{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,14]],"date-time":"2026-04-14T13:55:05Z","timestamp":1776174905629,"version":"3.50.1"},"reference-count":19,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"Addis Zemen health center"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Background.<\/jats:italic>Visceral leishmaniasis (VL) is a systemic disease caused by the<jats:italic>Leishmania donovani<\/jats:italic>complex. It is one of the fatal diseases if left untreated. In Ethiopia, there are many VL endemic foci. The aim of this study was to determine the trends of VL in the study area.<jats:italic>Methodology.<\/jats:italic>A retrospective study was conducted at Addis Zemen health center from September 2005 to August 2011. Data were collected from laboratory registration book and entered and analyzed by using SPSS version 20 software and<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>P<\/mml:mi><\/mml:mrow><\/mml:math>value of \u22640.05 was considered statistically significant.<jats:italic>Result.<\/jats:italic>A total of 7161 VL suspected cases were reported in the study area. The overall prevalence of VL was 2801 (39.1%). Of the 2801 VL positive cases, the highest annual prevalence, 988 (46.8%), was reported in 2005 but the trend gradually decreases. Majority of the VL confirmed cases were in the age groups of 5\u201314 years and males were more affected.<jats:italic>Conclusion.<\/jats:italic>The prevalence of VL in the study area was high in early 2005 but, gradually, the trend has been decreased and it becomes one of VL endemic foci in Ethiopia.<\/jats:p>","DOI":"10.1155\/2014\/545393","type":"journal-article","created":{"date-parts":[[2014,3,27]],"date-time":"2014-03-27T07:24:55Z","timestamp":1395905095000},"page":"1-5","source":"Crossref","is-referenced-by-count":18,"title":["Trend Analysis of Visceral Leishmaniasis at Addis Zemen Health Center, Northwest Ethiopia"],"prefix":"10.1155","volume":"2014","author":[{"given":"Yitayih","family":"Wondimeneh","sequence":"first","affiliation":[{"name":"School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O. Box 196, Gondar, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yegnasew","family":"Takele","sequence":"additional","affiliation":[{"name":"Gondar University Leishmaniasis Research and Treatment Centre, University of Gondar, P.O. Box 196, Gondar, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Asmamaw","family":"Atnafu","sequence":"additional","affiliation":[{"name":"School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O. Box 196, Gondar, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Getachew","family":"Ferede","sequence":"additional","affiliation":[{"name":"School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O. Box 196, Gondar, Ethiopia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dagnachew","family":"Muluye","sequence":"additional","affiliation":[{"name":"School of Biomedical and Laboratory Sciences, College of Medicine and Health Sciences, University of Gondar, P.O. 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