{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T18:06:02Z","timestamp":1777485962305,"version":"3.51.4"},"reference-count":34,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2014,8,31]],"date-time":"2014-08-31T00:00:00Z","timestamp":1409443200000},"content-version":"vor","delay-in-days":242,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2014,1]]},"abstract":"<jats:p><jats:italic>Objective.<\/jats:italic> To evaluate the efficacy of Xuefu Zhuyu Tang (XFZYT) for treating angina pectoris (AP). <jats:italic>Methods.<\/jats:italic> Six databases were searched (up to December, 2013). Eligible randomized controlled trials (RCTs) evaluating the efficiency of XFZYT plus traditional antianginal medications (TAMs) compared with TAMs alone in patients with AP were included. The outcomes were relief of anginal symptoms (RAS) and improvement of electrocardiogram (ECG) and blood high\u2010density lipoprotein cholesterol (HDL\u2010C) level. <jats:italic>Result.<\/jats:italic> Finally 14 RCTs were included. There were evidences that XFZYT combined with TAMs was more effective in improving RAS (RR = 1.29; 95% CI = [1.20, 1.38]), ECG (RR = 1.37; 95% CI = [1.22, 1.54]), and blood HDL\u2010C level (MD = 0.29\u2009mmol\/L; 95% CI = [0.23, 0.35]) compared with TAMs alone. Our meta\u2010analysis also showed the pooled number needed to treat (NNT) of the group with stable angina pectoris (SAP) was smaller in improving RAS (4.2 versus 5.7) and ECG (3.1 versus 5.5) compared with the group with both SAP and unstable angina pectoris (UAP). <jats:italic>Conclusion.<\/jats:italic> Combination therapy with XFZYT and TAMs is more effective in treating AP compared with TAMs alone. And XFZYT may be a more suitable choice for the treatment of SAP. However, the findings should be interpreted with caution due to the mediocre methodological quality of the included RCTs.<\/jats:p>","DOI":"10.1155\/2014\/521602","type":"journal-article","created":{"date-parts":[[2014,8,31]],"date-time":"2014-08-31T21:02:52Z","timestamp":1409518972000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":24,"title":["The Usefulness of Xuefu Zhuyu Tang for Patients with Angina Pectoris: A Meta\u2010Analysis and Systematic Review"],"prefix":"10.1155","volume":"2014","author":[{"given":"Guo-zhong","family":"Yi","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yu-qin","family":"Qiu","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ya","family":"Xiao","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Li-xia","family":"Yuan","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2014,8,31]]},"reference":[{"key":"e_1_2_9_1_2","volume-title":"Global Status Report on Noncommunicable Diseases 2010","year":"2011"},{"key":"e_1_2_9_2_2","volume-title":"Global Atlas on Cardiovascular Disease Prevention and Control","author":"World Health Organization","year":"2011"},{"key":"e_1_2_9_3_2","doi-asserted-by":"publisher","DOI":"10.1136\/hrt.2010.204511"},{"key":"e_1_2_9_4_2","doi-asserted-by":"publisher","DOI":"10.1136\/heartjnl-2011-301436"},{"key":"e_1_2_9_5_2","doi-asserted-by":"publisher","DOI":"10.1586\/14779072.2014.880339"},{"key":"e_1_2_9_6_2","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2003.08.065"},{"key":"e_1_2_9_7_2","first-page":"1732","article-title":"Research progress of Xuefu Zhuyu decoction in the treatment of Cardiovascular and Cerebrovascular Disease","volume":"28","author":"Wang H. 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