{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T22:31:22Z","timestamp":1777501882059,"version":"3.51.4"},"reference-count":15,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,7,1]],"date-time":"2014-07-01T00:00:00Z","timestamp":1404172800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Scholarly Research Notices"],"published-print":{"date-parts":[[2014,7,1]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To investigate serum levels of free <jats:italic>\u03b2<\/jats:italic>-HCG, progesterone, and ischemia-modified albumin (IMA) and their combined use in the prediction of first trimester abortions. <jats:italic>Methods<\/jats:italic>. A total of 156 pregnant women between 5 and 13 weeks of gestational age were included in this study. At admission, serum levels of free <jats:italic>\u03b2<\/jats:italic>-HCG, progesterone, and IMA were noted and all cases were divided into two groups; Group I (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>77<\/mml:mn><\/mml:math>) resulted in abortion including missed abortion, incomplete\/complete abortion, and inevitable abortion whereas Group II (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>79<\/mml:mn><\/mml:math>) included normal pregnancies. <jats:italic>Results<\/jats:italic>. Compared to Group II, the significantly decreased value of free <jats:italic>\u03b2<\/jats:italic>-HCG progesterone and significantly increased value of IMA were found in Group I (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.01<\/mml:mn><\/mml:math>, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.01<\/mml:mn><\/mml:math>, <mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.01<\/mml:mn><\/mml:math>, resp.). When combining all three parameters, sensitivity 75%, specificity 99%, PPV 98%, and NPV 76% were obtained. The multivariate logistic regression analysis revealed the free <jats:italic>\u03b2<\/jats:italic>-HCG, progesterone, and IMA independent factors in the prediction of abortions. <jats:italic>Conclusions<\/jats:italic>. The combined use of free <jats:italic>\u03b2<\/jats:italic>-HCG, progesterone, and IMA levels can be useful in the prediction of first trimester spontaneous abortions.<\/jats:p>","DOI":"10.1155\/2014\/846531","type":"journal-article","created":{"date-parts":[[2014,7,2]],"date-time":"2014-07-02T08:55:55Z","timestamp":1404291355000},"page":"1-5","source":"Crossref","is-referenced-by-count":3,"title":["The Diagnostic Value of <i>\u03b2<\/i>-Human Chorionic Gonadotropin, Progesterone, and Ischemia-Modified Albumin and Their Combined Use in the Prediction of First Trimester Abortions"],"prefix":"10.1155","volume":"2014","author":[{"given":"Mehmet A.","family":"Osmana\u011fao\u011flu","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine, Karadeniz Technical University, 61080 Trabzon, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S. Caner","family":"Karahan","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Medicine, Karadeniz Technical University, 61080 Trabzon, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Turhan","family":"Aran","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine, Karadeniz Technical University, 61080 Trabzon, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"S\u00fcleyman","family":"G\u00fcven","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine, Karadeniz Technical University, 61080 Trabzon, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Elif","family":"Turgut","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine, Karadeniz Technical University, 61080 Trabzon, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ahmet","family":"Mente\u015fe","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Faculty of Medicine, Karadeniz Technical University, 61080 Trabzon, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hasan","family":"Bozkaya","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Faculty of Medicine, Karadeniz Technical University, 61080 Trabzon, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1080\/10641950701885147"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1080\/00016340902777517"},{"key":"3","doi-asserted-by":"crossref","first-page":"418","DOI":"10.3109\/14767058.2010.497879","volume":"24","year":"2011","journal-title":"Journal of Maternal-Fetal and Neonatal Medicine"},{"issue":"3","key":"4","doi-asserted-by":"crossref","first-page":"222","DOI":"10.1046\/j.1525-1373.1999.d01-139.x","volume":"222","year":"1999","journal-title":"Proceedings of the Society for Experimental Biology and Medicine"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1093\/humrep\/den029"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1155\/2008\/523081"},{"key":"7","doi-asserted-by":"crossref","first-page":"209","DOI":"10.1016\/j.ejogrb.2010.12.004","volume":"155","year":"2011","journal-title":"The European Journal of Obstetrics & Gynecology and Reproductive Biology"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.3109\/01443611003605286"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/S0736-4679(00)00255-9"},{"issue":"1","key":"9","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/0378-3782(87)90099-5","volume":"15","year":"1987","journal-title":"Early Human Development"},{"issue":"4","key":"10","doi-asserted-by":"crossref","first-page":"881","DOI":"10.1093\/oxfordjournals.humrep.a019271","volume":"11","year":"1996","journal-title":"Human Reproduction"},{"issue":"2","key":"11","first-page":"89","volume":"49","year":"2004","journal-title":"The Journal of Reproductive Medicine"},{"issue":"2","key":"12","doi-asserted-by":"crossref","first-page":"380","DOI":"10.1016\/S0002-9378(94)70038-9","volume":"171","year":"1994","journal-title":"American Journal of Obstetrics and Gynecology"},{"issue":"5","key":"13","doi-asserted-by":"crossref","first-page":"622","DOI":"10.1093\/oxfordjournals.humrep.a137157","volume":"5","year":"1990","journal-title":"Human Reproduction"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2008.10.038"}],"container-title":["International Scholarly Research Notices"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/archive\/2014\/846531.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2014\/846531.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/archive\/2014\/846531.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,12,9]],"date-time":"2020-12-09T20:53:03Z","timestamp":1607547183000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/isrn\/2014\/846531\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,7,1]]},"references-count":15,"alternative-id":["846531","846531"],"URL":"https:\/\/doi.org\/10.1155\/2014\/846531","relation":{},"ISSN":["2356-7872"],"issn-type":[{"value":"2356-7872","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7,1]]}}}