{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,1]],"date-time":"2025-11-01T02:36:23Z","timestamp":1761964583787,"version":"3.37.3"},"reference-count":15,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Hematology"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Pulmonary involvement with multiple myeloma is rare. We report the case of a 61-year-old man with past medical history of chronic respiratory failure with emphysema, and a known multiple myeloma (Durie and Salmon stage III B and t(4;14) translocation). Six months after diagnosis and first line of treatment, he presented acute dyspnea with interstitial lung disease. Computed tomography showed severe bullous emphysema and diffuse, patchy, multifocal infiltrations bilaterally with nodular character, small bilateral pleural effusions, mediastinal lymphadenopathy, and a known lytic lesion of the 12th vertebra. He was treated with piperacillin-tazobactam, amikacin, oseltamivir, and methylprednisolone. Finally, outcome was unfavourable. Postmortem analysis revealed diffuse and nodular infracentimetric infiltration of the lung parenchyma by neoplastic plasma cells. Physicians should be aware that acute respiratory distress syndrome not responding to treatment of common causes could be a manifestation of the disease, even with negative BAL or biopsy and could be promptly treated with salvage therapy.<\/jats:p>","DOI":"10.1155\/2014\/635237","type":"journal-article","created":{"date-parts":[[2014,8,6]],"date-time":"2014-08-06T17:03:24Z","timestamp":1407344604000},"page":"1-3","source":"Crossref","is-referenced-by-count":1,"title":["Lung Postmortem Autopsy Revealing Extramedullary Involvement in Multiple Myeloma Causing Acute Respiratory Distress Syndrome"],"prefix":"10.1155","volume":"2014","author":[{"given":"Aur\u00e9lie","family":"Ravinet","sequence":"first","affiliation":[{"name":"R\u00e9animation Adultes et Unit\u00e9 de Soins Continus, CHU Estaing, 1 Place Lucie-et-Raymond-Aubrac, CHU Clermont-Ferrand, 63003 Clermont-Ferrand, France"},{"name":"Service d\u2019H\u00e9matologie, CHU Estaing, CHU Clermont-Ferrand, 1 Place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00e9bastien","family":"Perbet","sequence":"additional","affiliation":[{"name":"R\u00e9animation Adultes et Unit\u00e9 de Soins Continus, CHU Estaing, 1 Place Lucie-et-Raymond-Aubrac, CHU Clermont-Ferrand, 63003 Clermont-Ferrand, France"},{"name":"R2D2, EA 7281, INSERM, Facult\u00e9 de M\u00e9decine, Universit\u00e9 d\u2019Auvergne, Place Henri Dunant, 63001 Clermont-Ferrand, France"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Romain","family":"Gui\u00e8ze","sequence":"additional","affiliation":[{"name":"Service d\u2019H\u00e9matologie, CHU Estaing, CHU Clermont-Ferrand, 1 Place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand, France"},{"name":"INSERM CIC-501, EA 7283, CHU Estaing, Universit\u00e9 d\u2019Auvergne, 1 Place Lucie-et-Raymond-Aubrac, 63003 Clermont-Ferrand, 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