{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T02:37:59Z","timestamp":1783391879628,"version":"3.54.6"},"reference-count":35,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Purpose.<\/jats:italic>To evaluate the effect of corneal crosslinking in progressive keratoconus by applying in vivo corneal visualization Scheimpflug technology.<jats:italic>Design.<\/jats:italic>Longitudinal retrospective study.<jats:italic>Subjects and Controls.<\/jats:italic>Seventeen eyes of patients treated with corneal crosslinking for progressive keratoconus.<jats:italic>Methods.<\/jats:italic>Corneal visualization Scheimpflug technology analyses (research software version 6.07r08) of subjects with progressive keratoconus before and 3 months after corneal crosslinking (CXL) were reviewed retrospectively.<jats:italic>t-<\/jats:italic>test (for normal distribution) and Wilcoxon matched-pairs test (if not normally distributed) were used to test for statistically significant differences between pre- and post-CXL analyses.<jats:italic>Results.<\/jats:italic>We demonstrated statistically significant differences for the intraocular pressure (median: +3\u2009mmHg,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>P<\/mml:mi><mml:mi mathvariant=\"normal\">\u00a0<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.004<\/mml:mn><\/mml:math>), the central corneal pachymetry (pachy; mean: \u221235\u2009<jats:italic>\u00b5<\/jats:italic>m,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:math>), the timespan between the air impulse release and the first applanation of the cornea (A1time; median: +0.12\u2009ms,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>), and the timespan between the air impulse release and the second applanation of the cornea (A2time; median: \u221237\u2009ms,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>).<jats:italic>Conclusions.<\/jats:italic>With the A1time and the A2time, we identified two parameters that demonstrated a statistically significant improvement of the biomechanical properties of the cornea after CXL. Despite the known initial decrease of the pachymetry after CXL, none of the analyzed parameters indicated a progression of the keratoconus.<\/jats:p>","DOI":"10.1155\/2014\/579190","type":"journal-article","created":{"date-parts":[[2014,9,22]],"date-time":"2014-09-22T17:01:36Z","timestamp":1411405296000},"page":"1-8","source":"Crossref","is-referenced-by-count":16,"title":["Corneal Biomechanical Changes after Crosslinking for Progressive Keratoconus with the Corneal Visualization Scheimpflug Technology"],"prefix":"10.1155","volume":"2014","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-3091-9347","authenticated-orcid":true,"given":"Johannes","family":"Steinberg","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, UKE-University Medical Center Hamburg-Eppendorf, Martinistra\u00dfe 52, 20246 Hamburg, Germany"},{"name":"Care-Vision Germany, University Medical Center Hamburg-Eppendorf, Martinistra\u00dfe 52, 20246 Hamburg, 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