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It combines the existing scattering coefficient model and spectral domain OCT to achieve method of early diagnosis of colorectal polyp in hospitals. Seventeen patients were studied, and a total of 1456 data points were extracted by curve-fitting the OCT signals into a confocal single-backscattering model. The results show that the mean scattering coefficient value for colorectal polyps is 1.91\u2009mm<jats:sup>\u22121<\/jats:sup>(std: \u00b10.54\u2009mm<jats:sup>\u22121<\/jats:sup>), which is between the values for normal and malignant tissues. In addition, we studied the difference between adenomatous polyps (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>15<\/mml:mn><\/mml:mrow><\/mml:math>) and inflammatory polyps (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>2<\/mml:mn><\/mml:mrow><\/mml:math>) quantitatively and found that the adenomatous tissues had lower scattering coefficients than the inflammatory ones. The quantitative measurements confirmed that OCT can be used in primary diagnosis to compensate for the deficiencies in methods of pathological diagnosis, with a great potential for early diagnosis of tissues.<\/jats:p>","DOI":"10.1155\/2014\/570629","type":"journal-article","created":{"date-parts":[[2014,4,9]],"date-time":"2014-04-09T21:24:01Z","timestamp":1397078641000},"page":"1-7","source":"Crossref","is-referenced-by-count":6,"title":["Quantitative Diagnosis of Colorectal Polyps by Spectral Domain Optical Coherence Tomography"],"prefix":"10.1155","volume":"2014","author":[{"given":"Chen","family":"Wang","sequence":"first","affiliation":[{"name":"Institute of Modern Optics, Key Laboratory of Optical Information Science & Technology, Ministry of Education of China, Nankai University, Tianjin 300071, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qinqin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Institute of Modern Optics, Key Laboratory of Optical Information Science & Technology, Ministry of Education of China, Nankai University, Tianjin 300071, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Xiaojing","family":"Wu","sequence":"additional","affiliation":[{"name":"Tianjin Union Medicine Centre, Tianjin 300121, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tao","family":"Tang","sequence":"additional","affiliation":[{"name":"Tianjin Union Medicine Centre, Tianjin 300121, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hong","family":"Liu","sequence":"additional","affiliation":[{"name":"Tianjin Union Medicine Centre, Tianjin 300121, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. 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