{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,15]],"date-time":"2026-01-15T00:29:12Z","timestamp":1768436952175,"version":"3.49.0"},"reference-count":15,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Second lymphoid neoplasms are an uncommon but recognized feature of non-Hodgkin\u2019s lymphomas, putatively arising secondary to common genetic or environmental risk factors. Previous limited evaluations of clonal relatedness between successive mature B-cell malignancies have yielded mixed results. We describe the case of a man with intravascular large B-cell lymphoma involving the central nervous system who went into clinical remission following immunochemotherapy and brain radiation, only to relapse 2 years later with a plasmacytoma of bone causing cauda equina syndrome. The plasmacytoma stained strongly for the cell cycle regulator cyclin D1 on immunohistochemistry, while the original intravascular large cell lymphoma was negative, a disparity providing no support for clonal identity between the 2 neoplasms. Continued efforts atcataloging and evaluating unique associations of B-cell malignancies are critical to improving understanding of overarching disease biology in B-cell malignancies.<\/jats:p>","DOI":"10.1155\/2014\/620423","type":"journal-article","created":{"date-parts":[[2014,2,18]],"date-time":"2014-02-18T16:03:09Z","timestamp":1392739389000},"page":"1-6","source":"Crossref","is-referenced-by-count":5,"title":["One Patient, Two Uncommon B-Cell Neoplasms: Solitary Plasmacytoma following Complete Remission from Intravascular Large B-Cell Lymphoma Involving Central Nervous System"],"prefix":"10.1155","volume":"2014","author":[{"given":"Joycelyn","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Medical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Outram Road, Singapore 169610"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soo Yong","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Pathology, Singapore General Hospital, 11 Jalan Tan Tock Seng, Singapore 169608"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leonard H. C.","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Pathology, Singapore General Hospital, 11 Jalan Tan Tock Seng, Singapore 169608"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hwei Yee","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tan Tock Seng Hospital, Singapore 308433"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Khoon Leong","family":"Chuah","sequence":"additional","affiliation":[{"name":"Department of Pathology, Tan Tock Seng Hospital, Singapore 308433"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tiffany","family":"Tang","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Outram Road, Singapore 169610"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Richard","family":"Quek","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Outram Road, Singapore 169610"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kevin","family":"Tay","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Outram Road, Singapore 169610"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Miriam","family":"Tao","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Outram Road, Singapore 169610"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Soon Thye","family":"Lim","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Outram Road, Singapore 169610"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamad","family":"Farid","sequence":"additional","affiliation":[{"name":"Department of Medical Oncology, National Cancer Centre Singapore, 11 Hospital Drive, Outram Road, Singapore 169610"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6602654"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1097\/PAS.0b013e31802d68e9"},{"issue":"1","key":"3","doi-asserted-by":"crossref","first-page":"55","DOI":"10.1111\/j.1365-2141.1985.tb02963.x","volume":"59","year":"1985","journal-title":"British Journal of Haematology"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2141.2007.06866.x"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-05-1545"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2008.291"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.5858\/arpa.2010-0747-RS"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1186\/2162-3619-1-37"},{"issue":"5","key":"9","doi-asserted-by":"crossref","first-page":"1505","DOI":"10.1016\/S0002-9440(10)65022-5","volume":"156","year":"2000","journal-title":"American Journal of Pathology"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-11-013458"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2005-01-0034"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.33.3419"},{"issue":"1","key":"13","doi-asserted-by":"crossref","first-page":"107","DOI":"10.1097\/01.LAB.0000050762.61660.27","volume":"83","year":"2003","journal-title":"Laboratory Investigation"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2009.294"},{"issue":"5","key":"15","doi-asserted-by":"crossref","first-page":"768","DOI":"10.1111\/j.1939-1676.2004.tb02621.x","volume":"18","year":"2004","journal-title":"Journal of Veterinary Internal Medicine"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2014\/620423.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2014\/620423.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2014\/620423.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T04:06:41Z","timestamp":1498104401000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crim\/2014\/620423\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":15,"alternative-id":["620423","620423"],"URL":"https:\/\/doi.org\/10.1155\/2014\/620423","relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"value":"1687-9627","type":"print"},{"value":"1687-9635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}