{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2024,8,3]],"date-time":"2024-08-03T16:17:07Z","timestamp":1722701827204},"reference-count":15,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Chronic lymphocytic leukemia (CLL) is associated with a state of immunosuppression characterized by hypogammaglobulinemia as well as B and T lymphocyte dysfunction. Though opportunistic infections are common in CLL patients, particularly after treatment, reports of infections by endemic dimorphic fungi are very few. Here we report a case of pulmonary blastomycosis in a CLL patient who initially presented with an indolent pulmonary mass lesion. The pulmonary lesions progressed rapidly over a two-week period. The diagnosis was established by transbronchial lung biopsy. He was treated with Amphotericin B lipid complex followed by oral itraconazole and recovered uneventfully. This case illustrates the importance of a timely diagnosis and treatment. The presentation of blastomycosis in immunocompromised patients, diagnosis, and treatment are discussed.<\/jats:p>","DOI":"10.1155\/2014\/514382","type":"journal-article","created":{"date-parts":[[2014,4,13]],"date-time":"2014-04-13T21:04:34Z","timestamp":1397423074000},"page":"1-5","source":"Crossref","is-referenced-by-count":1,"title":["Rapid Progression of Pulmonary Blastomycosis in an Untreated Patient of Chronic Lymphocytic Leukemia"],"prefix":"10.1155","volume":"2014","author":[{"given":"Pralay K.","family":"Sarkar","sequence":"first","affiliation":[{"name":"Divisions of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Florida, Gainesville, FL 32608, USA"},{"name":"Pulmonary and Critical Care Medicine, Baylor College of Medicine, One Baylor Plaza, Houston, TX 77030, USA"},{"name":"Ben Taub General Hospital, 1504 Taub Loop, BTGH-6PF80002, Houston, TX 77030, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Paras","family":"Malhotra","sequence":"additional","affiliation":[{"name":"Divisions of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Florida, Gainesville, FL 32608, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P. S.","family":"Sriram","sequence":"additional","affiliation":[{"name":"Divisions of Pulmonary, Critical Care and Sleep Medicine, Department of Medicine, University of Florida, Gainesville, FL 32608, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1053\/adpa.2001.21473"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1080\/00313020212465"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1093\/bmb\/ldn034"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1080\/1042819021000029993"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1007\/s00262-005-0015-8"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.beha.2009.12.004"},{"issue":"3","key":"7","first-page":"359","volume":"125","year":"1982","journal-title":"American Review of Respiratory Disease"},{"issue":"3","key":"8","doi-asserted-by":"crossref","first-page":"289","DOI":"10.1097\/00007611-199903000-00006","volume":"92","year":"1999","journal-title":"Southern Medical Journal"},{"issue":"3","key":"9","doi-asserted-by":"crossref","first-page":"829","DOI":"10.1148\/radiology.182.3.1535903","volume":"182","year":"1992","journal-title":"Radiology"},{"issue":"1","key":"10","doi-asserted-by":"crossref","first-page":"29","DOI":"10.1016\/S0025-6196(12)61172-0","volume":"66","year":"1991","journal-title":"Mayo Clinic Proceedings"},{"issue":"6","key":"11","doi-asserted-by":"crossref","first-page":"1177","DOI":"10.2214\/ajr.154.6.2110723","volume":"154","year":"1990","journal-title":"The American Journal of Roentgenology"},{"issue":"7","key":"12","first-page":"259","volume":"107","year":"2009","journal-title":"The Journal of the Kentucky Medical Association"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1378\/chest.121.3.768"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1086\/313750"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1086\/588300"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2014\/514382.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2014\/514382.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2014\/514382.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T11:31:39Z","timestamp":1498131099000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crim\/2014\/514382\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":15,"alternative-id":["514382","514382"],"URL":"https:\/\/doi.org\/10.1155\/2014\/514382","relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"value":"1687-9627","type":"print"},{"value":"1687-9635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}