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This study investigates the seldom but severe complication of fatigue failure of polyethylene components at mobile bearing total knee arthroplasty designs. Assuming a combination of a floor-based lifestyle and tibial malrotation as a possible reason for a higher failure rate in Asian countries we developed a simplified finite element model considering a tibiofemoral roll-back angle of 22\u00b0 and the range of rotational motion of a clinically established floating platform design (e.motion FP) at a knee flexion angle of 120\u00b0 in order to compare our results to failure modes found in retrieved implants. Compared to the failure mode observed in the clinical retrievals the locations of the occurring stress maxima as well as the tensile stress distribution show analogies. From our observations, we conclude that the newly introduced finite element model with an overlay of deep knee flexion (lateral roll-back) and considerable internally rotated tibia implant positioning is an appropriate analysis for knee design optimizations and a suitable method to predict clinical failure modes.<\/jats:p>","DOI":"10.1155\/2014\/612838","type":"journal-article","created":{"date-parts":[[2014,11,20]],"date-time":"2014-11-20T16:19:20Z","timestamp":1416500360000},"page":"1-10","source":"Crossref","is-referenced-by-count":12,"title":["Differences in Anatomy and Kinematics in Asian and Caucasian TKA Patients: Influence on Implant Positioning and Subsequent Loading Conditions in Mobile Bearing Knees"],"prefix":"10.1155","volume":"2014","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-2995-4556","authenticated-orcid":true,"given":"Allan","family":"Maas","sequence":"first","affiliation":[{"name":"Aesculap AG Research & Development, Am Aesculap-Platz, 78532 Tuttlingen, 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