{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T20:49:46Z","timestamp":1775508586452,"version":"3.50.1"},"reference-count":21,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Pulmonary Medicine"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Objectives<\/jats:italic>. Relationships of mechanical ventilation to pneumothorax in neonates and care procedures in particular are rarely studied. We aimed to evaluate the relationship of selected ventilator variables and risk events to pneumothorax.<jats:italic>Methods<\/jats:italic>. Pneumothorax was defined as accumulation of air in pleural cavity as confirmed by chest radiograph. Relationship of ventilator mode, selected settings, and risk procedures prior to detection of pneumothorax was studied using matched controls.<jats:italic>Results<\/jats:italic>. Of 540 neonates receiving mechanical ventilation, 10 (1.85%) were found to have pneumothorax. Respiratory distress syndrome, meconium aspiration syndrome, and pneumonia were the underlying lung pathology. Pneumothorax mostly (80%) occurred within 48 hours of life. Among ventilated neonates, significantly higher percentage with pneumothorax received mandatory ventilation than controls (70% versus 20%;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.01<\/mml:mn><\/mml:math>). Peak inspiratory pressure &gt;20\u2009cm<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:msub><mml:mtext>H<\/mml:mtext><mml:mtext>2<\/mml:mtext><\/mml:msub><mml:mtext>O<\/mml:mtext><\/mml:mrow><\/mml:math>and overventilation were not significantly associated with pneumothorax. More cases than controls underwent care procedures in the preceding 3 hours of pneumothorax event. Mean airway pressure change (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.052<\/mml:mn><\/mml:math>) and endotracheal suctioning (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>) were not significantly associated with pneumothorax. Reintubation (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.003<\/mml:mn><\/mml:math>), and bagging (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.015<\/mml:mn><\/mml:math>) were significantly associated with pneumothorax.<jats:italic>Conclusion<\/jats:italic>. Pneumothorax among ventilated neonates occurred at low frequency. Mandatory ventilation and selected care procedures in the preceding 3 hours had significant association.<\/jats:p>","DOI":"10.1155\/2014\/727323","type":"journal-article","created":{"date-parts":[[2014,4,28]],"date-time":"2014-04-28T21:05:22Z","timestamp":1398719122000},"page":"1-4","source":"Crossref","is-referenced-by-count":11,"title":["Frequency and Intensive Care Related Risk Factors of Pneumothorax in Ventilated Neonates"],"prefix":"10.1155","volume":"2014","author":[{"given":"Ramesh","family":"Bhat Yellanthoor","sequence":"first","affiliation":[{"name":"Department of Paediatrics, Kasturba Medical College, Manipal University, Manipal, Udupi District, Karnataka 576104, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vidya","family":"Ramdas","sequence":"additional","affiliation":[{"name":"Department of Paediatrics, Kasturba Medical College, Manipal University, Manipal, Udupi District, Karnataka 576104, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clp.2007.11.004"},{"issue":"5-6","key":"2","first-page":"271","volume":"54","year":"2000","journal-title":"Medicinski Arhiv"},{"issue":"4","key":"3","doi-asserted-by":"crossref","first-page":"611","DOI":"10.1016\/S0022-3476(05)80964-3","volume":"123","year":"1993","journal-title":"Journal of Pediatrics"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/PCC.0b013e31816c6e55"},{"key":"5","first-page":"487","volume-title":"Pulmonary airleaks","year":"2005"},{"issue":"3","key":"6","doi-asserted-by":"crossref","first-page":"F201","DOI":"10.1136\/adc.85.3.201","volume":"85","year":"2001","journal-title":"Archives of Disease in Childhood: Fetal and Neonatal Edition"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2006.106245"},{"issue":"8","key":"8","first-page":"S135","volume":"88","year":"2005","journal-title":"Journal of the Medical Association of Thailand"},{"issue":"4","key":"9","year":"2004","journal-title":"Cochrane Database of Systematic Reviews"},{"issue":"4","key":"10","year":"2004","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1136\/adc.2004.068437"},{"issue":"2","key":"12","doi-asserted-by":"crossref","first-page":"144","DOI":"10.1542\/peds.69.2.144","volume":"69","year":"1982","journal-title":"Pediatrics"},{"issue":"4","key":"13","first-page":"325","volume":"40","year":"2003","journal-title":"Indian Pediatrics"},{"issue":"3","key":"14","first-page":"242","volume":"50","year":"2008","journal-title":"Turkish Journal of Pediatrics"},{"issue":"1","key":"15","doi-asserted-by":"crossref","first-page":"F5","DOI":"10.1136\/adc.82.1.5","volume":"82","year":"2000","journal-title":"Archives of Disease in Childhood: Fetal and Neonatal Edition"},{"issue":"5","key":"16","first-page":"479","volume":"69","year":"1993","journal-title":"Archives of Disease in Childhood"},{"issue":"1","key":"17","first-page":"45","volume":"21","year":"2011","journal-title":"Iranian Journal of Pediatrics"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa072788"},{"issue":"8367","key":"19","first-page":"1","volume":"1","year":"1984","journal-title":"The Lancet"},{"issue":"3","key":"20","doi-asserted-by":"crossref","first-page":"408","DOI":"10.1203\/00006450-200009000-00025","volume":"48","year":"2000","journal-title":"Pediatric Research"},{"issue":"5","key":"21","doi-asserted-by":"crossref","first-page":"764","DOI":"10.1016\/S0022-3476(83)80254-6","volume":"102","year":"1983","journal-title":"Journal of Pediatrics"}],"container-title":["Pulmonary Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/pm\/2014\/727323.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/pm\/2014\/727323.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/pm\/2014\/727323.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,2]],"date-time":"2022-04-02T12:53:29Z","timestamp":1648904009000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/pm\/2014\/727323\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":21,"alternative-id":["727323","727323"],"URL":"https:\/\/doi.org\/10.1155\/2014\/727323","relation":{},"ISSN":["2090-1836","2090-1844"],"issn-type":[{"value":"2090-1836","type":"print"},{"value":"2090-1844","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}