{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,23]],"date-time":"2026-06-23T21:48:58Z","timestamp":1782251338769,"version":"3.54.5"},"reference-count":30,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2012M521586"],"award-info":[{"award-number":["2012M521586"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2012J2200029"],"award-info":[{"award-number":["2012J2200029"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Pearl Rivers Science and Technology Star","award":["2012M521586"],"award-info":[{"award-number":["2012M521586"]}]},{"name":"Pearl Rivers Science and Technology Star","award":["2012J2200029"],"award-info":[{"award-number":["2012J2200029"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["The Scientific World Journal"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Heart myxoma-related embolisms commonly involve the central nervous system, but data are lacking in Chinese patients.<jats:italic>Methods<\/jats:italic>. 27 patients diagnosed with myxoma were reviewed retrospectively.<jats:italic>Results<\/jats:italic>. Among 27 patients, fourteen (51.9%) patients were women. Fifteen (55.6%) patients had brain embolisms. Rarely, patients were misdiagnosed with central nervous system vasculitis (<jats:italic>n<\/jats:italic>= 2), moyamoya disease (<jats:italic>n<\/jats:italic>= 1), and neuromyelitis optica (<jats:italic>n<\/jats:italic>= 1). We found positive associations between mRS (&gt;3) and female gender (<jats:italic>r<\/jats:italic>= 0.873,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.0001<\/mml:mn><\/mml:math>), infection (<jats:italic>r<\/jats:italic>= 0.722,<jats:italic>P<\/jats:italic>= 0.002), severe complications (<jats:italic>r<\/jats:italic>= 0.722,<jats:italic>P<\/jats:italic>= 0.002), systolic blood pressure (SBP) of &lt;120\u2009mmHg (<jats:italic>r<\/jats:italic>= 0.6,<jats:italic>P<\/jats:italic>= 0.018), WBC count of &gt;10<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:mo>\u00d7<\/mml:mo><\/mml:mrow><\/mml:math>10<jats:sup>9<\/jats:sup>\/L (<jats:italic>r<\/jats:italic>= 0.722,<jats:italic>P<\/jats:italic>= 0.002), tumour size (<jats:italic>r<\/jats:italic>= 0.866,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.0001<\/mml:mn><\/mml:math>), bilateral brain lesions (<jats:italic>r<\/jats:italic>= 0.60,<jats:italic>P<\/jats:italic>= 0.018), and total anterior circulation infarction (TACI) (<jats:italic>r<\/jats:italic>= 0.667,<jats:italic>P<\/jats:italic>= 0.007). The independent relationships among these factors and outcomes could not be confirmed (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>P<\/mml:mi><mml:mo>&gt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>).<jats:italic>Conclusions<\/jats:italic>. Neurologic manifestations in Chinese patients with cardiac myxoma-related stroke were complicated and multifarious. Female gender, infection, other severe complications, low SBP, tumour size, bilateral brain lesions, TACI, and high WBC counts could be associated with a poor prognosis.<\/jats:p>","DOI":"10.1155\/2014\/718246","type":"journal-article","created":{"date-parts":[[2014,3,9]],"date-time":"2014-03-09T17:01:41Z","timestamp":1394384501000},"page":"1-8","source":"Crossref","is-referenced-by-count":7,"title":["Brain Embolism Secondary to Cardiac Myxoma in Fifteen Chinese Patients"],"prefix":"10.1155","volume":"2014","author":[{"given":"Youming","family":"Long","sequence":"first","affiliation":[{"name":"Key Laboratory of Neurogenetics and Channelopathies of Guangdong Province and The Ministry of Education of China, Institute of Neuroscience and the Second Affiliated Hospital of GuangZhou Medical University, 250 Changgang East Road, Guangzhou, Guangdong 510260, China"},{"name":"Department of Neurology, The Second Affiliated Hospital of GuangZhou Medical University, 250 Changgang East Road, 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