{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T21:03:19Z","timestamp":1740171799953,"version":"3.37.3"},"reference-count":131,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Disease Markers"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Inflammatory mediators appear to be the most intriguing yet confusing subject, regarding the management of patients with acute coronary syndromes (ACS). The current inflammatory concept of atherosclerotic coronary artery disease (CAD) led many investigators to concentrate on systemic markers of inflammation, as well as imaging techniques, which may be helpful in risk stratification and prognosis assessment for cardiovascular events. In this review, we try to depict many of the recently studied markers regarding stable angina (SA), their clinical usefulness, and possible future applications in the field.<\/jats:p>","DOI":"10.1155\/2014\/831364","type":"journal-article","created":{"date-parts":[[2014,6,19]],"date-time":"2014-06-19T21:06:43Z","timestamp":1403212003000},"page":"1-14","source":"Crossref","is-referenced-by-count":5,"title":["Clinical Usefulness of Novel Serum and Imaging Biomarkers in Risk Stratification of Patients with Stable Angina"],"prefix":"10.1155","volume":"2014","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8927-9631","authenticated-orcid":true,"given":"George","family":"Tsaknis","sequence":"first","affiliation":[{"name":"Department of Respiratory Medicine, Glenfield Hospital, University Hospitals of Leicester, Groby Road, Leicester LE3 9QP, UK"},{"name":"Second Department of Critical Care Medicine, Attikon University Hospital, University of Athens, Medical School, 1 Rimini Street, Haidari, 12462 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4395-0471","authenticated-orcid":true,"given":"Iraklis","family":"Tsangaris","sequence":"additional","affiliation":[{"name":"Department of Respiratory Medicine, Glenfield Hospital, University Hospitals of Leicester, Groby Road, Leicester LE3 9QP, UK"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ignatios","family":"Ikonomidis","sequence":"additional","affiliation":[{"name":"Second Department of Cardiology, Attikon University Hospital, University of Athens, Medical School, 1 Rimini Street, Haidari, 12462 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Argirios","family":"Tsantes","sequence":"additional","affiliation":[{"name":"Laboratory of Haematology and Blood Bank Unit, Attikon University Hospital, University of Athens, Medical School, 1 Rimini Street, Haidari, 12462 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1"},{"year":"2006","key":"2"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.38695.605440.AE"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/eht533"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1161\/CIR.0b013e3182776f83"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehl001"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1111\/eci.12025"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.104.504159"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1001\/jama.294.3.326"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1097\/MCA.0b013e328332a6b0"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.dci.2003.09.007"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.106.650846"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCGENETICS.108.824870"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehm465"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.697714"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2011.173310"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1358\/dnp.2009.22.4.1367710"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2009.04.032"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.08.011"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1161\/hc0902.104353"},{"issue":"8","key":"22","doi-asserted-by":"crossref","first-page":"793","DOI":"10.1161\/01.CIR.100.8.793","volume":"100","year":"1999","journal-title":"Circulation"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.2174\/1874192401105010110"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000095270.85646.E8"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2003.07.014"},{"issue":"7","key":"26","doi-asserted-by":"crossref","first-page":"746","DOI":"10.1161\/hc3201.094973","volume":"104","year":"2001","journal-title":"Circulation"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn331"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1038\/nm.2106"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20092243"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.108.182428"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.1172\/JCI31344"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.111.224709"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2008.10.028"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C600011200"},{"issue":"8","key":"36","first-page":"CR406","volume":"14","year":"2008","journal-title":"Medical Science Monitor"},{"key":"37","first-page":"409","volume":"14","year":"2006","journal-title":"Netherlands Heart Journal"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.03.033"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000042674.89762.20"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa012295"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2362.2007.01908.x"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2009.09.026"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.02.040"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn071"},{"issue":"3","key":"45","doi-asserted-by":"crossref","first-page":"862","DOI":"10.1177\/147323000903700331","volume":"37","year":"2009","journal-title":"Journal of International Medical Research"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1080\/14017430600925300"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2007.10.017"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.1016\/j.cca.2011.10.009"},{"key":"50","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2004.08.018"},{"issue":"1","key":"51","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1189\/jlb.71.1.1","volume":"71","year":"2002","journal-title":"Journal of Leukocyte Biology"},{"issue":"6","key":"52","doi-asserted-by":"crossref","first-page":"425","DOI":"10.2298\/VSP0806425B","volume":"65","year":"2008","journal-title":"Vojnosanitetski Pregled"},{"key":"54","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2011.07.003"},{"key":"57","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2010.03.090"},{"key":"58","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2008.01.009"},{"key":"59","doi-asserted-by":"publisher","DOI":"10.1097\/01.mca.0000236288.94553.b4"},{"key":"60","doi-asserted-by":"publisher","DOI":"10.1038\/nm1400"},{"issue":"12","key":"53","first-page":"1357","volume":"26","year":"2007","journal-title":"Revista Portuguesa de Cardiologia"},{"key":"61","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2009.02.013"},{"key":"62","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.107.714691"},{"key":"63","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2011.09.022"},{"key":"64","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehi628"},{"key":"65","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2011.04547.x"},{"key":"66","doi-asserted-by":"publisher","DOI":"10.1097\/CCM.0b013e3181f17bf9"},{"issue":"7","key":"67","first-page":"823","volume":"78","year":"2012","journal-title":"Minerva Anestesiologica"},{"key":"68","doi-asserted-by":"publisher","DOI":"10.2143\/AC.62.2.2020233"},{"issue":"1","key":"69","doi-asserted-by":"crossref","first-page":"52","DOI":"10.1177\/147323001003800106","volume":"38","year":"2010","journal-title":"Journal of International Medical Research"},{"key":"70","doi-asserted-by":"publisher","DOI":"10.1080\/17482940701534800"},{"key":"71","doi-asserted-by":"publisher","DOI":"10.3109\/13547501003675084"},{"key":"72","doi-asserted-by":"publisher","DOI":"10.1253\/circj.CJ-10-0638"},{"key":"73","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199901143400207"},{"key":"74","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.814418"},{"key":"75","doi-asserted-by":"publisher","DOI":"10.2169\/internalmedicine.49.3223"},{"key":"76","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2006.084947"},{"key":"77","doi-asserted-by":"publisher","DOI":"10.3233\/DMA-130976"},{"issue":"12","key":"78","doi-asserted-by":"crossref","first-page":"2909","DOI":"10.1161\/01.ATV.19.12.2909","volume":"19","year":"1999","journal-title":"Arteriosclerosis, Thrombosis, and Vascular Biology"},{"key":"79","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000160551.21962.a7"},{"key":"80","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199511163332001"},{"key":"81a","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200010193431603"},{"key":"81b","doi-asserted-by":"publisher","DOI":"10.1161\/ATVBAHA.107.151670"},{"key":"82","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.108.771899"},{"key":"83","doi-asserted-by":"publisher","DOI":"10.2174\/157488711795177903"},{"key":"84","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2007.11.079"},{"issue":"3","key":"85","doi-asserted-by":"crossref","first-page":"251","DOI":"10.1161\/res.90.3.251","volume":"90","year":"2002","journal-title":"Circulation Research"},{"key":"86","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000135588.65188.14"},{"key":"87","doi-asserted-by":"publisher","DOI":"10.1016\/j.pcad.2009.12.002"},{"issue":"10","key":"88","doi-asserted-by":"crossref","first-page":"1214","DOI":"10.2174\/1568026611208011214","volume":"12","year":"2012","journal-title":"Current Topics in Medicinal Chemistry"},{"issue":"10","key":"89","doi-asserted-by":"crossref","first-page":"1192","DOI":"10.2174\/1568026611208011192","volume":"12","year":"2012","journal-title":"Current Topics in Medicinal Chemistry"},{"issue":"10","key":"90","doi-asserted-by":"crossref","first-page":"1166","DOI":"10.2174\/1568026611208011166","volume":"12","year":"2012","journal-title":"Current Topics in Medicinal Chemistry"},{"issue":"10","key":"91","doi-asserted-by":"crossref","first-page":"1132","DOI":"10.2174\/1568026611208011132","volume":"12","year":"2012","journal-title":"Current Topics in Medicinal Chemistry"},{"key":"92","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehq390"},{"key":"93","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0019340"},{"key":"94","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2006.09.001"},{"key":"95","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.10.013"},{"key":"96","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2009.07.037"},{"key":"97","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.0000191633.52585.14"},{"key":"98","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2007.05.011"},{"key":"99","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2005.03.072"},{"key":"100","doi-asserted-by":"publisher","DOI":"10.1016\/j.trsl.2011.11.002"},{"key":"101","doi-asserted-by":"publisher","DOI":"10.1024\/1661-8157\/a000837"},{"key":"102","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-10-7"},{"key":"103","doi-asserted-by":"publisher","DOI":"10.1016\/j.resuscitation.2011.12.015"},{"issue":"3","key":"104","first-page":"203","volume":"59","year":"2011","journal-title":"Minerva Cardioangiologica"},{"issue":"2","key":"105","first-page":"229","volume":"15","year":"2011","journal-title":"European Review for Medical and Pharmacological Sciences"},{"key":"106","doi-asserted-by":"publisher","DOI":"10.1016\/S0300-2896(10)70024-7"},{"key":"107","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2010.06.010"},{"key":"108","doi-asserted-by":"publisher","DOI":"10.4414\/smw.2010.13101"},{"key":"109","doi-asserted-by":"publisher","DOI":"10.1111\/j.1751-7133.2010.00177.x"},{"key":"110","doi-asserted-by":"publisher","DOI":"10.1186\/1741-7015-8-34"},{"key":"112","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2011.12.105"},{"key":"113","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2009.09.032"},{"key":"114","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(04)00045-5"},{"issue":"17","key":"115","doi-asserted-by":"crossref","first-page":"2127","DOI":"10.4161\/cc.6.17.4641","volume":"6","year":"2007","journal-title":"Cell Cycle"},{"issue":"20","key":"116","doi-asserted-by":"crossref","first-page":"3143","DOI":"10.4161\/cc.7.20.6833","volume":"7","year":"2008","journal-title":"Cell Cycle"},{"key":"117","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2008.274"},{"key":"118","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1209912"},{"key":"119","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2763"},{"key":"120","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.12.027"},{"key":"121","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2010.03.010"},{"key":"122","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.889048"},{"issue":"6","key":"123","first-page":"419","volume":"6","year":"2009","journal-title":"Nature Reviews"},{"key":"124","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0080345"},{"key":"125","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000034670.06526.15"},{"key":"126","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000155233.67287.60"},{"key":"127","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCINTERVENTIONS.108.847954"},{"key":"128","doi-asserted-by":"publisher","DOI":"10.1001\/jama.288.21.2693"},{"key":"129","doi-asserted-by":"crossref","first-page":"452","DOI":"10.1016\/j.ahj.2014.01.003","volume":"167","year":"2014","journal-title":"American Heart Journal"},{"key":"130","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-013-2539-z"},{"key":"131","doi-asserted-by":"publisher","DOI":"10.1093\/ehjci\/jeu027"},{"key":"132","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcct.2012.06.002"},{"issue":"16","key":"133","doi-asserted-by":"crossref","first-page":"1515","DOI":"10.1016\/j.jacc.2009.05.065","volume":"54","year":"2009","journal-title":"Journal of the American College of Cardiology"},{"key":"134","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.0000015464.18023.0A"},{"key":"135","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2013.11.070"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjmed.2011.02.040"}],"container-title":["Disease Markers"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/dm\/2014\/831364.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/dm\/2014\/831364.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/dm\/2014\/831364.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,7,14]],"date-time":"2023-07-14T12:20:44Z","timestamp":1689337244000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/dm\/2014\/831364\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":131,"alternative-id":["831364","831364"],"URL":"https:\/\/doi.org\/10.1155\/2014\/831364","relation":{},"ISSN":["0278-0240","1875-8630"],"issn-type":[{"type":"print","value":"0278-0240"},{"type":"electronic","value":"1875-8630"}],"subject":[],"published":{"date-parts":[[2014]]}}}