{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T14:25:06Z","timestamp":1740147906899,"version":"3.37.3"},"reference-count":49,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["30971642","2009CDA161","31000570"],"award-info":[{"award-number":["30971642","2009CDA161","31000570"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003819","name":"Natural Science Foundation of Hubei Province","doi-asserted-by":"publisher","award":["30971642","2009CDA161","31000570"],"award-info":[{"award-number":["30971642","2009CDA161","31000570"]}],"id":[{"id":"10.13039\/501100003819","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["30971642","2009CDA161","31000570"],"award-info":[{"award-number":["30971642","2009CDA161","31000570"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Computational and Mathematical Methods in Medicine"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Associating microRNAs (miRNAs) with cancers is an important step of understanding the mechanisms of cancer pathogenesis and finding novel biomarkers for cancer therapies. In this study, we constructed a miRNA-cancer association network (miCancerna) based on more than 1,000 miRNA-cancer associations detected from millions of abstracts with the text-mining method, including 226 miRNA families and 20 common cancers. We further prioritized cancer-related miRNAs at the network level with the random-walk algorithm, achieving a relatively higher performance than previous miRNA disease networks. Finally, we examined the top 5 candidate miRNAs for each kind of cancer and found that 71% of them are confirmed experimentally. miCancerna would be an alternative resource for the cancer-related miRNA identification.<\/jats:p>","DOI":"10.1155\/2014\/746979","type":"journal-article","created":{"date-parts":[[2014,4,10]],"date-time":"2014-04-10T17:04:37Z","timestamp":1397149477000},"page":"1-8","source":"Crossref","is-referenced-by-count":6,"title":["Establishing Reliable miRNA-Cancer Association Network Based on Text-Mining Method"],"prefix":"10.1155","volume":"2014","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-6757-7152","authenticated-orcid":true,"given":"Lun","family":"Li","sequence":"first","affiliation":[{"name":"Hubei Bioinformatics and Molecular Imaging Key Laboratory, Huazhong University of Science and Technology, Wuhan 430074, China"},{"name":"Biomedical Engineering Department, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3979-1957","authenticated-orcid":true,"given":"Xingchi","family":"Hu","sequence":"additional","affiliation":[{"name":"Hubei Bioinformatics and Molecular Imaging Key Laboratory, Huazhong University of Science and Technology, Wuhan 430074, China"},{"name":"Biomedical Engineering Department, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhaowan","family":"Yang","sequence":"additional","affiliation":[{"name":"Hubei Bioinformatics and Molecular Imaging Key Laboratory, Huazhong University of Science and Technology, Wuhan 430074, China"},{"name":"Biomedical Engineering Department, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1428-904X","authenticated-orcid":true,"given":"Zhenyu","family":"Jia","sequence":"additional","affiliation":[{"name":"Department of Statistics, The University of Akron, Akron, OH 44325, USA"},{"name":"Department of Family & Community Medicine, Northeast Ohio Medical University, Rootstown, OH 44272, USA"},{"name":"Guizhou Provincial Key Laboratory of Computational Nano-Material Science, Guizhou Normal College, Guiyang 550018, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ming","family":"Fang","sequence":"additional","affiliation":[{"name":"Hubei Bioinformatics and Molecular Imaging Key Laboratory, Huazhong University of Science and Technology, Wuhan 430074, China"},{"name":"Biomedical Engineering Department, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Libin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Hubei Bioinformatics and Molecular Imaging Key Laboratory, Huazhong University of Science and Technology, Wuhan 430074, China"},{"name":"Biomedical Engineering Department, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanhong","family":"Zhou","sequence":"additional","affiliation":[{"name":"Hubei Bioinformatics and Molecular Imaging Key Laboratory, Huazhong University of Science and Technology, Wuhan 430074, China"},{"name":"Biomedical Engineering Department, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, Hubei 430074, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(04)00045-5"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(04)00045-5"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gki200"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.gde.2005.06.012"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1126\/science.1114519"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.2174\/092986710794182980"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6606010"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1002\/bies.201000040"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1186\/1476-4598-9-306"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1002\/path.2806"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1517\/14712598.2011.542749"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0003420"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkn714"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1039\/c2mb25180a"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1186\/1752-0509-4-S1-S2"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/204658"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1136\/amiajnl-2011-000419"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1038\/35002607"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1261\/rna.2183803"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm952"},{"key":"21","doi-asserted-by":"crossref","first-page":"309","DOI":"10.1098\/rsta.1922.0009","volume":"222","year":"1922","journal-title":"Philosophical Transactions of the Royal Society of London Series A"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1016\/j.compbiolchem.2012.02.004"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-11-S4-S5"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btq241"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2164-12-176"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.2460\/ajvr.73.10.1626"},{"key":"27","doi-asserted-by":"crossref","first-page":"723","DOI":"10.18632\/oncotarget.547","volume":"3","year":"2012","journal-title":"Oncotarget"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1007\/s12672-010-0041-7"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2012.02.020"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1016\/j.clgc.2012.01.001"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1111\/cbdd.12002"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.110.214478"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2940"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0035501"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1152\/physiolgenomics.00145.2011"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1002\/jso.23174"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2011.11.021"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1007\/s12032-012-0210-3"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgp250"},{"key":"40","first-page":"201","volume":"6","year":"2012","journal-title":"Molecular Medicine Reports"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0027840"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1021\/es201514h"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.3109\/15360288.2011.554488"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(11)70012-2"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0032068"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.3892\/or.2012.1719"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.4149\/neo_2012_087"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.3892\/ijo.2012.1342"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-09-2638"}],"container-title":["Computational and Mathematical Methods in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2014\/746979.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2014\/746979.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/cmmm\/2014\/746979.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,6,22]],"date-time":"2017-06-22T07:21:54Z","timestamp":1498116114000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/cmmm\/2014\/746979\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":49,"alternative-id":["746979","746979"],"URL":"https:\/\/doi.org\/10.1155\/2014\/746979","relation":{},"ISSN":["1748-670X","1748-6718"],"issn-type":[{"type":"print","value":"1748-670X"},{"type":"electronic","value":"1748-6718"}],"subject":[],"published":{"date-parts":[[2014]]}}}