volume":"2014","author":[{"given":"El\u00edca Amara Cec\u00edlia","family":"Guedes","sequence":"first","affiliation":[{"name":"Laborat\u00f3rio de Produtos Naturais, Instituto de Qu\u00edmica e Biotecnologia, Universidade Federal de Alagoas, Campus A., C. Sim\u00f5es, Avenida Lourival Melo Mota, s\/n, Tabuleiro do Martins, 57072-970 Macei\u00f3, AL, Brazil"},{"name":"Universidade Federal de Alagoas, Icbs Campus A., C. Sim\u00f5es, Avenida Lourival Melo Mota, s\/n, Tabuleiro do Martins, 57072-970 Macei\u00f3, AL, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Cenira M. de","family":"Carvalho","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Produtos Naturais, Instituto de Qu\u00edmica e Biotecnologia, Universidade Federal de Alagoas, Campus A., C. Sim\u00f5es, Avenida Lourival Melo Mota, s\/n, Tabuleiro do Martins, 57072-970 Macei\u00f3, AL, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karlos Antonio Lisboa","family":"Ribeiro Junior","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Produtos Naturais, Instituto de Qu\u00edmica e Biotecnologia, Universidade Federal de Alagoas, Campus A., C. Sim\u00f5es, Avenida Lourival Melo Mota, s\/n, Tabuleiro do Martins, 57072-970 Macei\u00f3, AL, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thyago Fernando","family":"Lisboa Ribeiro","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Produtos Naturais, Instituto de Qu\u00edmica e Biotecnologia, Universidade Federal de Alagoas, Campus A., C. Sim\u00f5es, Avenida Lourival Melo Mota, s\/n, Tabuleiro do Martins, 57072-970 Macei\u00f3, AL, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lurdiana Dayse","family":"de Barros","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Produtos Naturais, Instituto de Qu\u00edmica e Biotecnologia, Universidade Federal de Alagoas, Campus A., C. Sim\u00f5es, Avenida Lourival Melo Mota, s\/n, Tabuleiro do Martins, 57072-970 Macei\u00f3, AL, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Raquel Ferreira","family":"de Lima","sequence":"additional","affiliation":[{"name":"Laborat\u00f3rio de Produtos Naturais, Instituto de Qu\u00edmica e Biotecnologia, Universidade Federal de Alagoas, Campus A., C. Sim\u00f5es, Avenida Lourival Melo Mota, s\/n, Tabuleiro do Martins, 57072-970 Macei\u00f3, AL, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fl\u00e1via de Barros","family":"Prado Moura","sequence":"additional","affiliation":[{"name":"Universidade Federal de Alagoas, Icbs Campus A., C. 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