{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,6]],"date-time":"2026-10-06T02:10:42Z","timestamp":1791252642854,"version":"4.1.0"},"reference-count":20,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Aim.<\/jats:italic>Feasibility and reliability of tissue Doppler imaging-(TDI-) based elastography for cervical quantitative stiffness assessment during all three trimesters of pregnancy were evaluated.<jats:italic>Materials and Methods.<\/jats:italic>Prospective case-control study including seventy-four patients collected between the 12th and 42nd weeks of gestation. The tissue strain (TS) was measured by two independent operators as natural strain. Intra- and interoperator intraclass correlation coefficient (ICC) agreements were evaluated.<jats:italic>Results.<\/jats:italic>TS measurement was always feasible and exhibited a high performance in terms of reliability (intraoperator ICC-agreement = 0.93; interoperator ICC agreement = 0.89 and 0.93 for a single measurement and for the average of two measurements, resp.). Cervical TS showed also a significant correlation with gestational age, cervical length, and parity.<jats:italic>Conclusions.<\/jats:italic>TS measurement during pregnancy demonstrated high feasibility and reliability. Furthermore, TS significantly correlated with gestational age, cervical length, and parity.<\/jats:p>","DOI":"10.1155\/2014\/826535","type":"journal-article","created":{"date-parts":[[2014,3,9]],"date-time":"2014-03-09T09:25:54Z","timestamp":1394357154000},"page":"1-9","source":"Crossref","is-referenced-by-count":33,"title":["Quantitative Elastography for Cervical Stiffness Assessment during Pregnancy"],"prefix":"10.1155","volume":"2014","author":[{"given":"A.","family":"Fruscalzo","sequence":"first","affiliation":[{"name":"Obstetrics and Gynecology, Mathias-Spital Rheine, Frankenburgstra\u00dfe 31, 48431 Rheine, Germany"},{"name":"Obstetrics and Gynecology, St. Franziskus Hospital, Hohenzollernring 72, 48145 M\u00fcnster, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. P.","family":"Londero","sequence":"additional","affiliation":[{"name":"Clinic of Obstetrics and Gynecology, University Hospital of Udine, University of Udine, P.le S. M. 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