{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T02:27:29Z","timestamp":1791599249859,"version":"4.3.4"},"reference-count":23,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,9,16]],"date-time":"2014-09-16T00:00:00Z","timestamp":1410825600000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Advances in Bioinformatics"],"published-print":{"date-parts":[[2014,9,16]]},"abstract":"<jats:p>The preliminary study presented within this paper shows a comparative study of various texture features extracted from liver ultrasonic images by employing Multilayer Perceptron (MLP), a type of artificial neural network, to study the presence of disease conditions. An ultrasound (US) image shows echo-texture patterns, which defines the organ characteristics. Ultrasound images of liver disease conditions such as \u201cfatty liver,\u201d \u201ccirrhosis,\u201d and \u201chepatomegaly\u201d produce distinctive echo patterns. However, various ultrasound imaging artifacts and speckle noise make these echo-texture patterns difficult to identify and often hard to distinguish visually. Here, based on the extracted features from the ultrasonic images, we employed an artificial neural network for the diagnosis of disease conditions in liver and finding of the best classifier that distinguishes between abnormal and normal conditions of the liver. Comparison of the overall performance of all the feature classifiers concluded that \u201cmixed feature set\u201d is the best feature set. It showed an excellent rate of accuracy for the training data set. The gray level run length matrix (GLRLM) feature shows better results when the network was tested against unknown data.<\/jats:p>","DOI":"10.1155\/2014\/708279","type":"journal-article","created":{"date-parts":[[2014,9,17]],"date-time":"2014-09-17T01:45:15Z","timestamp":1410918315000},"page":"1-14","source":"Crossref","is-referenced-by-count":72,"title":["Artificial Neural Network Application in the Diagnosis of Disease Conditions with Liver Ultrasound Images"],"prefix":"10.1155","volume":"2014","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-4639-6616","authenticated-orcid":true,"given":"Karthik","family":"Kalyan","sequence":"first","affiliation":[{"name":"Systems Biomedicine Division, Haffkine Institute for Training Research and Testing, Parel, Mumbai, Maharashtra 400012, 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