{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T23:46:01Z","timestamp":1783467961513,"version":"3.55.0"},"reference-count":26,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Endocrinology"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Background.<\/jats:italic>Anaplastic thyroid cancer (ATC) is a form of thyroid cancer with very poor prognosis, but is fortunately quite rare. Its aetiology is unknown and not well researched.<jats:italic>Aim.<\/jats:italic>The aim of this study was to identify potential risk factors for ATC.<jats:italic>Material and Method.<\/jats:italic>Case-control study of 126 ATC patients (77 females and 49 males) and 252 controls individually matched by gender, age, and place of abode. In statistical analysis we used a Cox regression model.<jats:italic>Results.<\/jats:italic>Univariate logistic regression showed that the risk factors for ATC are low education level, type B blood group, goitre, other nonthyroid malignancies, diabetes, late menarche, and an early first pregnancy. Multivariate logistic regression analysis showed that independent risk factors for ATC are low education level (OR\u2009=\u20091.42, 95% CI\u2009=\u20091.09\u20131.86), type B blood group (OR\u2009=\u20092.41, 95% CI\u2009=\u20091.03\u20135.66), and goitre (OR\u2009=\u200925\u201333, 95% CI\u2009=\u20095.66\u2013126.65).<jats:italic>Conclusion.<\/jats:italic>Independent risk factors for ATC are: low education level, type B blood group, and goitre.<\/jats:p>","DOI":"10.1155\/2014\/815070","type":"journal-article","created":{"date-parts":[[2014,5,18]],"date-time":"2014-05-18T21:08:54Z","timestamp":1400447334000},"page":"1-6","source":"Crossref","is-referenced-by-count":11,"title":["Risk Factors for Anaplastic Thyroid Cancer"],"prefix":"10.1155","volume":"2014","author":[{"given":"V.","family":"Zivaljevic","sequence":"first","affiliation":[{"name":"Centre for Endocrine Surgery, Clinical Centre of Serbia, Koste Todorovica 8, 11000 Belgrade, Serbia"},{"name":"School of Medicine, University 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