{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T00:35:11Z","timestamp":1783989311921,"version":"3.55.0"},"reference-count":28,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Scientific World Journal"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. The local anaesthetics used in day-case spinal anaesthesia should provide short recovery times. We aimed to compare hyperbaric prilocaine and bupivacaine in terms of sensory block resolution and time to home readiness in day-case spinal anaesthesia.<jats:italic>Methods<\/jats:italic>. Fifty patients undergoing perianal surgery were randomized into two groups. The bupivacaine-fentanyl group (Group B) received 7.5\u2009mg, 0.5% hyperbaric bupivacaine + 20\u2009<jats:italic>\u03bc<\/jats:italic>g fentanyl in total 1.9\u2009mL. The prilocaine-fentanyl group (Group P) received 30\u2009mg, 0.5% hyperbaric prilocaine + 20\u2009<jats:italic>\u03bc<\/jats:italic>g fentanyl in the same volume.<jats:italic>Results<\/jats:italic>. Time to L1 block and maximum block was shorter in Group P than in Group B (Group P<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mn>4.6<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>1.3<\/mml:mn><\/mml:math>\u2009min versus Group B<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mn>5.9<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>01.9<\/mml:mn><\/mml:math>\u2009min,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.017<\/mml:mn><\/mml:math>, and Group P<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mn>13.2<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>7.5<\/mml:mn><\/mml:math>\u2009min versus Group B<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mn>15.3<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>6.6<\/mml:mn><\/mml:math>\u2009min,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.04<\/mml:mn><\/mml:math>). The time to L1 regression and S3 regression of the sensorial block was significantly shorter in Group P than in Group B (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mn>45.7<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>21.9<\/mml:mn><\/mml:math>\u2009min versus<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\"><mml:mn>59.7<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>20.9<\/mml:mn><\/mml:math>\u2009min,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M9\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.024<\/mml:mn><\/mml:math>, and<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M10\"><mml:mn>133.8<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>41.4<\/mml:mn><\/mml:math>\u2009min versus<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M11\"><mml:mn>200.4<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>64.8<\/mml:mn><\/mml:math>\u2009min,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M12\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:math>). The mean time to home readiness was shorter for Group P than for Group B (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M13\"><mml:mn>155<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>100.2<\/mml:mn><\/mml:math>\u2009min versus<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M14\"><mml:mn>207.2<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>62.7<\/mml:mn><\/mml:math>\u2009min<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M15\"><mml:mo stretchy=\"false\">(<\/mml:mo><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><mml:mo stretchy=\"false\">)<\/mml:mo><\/mml:math>).<jats:italic>Conclusion<\/jats:italic>. Day-case spinal anaesthesia with hyperbaric prilocaine + fentanyl is superior to hyperbaric bupivacaine in terms of earlier sensory block resolution and home readiness and the surgical conditions are comparable for perianal surgery.<\/jats:p>","DOI":"10.1155\/2014\/608372","type":"journal-article","created":{"date-parts":[[2014,10,14]],"date-time":"2014-10-14T21:56:58Z","timestamp":1413323818000},"page":"1-6","source":"Crossref","is-referenced-by-count":19,"title":["Spinal Anaesthesia with Hyperbaric Prilocaine in Day-Case Perianal Surgery: Randomised Controlled Trial"],"prefix":"10.1155","volume":"2014","author":[{"given":"Ozden Gorgoz","family":"Kaban","sequence":"first","affiliation":[{"name":"Ministry of Health, Diskapi Yildirim Beyazit Training and Research Hospital, Irfan Bastug Caddesi 112 Alt\u0131nda\u011f, Akasya Sokak 9\/10 Koru Mah. 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