{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T19:23:12Z","timestamp":1789672992029,"version":"4.0.1"},"reference-count":14,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Pathogens"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>Frequently reported<jats:italic>H. pylori<\/jats:italic>antimicrobial therapy failures suggest that there might be a different niche where the bacteria can stay safe. Current study aims to examine potential role of oral colonization of<jats:italic>H. pylori<\/jats:italic>to feed reinfection after primary therapy. However, patients who were admitted to the gastroscopy section were chosen and gastric biopsy and dental plaque specimens were collected. Molecular and biochemical tests were applied to confirm<jats:italic>H. pylori<\/jats:italic>identity in different colonization niches. Results showed that 88.8% of dyspeptic patients had epigastric pains with nocturnal awakening when they were hungry (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.023<\/mml:mn><\/mml:math>). All patients who received therapy already were again H. pylori positive while they are still carrying<jats:italic>H. pylori<\/jats:italic>in dental plaque (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:math>). Moreover, H. pylori infection was sought in 100% of gastric biopsy\u2019s dyspeptic patients who had ulcerated esophagitis and erosive duodenitis and who were<jats:italic>H. pylori<\/jats:italic>positive, and 75% of dyspeptic patients with duodenum deformity had this bacterium in gastric biopsies (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.004<\/mml:mn><\/mml:math>). Present study showed that only successful eradication of gastric<jats:italic>H. pylori<\/jats:italic>cannot guarantee prevention of reinfection. Conclusively, a new strategy which indicates concomitant eradication in oral and gastric colonization can result in clearance of<jats:italic>H. pylori<\/jats:italic>infection.<\/jats:p>","DOI":"10.1155\/2014\/871601","type":"journal-article","created":{"date-parts":[[2014,7,9]],"date-time":"2014-07-09T21:09:14Z","timestamp":1404940154000},"page":"1-4","source":"Crossref","is-referenced-by-count":8,"title":["Concomitant Colonization of<i>Helicobacter pylori<\/i>in Dental Plaque and Gastric Biopsy"],"prefix":"10.1155","volume":"2014","author":[{"given":"Amin Talebi Bezmin","family":"Abadi","sequence":"first","affiliation":[{"name":"Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, P.O. Box 14115-111, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ashraf Mohabati","family":"Mobarez","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, P.O. Box 14115-111, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Omid","family":"Teymournejad","sequence":"additional","affiliation":[{"name":"Department of Microbiology, School of Medicine, University of Medical Science, Babol, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona","family":"Karbalaei","sequence":"additional","affiliation":[{"name":"Department of Bacteriology, Faculty of Medical Sciences, Tarbiat Modares University, P.O. Box 14115-111, Tehran, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00054-05"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2010.154"},{"issue":"3","key":"3","first-page":"523","volume":"7","year":"2014","journal-title":"International Journal of Clinical and Experimental Medicine"},{"issue":"3","key":"4","volume":"5","year":"2014","journal-title":"Gut Microbes"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1304681110"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/124607"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9270(00)02023-2"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1136\/jcp.53.3.218"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2005.01.012"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v20.i6.1438"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2004.11.037"},{"issue":"6","key":"12","doi-asserted-by":"crossref","first-page":"1397","DOI":"10.1128\/JCM.27.6.1397-1398.1989","volume":"27","year":"1989","journal-title":"Journal of Clinical Microbiology"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.3201\/eid1503.080850"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1097\/INF.0000000000000017"}],"container-title":["Journal of Pathogens"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/jpath\/2014\/871601.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jpath\/2014\/871601.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/jpath\/2014\/871601.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,22]],"date-time":"2020-08-22T03:41:01Z","timestamp":1598067661000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/jpath\/2014\/871601\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":14,"alternative-id":["871601","871601"],"URL":"https:\/\/doi.org\/10.1155\/2014\/871601","relation":{},"ISSN":["2090-3057","2090-3065"],"issn-type":[{"value":"2090-3057","type":"print"},{"value":"2090-3065","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}