{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T17:21:20Z","timestamp":1740158480061,"version":"3.37.3"},"reference-count":51,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,5,5]],"date-time":"2014-05-05T00:00:00Z","timestamp":1399248000000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/100004319","name":"Pfizer","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100004319","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pain Research and Treatment"],"published-print":{"date-parts":[[2014,5,5]]},"abstract":"<jats:p><jats:italic>Background.<\/jats:italic> The aim of this report was to evaluate the clinical profile and previous management of patients with uncontrolled neuropathic pain who were referred to pain clinics. <jats:italic>Methods.<\/jats:italic> We included adult patients with uncontrolled pain who had a score of <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mo>\u2265<\/mml:mo><mml:mn>4<\/mml:mn><\/mml:math> in the DN4 questionnaire. In addition to sociodemographic and clinical data, we evaluated pain levels using a visual analog scale as well as anxiety, depression, sleep, disability, and treatment satisfaction employing validated tools. <jats:italic>Results.<\/jats:italic> A total of 755 patients were included in the study. The patients were predominantly referred to pain clinics by traumatologists (34.3%) and primary care physicians (16.7%). The most common diagnoses were radiculopathy (43%) and pain of oncological origin (14.3%). The major cause for uncontrolled pain was suboptimal treatment (88%). Fifty-three percent of the patients were depressed, 43% had clinical anxiety, 50% rated their overall health as bad or very bad, and 45% noted that their disease was severely or extremely interfering with their daily activities. <jats:italic>Conclusions.<\/jats:italic> Our results showed that uncontrolled neuropathic pain is a common phenomenon among the specialties that address these clinical entities and, regardless of its etiology, uncontrolled pain is associated with a dramatic impact on patient well-being.<\/jats:p>","DOI":"10.1155\/2014\/518716","type":"journal-article","created":{"date-parts":[[2014,5,6]],"date-time":"2014-05-06T01:14:45Z","timestamp":1399338885000},"page":"1-15","source":"Crossref","is-referenced-by-count":1,"title":["Clinical Characteristics, Patient-Reported Outcomes, and Previous Therapeutic Management of Patients with Uncontrolled Neuropathic Pain Referred to Pain Clinics"],"prefix":"10.1155","volume":"2014","author":[{"given":"Jos\u00e9","family":"de Andr\u00e9s","sequence":"first","affiliation":[{"name":"Anesthesia, Critical Care, and Multidisciplinary Pain Management Department, Valencia University General Hospital, Valencia University Medical School, Valencia, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9-Luis","family":"de la Calle","sequence":"additional","affiliation":[{"name":"Pain Unit, Hospital Ram\u00f3n y Cajal, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mar\u00eda","family":"P\u00e9rez","sequence":"additional","affiliation":[{"name":"Medical Unit, Pfizer Espa\u00f1a, Avenida de Europa, 20 B Parque Empresarial La Moraleja, 28108 Alcobendas, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vanessa","family":"L\u00f3pez","sequence":"additional","affiliation":[{"name":"Medical Unit, Pfizer Espa\u00f1a, Avenida de Europa, 20 B Parque Empresarial La Moraleja, 28108 Alcobendas, Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000282763.29778.59"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2005.11.008"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2007.08.013"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.2165\/00044011-200929070-00002"},{"issue":"2","key":"5","doi-asserted-by":"crossref","first-page":"447","DOI":"10.1016\/S1047-9651(18)30801-5","volume":"12","year":"2001","journal-title":"Physical Medicine and Rehabilitation Clinics of North America"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(10)70143-5"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.disamonth.2013.12.001"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2006.04.013"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2006.02.002"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2005.01.014"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2011.09.014"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1007\/s11916-012-0256-0"},{"issue":"11","key":"13","doi-asserted-by":"crossref","first-page":"771","DOI":"10.2165\/00044011-200727110-00004","volume":"27","year":"2007","journal-title":"Clinical Drug Investigation"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpain.2003.12.004"},{"key":"15","doi-asserted-by":"crossref","first-page":"85","DOI":"10.3111\/13696998.2012.729548","volume":"16","year":"2013","journal-title":"Journal of Medical Economics"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2010.02999.x"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/S0885-3924(03)00065-4"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2006.10.004"},{"volume-title":"Neuropathic pain: the pharmacological management of neuropathic pain in adults in non-specialist settings","year":"2010","key":"19"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.4065\/mcp.2009.0649"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1111\/j.1533-2500.2006.00054.x"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2004.12.010"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2003.12.024"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1186\/1477-7525-5-66"},{"issue":"6","key":"25","doi-asserted-by":"crossref","first-page":"361","DOI":"10.1111\/j.1600-0447.1983.tb09716.x","volume":"67","year":"1983","journal-title":"Acta Psychiatrica Scandinavica"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1016\/S0163-8343(03)00043-4"},{"first-page":"235","volume-title":"Sleep measures","year":"1992","key":"27"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2006.05.002"},{"year":"2004","key":"29"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2009.05.008"},{"issue":"2","key":"31","first-page":"77","volume":"28","year":"2000","journal-title":"Actas Espanolas de Psiquiatria"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2288-11-142"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1111\/j.1524-4733.2008.00323.x"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-199605000-00029"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1097\/01.ajp.0000210945.27052.b3"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpainsymman.2005.04.009"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1007\/s11892-011-0202-2"},{"key":"39","doi-asserted-by":"crossref","first-page":"35","DOI":"10.1155\/2014\/480859","volume":"19","year":"2014","journal-title":"Pain Res Manag"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejpain.2009.03.010"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1097\/00002508-200203000-00002"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1016\/S1087-0792(03)00044-3"},{"issue":"1","key":"43","doi-asserted-by":"crossref","first-page":"105","DOI":"10.1016\/0304-3959(88)90282-5","volume":"35","year":"1988","journal-title":"Pain"},{"issue":"6","key":"44","first-page":"559","volume":"14","year":"2011","journal-title":"Pain Physician"},{"key":"45","first-page":"S263","volume":"12","year":"2006","journal-title":"The American Journal of Managed Care"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0b013e3182166ebe"},{"issue":"1","key":"47","doi-asserted-by":"crossref","first-page":"13","DOI":"10.1155\/2007\/730785","volume":"12","year":"2007","journal-title":"Pain Research and Management"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.1016\/j.pain.2008.03.002"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-12-8"},{"key":"50","doi-asserted-by":"publisher","DOI":"10.1111\/j.1533-2500.2006.00079.x"},{"key":"51","doi-asserted-by":"publisher","DOI":"10.1016\/j.jdiacomp.2005.09.007"},{"key":"52","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2377-12-29"}],"container-title":["Pain Research and Treatment"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/2014\/518716.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2014\/518716.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2014\/518716.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T17:13:56Z","timestamp":1607534036000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/prt\/2014\/518716\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,5,5]]},"references-count":51,"alternative-id":["518716","518716"],"URL":"https:\/\/doi.org\/10.1155\/2014\/518716","relation":{},"ISSN":["2090-1542","2090-1550"],"issn-type":[{"type":"print","value":"2090-1542"},{"type":"electronic","value":"2090-1550"}],"subject":[],"published":{"date-parts":[[2014,5,5]]}}}