{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,17]],"date-time":"2026-03-17T15:57:22Z","timestamp":1773763042468,"version":"3.50.1"},"reference-count":18,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Obstetrics and Gynecology"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Necrotizing fasciitis is a rare, life-threatening surgical infection in pregnancy with high rates of morbidity and mortality. A 15-year-old primigravid woman, at 28\u2009weeks of gestation with no significant previous medical history, was admitted to our hospital complaining of severe left lower extremity pain and high fever the last 72\u2009hours. During clinical examination, she had a swollen, erythematous and tender to palpation inflamed skin over the medial aspect of the upper thigh without any evidence of injury. Incision drainage was performed immediately and she received broad spectrum antibiotics. During initial laboratory examinations, diabetes mellitus was diagnosed. There was no clinical improvement over the following days. Magnetic resonance imaging (MRI) revealed subcutaneous tissue inflammation and edema of infected tissues confirming the disease entity. Multidisciplinary therapy with immediate aggressive surgical debridement of necrotic tissues, multiple antibiotics, and intensive care monitoring was performed successfully. The patient\u2019s postoperative course was uncomplicated and skin defect was closed with split thickness skin grafting. Our case emphasized the potential immunosuppressive role of pregnancy state in conjunction with diabetes mellitus in the development of severe necrotizing soft tissue infections.<\/jats:p>","DOI":"10.1155\/2014\/505410","type":"journal-article","created":{"date-parts":[[2014,3,9]],"date-time":"2014-03-09T17:01:21Z","timestamp":1394384481000},"page":"1-4","source":"Crossref","is-referenced-by-count":9,"title":["Necrotizing Fasciitis Complicating Pregnancy: A Case Report and Literature Review"],"prefix":"10.1155","volume":"2014","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9414-0634","authenticated-orcid":true,"given":"Marinos","family":"Nikolaou","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Medical School, University of Patras, Rio Achaia, 26500 Patras, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Petros","family":"Zampakis","sequence":"additional","affiliation":[{"name":"Department of Radiology, Medical School, University of Patras, 26500 Patras, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vasiliki","family":"Vervita","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Medical School, University of Patras, Rio Achaia, 26500 Patras, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Almaloglou","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Medical School, University of Patras, Rio Achaia, 26500 Patras, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios","family":"Adonakis","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Medical School, University of Patras, Rio Achaia, 26500 Patras, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Markos","family":"Marangos","sequence":"additional","affiliation":[{"name":"Department of Internal Medicine, Division of Infectious Diseases, Medical School, University of Patras, 26500 Patras, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Georgios","family":"Decavalas","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Medical School, University of Patras, Rio Achaia, 26500 Patras, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-3083.2006.01487.x"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1067\/mob.2002.126000a"},{"issue":"1","key":"3","doi-asserted-by":"crossref","first-page":"44","DOI":"10.1097\/00063110-200402000-00009","volume":"11","year":"2004","journal-title":"European Journal of Emergency Medicine"},{"issue":"2","key":"4","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1097\/00001432-200104000-00003","volume":"14","year":"2001","journal-title":"Current Opinion in Infectious Diseases"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199611000-00011"},{"issue":"2","key":"6","doi-asserted-by":"crossref","first-page":"274","DOI":"10.1016\/S0002-9378(87)80150-3","volume":"157","year":"1987","journal-title":"American Journal of Obstetrics and Gynecology"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1210\/jc.74.3.645"},{"issue":"5","key":"8","first-page":"823","volume":"87","year":"1996","journal-title":"Obstetrics and Gynecology"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1001\/jama.246.15.1717"},{"issue":"5","key":"10","doi-asserted-by":"crossref","first-page":"558","DOI":"10.1097\/00000658-199505000-00013","volume":"221","year":"1995","journal-title":"Annals of Surgery"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.130.9.1150"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/S0736-4679(98)00013-4"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/S1072-7515(98)00192-6"},{"issue":"6","key":"15","doi-asserted-by":"crossref","first-page":"784","DOI":"10.1016\/0002-9610(83)90140-X","volume":"145","year":"1983","journal-title":"American Journal of Surgery"},{"issue":"4","key":"16","doi-asserted-by":"crossref","first-page":"488","DOI":"10.1002\/bjs.1800780431","volume":"78","year":"1991","journal-title":"British Journal of Surgery"},{"issue":"5","key":"17","first-page":"397","volume":"64","year":"1998","journal-title":"American Surgeon"},{"issue":"214","key":"18","first-page":"7","year":"2000","journal-title":"Annales Chirurgiae et Gynaecologiae"},{"issue":"4","key":"19","doi-asserted-by":"crossref","first-page":"800","DOI":"10.1086\/515199","volume":"28","year":"1999","journal-title":"Clinical Infectious Diseases"}],"container-title":["Case Reports in Obstetrics and Gynecology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/criog\/2014\/505410.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criog\/2014\/505410.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/criog\/2014\/505410.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T05:17:29Z","timestamp":1498108649000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/criog\/2014\/505410\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":18,"alternative-id":["505410","505410"],"URL":"https:\/\/doi.org\/10.1155\/2014\/505410","relation":{},"ISSN":["2090-6684","2090-6692"],"issn-type":[{"value":"2090-6684","type":"print"},{"value":"2090-6692","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}