{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T16:46:27Z","timestamp":1790786787922,"version":"4.1.0"},"reference-count":18,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2014]]},"abstract":"Aim<\/jats:italic>. To estimate the clinical significance of anti-acetylcholine receptor antibody (anti-AChR-Ab) levels in suspected ocular myasthenia gravis.Methods<\/jats:italic>. In total, 144 patients complaining of fluctuating diplopia and ptosis were evaluated for serum levels of anti-acetylcholine receptor antibody and their medical charts were retrospectively reviewed. Subjects were classified into three groups: variable diplopia only, ptosis only, and both variable diplopia and ptosis. We investigated serum anti-AChR-Ab titer levels and performed thyroid autoantibody tests.Results<\/jats:italic>. Patients\u2019 chief complaints were diplopia (N<\/mml:mi>=<\/mml:mo>103<\/mml:mn><\/mml:math>), ptosis (N<\/mml:mi>=<\/mml:mo>12<\/mml:mn><\/mml:math>), and their concurrence (N<\/mml:mi>=<\/mml:mo>29<\/mml:mn><\/mml:math>). Abnormal anti-AChR-Ab was observed in 21 of 144 patients (14.1%). Between the three groups, mean age, number of seropositive patients, and mean anti-AChR-Ab level were not significantly different (P<\/mml:mi>=<\/mml:mo>0.224<\/mml:mn><\/mml:math>, 0.073, and 0.062, resp.). Overall, 27.5% of patients had abnormal thyroid autoantibodies.Conclusion<\/jats:italic>. The sensitivity of anti-AChR-Ab was 14.1% in suspected ocular myasthenia gravis and seropositivity in myasthenia gravis patients showed a high correlation with the presence of thyroid autoantibodies.<\/jats:p>","DOI":"10.1155\/2014\/689792","type":"journal-article","created":{"date-parts":[[2014,11,13]],"date-time":"2014-11-13T21:02:42Z","timestamp":1415912562000},"page":"1-4","source":"Crossref","is-referenced-by-count":4,"title":["The Anti-Acetylcholine Receptor Antibody Test in Suspected Ocular Myasthenia Gravis"],"prefix":"10.1155","volume":"2014","author":[{"given":"Jung Jin","family":"Lee","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Kim\u2019s Eye Hospital, Konyang University College of Medicine, Youngdeungpo 4th 156, Youngdeungpo-gu, Seoul 150-034, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyung Min","family":"Koh","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Kim\u2019s Eye Hospital, Konyang University College of Medicine, Youngdeungpo 4th 156, Youngdeungpo-gu, Seoul 150-034, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ungsoo Samuel","family":"Kim","sequence":"additional","affiliation":[{"name":"Department of Ophthalmology, Kim\u2019s Eye Hospital, Konyang University College of Medicine, Youngdeungpo 4th 156, Youngdeungpo-gu, Seoul 150-034, Republic of Korea"},{"name":"Department of Ophthalmology, Konyang University College of Medicine, Daejeon 302-718, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(93)90132-I"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2007.02038.x"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000263481.14289.90"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.60.2.243"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2006.05.006"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1002\/ana.410160502"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.3109\/00207454.2010.539307"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.48.12.1246"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(83)90095-3"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1097\/CND.0b013e31821c5634"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1080\/15569520701830992"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1007\/BF01675867"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1007\/BF03346432"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1001\/jama.250.18.2516"},{"issue":"1","key":"15","first-page":"100","volume":"51","year":"2003","journal-title":"Neurology India"},{"key":"16","first-page":"111","volume":"38-39","year":"2000","journal-title":"Romanian Journal of Internal Medicine"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1055\/s-0032-1304598"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.1996.00550080128020"}],"container-title":["Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2014\/689792.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2014\/689792.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2014\/689792.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T23:46:06Z","timestamp":1471563966000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/joph\/2014\/689792\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":18,"alternative-id":["689792","689792"],"URL":"https:\/\/doi.org\/10.1155\/2014\/689792","relation":{},"ISSN":["2090-004X","2090-0058"],"issn-type":[{"value":"2090-004X","type":"print"},{"value":"2090-0058","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}