{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,2]],"date-time":"2026-07-02T01:00:27Z","timestamp":1782954027825,"version":"3.54.5"},"reference-count":16,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>The main rationale of routine histopathologic examination of products after first-trimester miscarriages is to detect an ectopic pregnancy or a molar pregnancy, which require further management. An alternative approach is to examine the products only when there is a definite indication. As there is no agreement, we aimed to study whether routine histopathological examination of tissues obtained after first-trimester miscarriage is of any clinical value in our populations. Medical records of all (558) patients with a diagnosis of first-trimester miscarriage over 4 years (2007\u20132010) at King Abdulaziz University Hospital, Jeddah, Saudi Arabia, were reviewed. Histopathologic examination confirmed products of conception in 537 (96.2%) patients, no products of conception in 17 (3%) patients, molar pregnancy in 2 (0.4%) patients, and decidual tissues without chorionic villi (Arias-Stella reaction) in 2 (0.4%) patients. After clinical correlation, only one unsuspected partial molar pregnancy was diagnosed by histopathology examination. Conclusion is that it does not appear reasonable to perform histopathological examination routinely after all first-trimester miscarriages in our studied population. We recommend that histopathological examination be performed in select instances: when the diagnosis is uncertain, when fewer tissues have been obtained during surgery, when unexpected pathology was seen, when ultrasound suggests a molar pregnancy, or when patients are considered at high risk for trophoblastic disease.<\/jats:p>","DOI":"10.1155\/2014\/863482","type":"journal-article","created":{"date-parts":[[2014,6,26]],"date-time":"2014-06-26T21:05:45Z","timestamp":1403816745000},"page":"1-5","source":"Crossref","is-referenced-by-count":12,"title":["Value of Histopathologic Examination of Uterine Products after First-Trimester Miscarriage"],"prefix":"10.1155","volume":"2014","author":[{"given":"Sharifa Ali","family":"Alsibiani","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynaecology, Faculty of Medicine, King Abdulaziz University, P.O. Box 122413, Jeddah 21332, Saudi Arabia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"key":"1","volume-title":"First trimester abortion","year":"2008"},{"key":"2","year":"2006"},{"key":"3","year":"2012"},{"issue":"6","key":"4","doi-asserted-by":"crossref","first-page":"727","DOI":"10.1111\/j.1471-0528.2000.tb13332.x","volume":"107","year":"2000","journal-title":"British Journal of Obstetrics and Gynaecology"},{"key":"5","year":"2011"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/S0301-2115(02)00155-0"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/S0020-7292(02)00397-1"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1111\/j.1447-0756.2005.00341.x"},{"issue":"4","key":"9","first-page":"83","volume":"1","year":"2006","journal-title":"Tanta Medical Science Journal"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1002\/uog.3875"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1046\/j.0960-7692.2001.00589.x"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.a1193"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/S1521-6934(03)00049-X"},{"key":"15","doi-asserted-by":"crossref","first-page":"57","DOI":"10.4103\/2230-8229.99199","volume":"7","year":"2000","journal-title":"Journal of Family and Community Medicine"},{"issue":"12","key":"16","first-page":"1329","volume":"24","year":"2003","journal-title":"Saudi Medical Journal"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.4103\/2230-8229.90018"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2014\/863482.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2014\/863482.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2014\/863482.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,5,28]],"date-time":"2024-05-28T02:10:49Z","timestamp":1716862249000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/bmri\/2014\/863482\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":16,"alternative-id":["863482","863482"],"URL":"https:\/\/doi.org\/10.1155\/2014\/863482","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}