{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T16:32:02Z","timestamp":1740155522758,"version":"3.37.3"},"reference-count":16,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/100000774","name":"Defense Threat Reduction Agency","doi-asserted-by":"publisher","id":[{"id":"10.13039\/100000774","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Tropical Medicine"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Brucellosis infection is a multisystem disease, with a broad spectrum of symptoms. We investigated the existence of clusters of infected patients according to their clinical presentation. Using national surveillance data from the Electronic-Integrated Disease Surveillance System, we applied a latent class cluster (LCC) analysis on symptoms to determine clusters of brucellosis cases. A total of 454 cases reported between July 2011 and July 2013 were analyzed. LCC identified a two-cluster model and the Vuong-Lo-Mendell-Rubin likelihood ratio supported the cluster model. Brucellosis cases in the second cluster (19%) reported higher percentages of poly-lymphadenopathy, hepatomegaly, arthritis, myositis, and neuritis and changes in liver function tests compared to cases of the first cluster. Patients in the second cluster had a severe brucellosis disease course and were associated with longer delay in seeking medical attention. Moreover, most of them were from Beylagan, a region focused on sheep and goat livestock production in south-central Azerbaijan. Patients in cluster 2 accounted for one-quarter of brucellosis cases and had a more severe clinical presentation. Delay in seeking medical care may explain severe illness. Future work needs to determine the factors that influence brucellosis case seeking and identify brucellosis species, particularly among cases from Beylagan.<\/jats:p>","DOI":"10.1155\/2014\/593873","type":"journal-article","created":{"date-parts":[[2014,12,14]],"date-time":"2014-12-14T16:01:19Z","timestamp":1418572879000},"page":"1-4","source":"Crossref","is-referenced-by-count":4,"title":["Patterns of Brucellosis Infection Symptoms in Azerbaijan: A Latent Class Cluster Analysis"],"prefix":"10.1155","volume":"2014","author":[{"given":"Rita","family":"Ismayilova","sequence":"first","affiliation":[{"name":"Republican Anti-Plague Station, Baku, Azerbaijan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Emilya","family":"Nasirova","sequence":"additional","affiliation":[{"name":"Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Colleen","family":"Hanou","sequence":"additional","affiliation":[{"name":"Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert G.","family":"Rivard","sequence":"additional","affiliation":[{"name":"U.S. Army Medical Research Institute of Infectious Diseases, Fort Detrick, Frederick, MD 21702, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian T.","family":"Bautista","sequence":"additional","affiliation":[{"name":"Walter Reed Army Institute of Research, Silver Spring, MD 20910, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"doi-asserted-by":"publisher","key":"1","DOI":"10.1186\/1471-2334-12-185"},{"doi-asserted-by":"publisher","key":"2","DOI":"10.1371\/journal.pntd.0001929"},{"doi-asserted-by":"publisher","key":"4","DOI":"10.1016\/s1473-3099(06)70382-6"},{"doi-asserted-by":"publisher","key":"5","DOI":"10.4269\/ajtmh.12-0381"},{"key":"6","first-page":"8","volume":"2","year":"2011","journal-title":"Molekuliarnaia Genetika, Mikrobiologiia i Virusologiia"},{"key":"7","first-page":"171","volume":"2","year":"2007","journal-title":"Advances in Disease Surveillance"},{"volume-title":"Latent class cluster analysis","year":"2002","first-page":"89","key":"8"},{"volume-title":"Chapter 36: cluster analysis and latent class clustering techniques","year":"2013","first-page":"645","key":"9"},{"doi-asserted-by":"publisher","key":"10","DOI":"10.1080\/10705510701575396"},{"doi-asserted-by":"publisher","key":"11","DOI":"10.1056\/nejmra050570"},{"issue":"10","key":"12","first-page":"168","volume":"22","year":"1947","journal-title":"Memphis Medical Journal"},{"doi-asserted-by":"publisher","key":"13","DOI":"10.1016\/j.diagmicrobio.2006.09.008"},{"doi-asserted-by":"publisher","key":"14","DOI":"10.3109\/13550280903586386"},{"doi-asserted-by":"publisher","key":"15","DOI":"10.1016\/s0973-3698(11)60036-8"},{"doi-asserted-by":"publisher","key":"16","DOI":"10.1016\/j.ijid.2009.06.031"},{"key":"17","series-title":"NATO Science for Peace and Security Series A: Chemistry and Biology","first-page":"39","volume-title":"Especially dangerous infections in Azerbaijan","year":"2010"}],"container-title":["Journal of Tropical Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jtm\/2014\/593873.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jtm\/2014\/593873.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jtm\/2014\/593873.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,7,28]],"date-time":"2016-07-28T22:35:51Z","timestamp":1469745351000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/jtm\/2014\/593873\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":16,"alternative-id":["593873","593873"],"URL":"https:\/\/doi.org\/10.1155\/2014\/593873","relation":{},"ISSN":["1687-9686","1687-9694"],"issn-type":[{"type":"print","value":"1687-9686"},{"type":"electronic","value":"1687-9694"}],"subject":[],"published":{"date-parts":[[2014]]}}}