{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,7,11]],"date-time":"2025-07-11T10:29:00Z","timestamp":1752229740136},"reference-count":32,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Behavioural Neurology"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p>We report a case of a 47-year-old woman with 35-year history of multiple sclerosis, who showed alien hand signs, a rare behavioural disorder that involves unilateral goal-directed movements that are contrary to the individual's intention. Alien hand syndrome has been described in multiple sclerosis (MS) only occasionally and is generally suggestive of callosal disconnection. The patient presented also with bilateral limb apraxia and left hand agraphia, raising the possibility of cortical dysfunction or disconnection, in addition to corpus callosum and white matter involvement. Her specific pattern of symptoms supports the role of the corpus callosum in interhemispheric communication for complex as well as fine motor activities and may indicate that it can serve as both an inhibitory and excitatory function depending on task demands.<\/jats:p>","DOI":"10.1155\/2014\/873541","type":"journal-article","created":{"date-parts":[[2014,2,18]],"date-time":"2014-02-18T21:04:21Z","timestamp":1392757461000},"page":"1-7","source":"Crossref","is-referenced-by-count":5,"title":["Intermittent Alien Hand Syndrome and Callosal Apraxia in Multiple Sclerosis: Implications for Interhemispheric Communication"],"prefix":"10.1155","volume":"2014","author":[{"given":"A.","family":"Lunardelli","sequence":"first","affiliation":[{"name":"Rehabilitation Medicine, Ospedali Riuniti, Trieste, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Sartori","sequence":"additional","affiliation":[{"name":"Department of Medical Sciences, University of Trieste, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Mengotti","sequence":"additional","affiliation":[{"name":"Neuroscience Area, SISSA, Trieste, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. I.","family":"Rumiati","sequence":"additional","affiliation":[{"name":"Neuroscience Area, SISSA, Trieste, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"V.","family":"Pesavento","sequence":"additional","affiliation":[{"name":"Rehabilitation Medicine, Ospedali Riuniti, Trieste, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"issue":"3","key":"1","doi-asserted-by":"crossref","first-page":"192","DOI":"10.1017\/S0317167100000834","volume":"27","year":"2000","journal-title":"Canadian Journal of Neurological Sciences"},{"issue":"12","key":"2","doi-asserted-by":"crossref","first-page":"2710","DOI":"10.1212\/WNL.43.12.2710","volume":"43","year":"1993","journal-title":"Neurology"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1002\/ana.21173"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.68.1.83"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1007\/s10072-003-0149-4"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/119.3.859"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1046\/j.1351-5101.2003.00734.x"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1097\/NRL.0b013e318172cf5e"},{"key":"25","year":"2001"},{"key":"11","first-page":"311","volume":"3","year":"2011","journal-title":"Ricerche di Psicologia"},{"key":"26","year":"2008"},{"key":"27","doi-asserted-by":"crossref","first-page":"41","DOI":"10.1016\/0028-3932(68)90037-7","volume":"6","year":"1968","journal-title":"Neuropsychologia"},{"key":"28","doi-asserted-by":"crossref","first-page":"1173","DOI":"10.1093\/brain\/111.5.1173","volume":"111","year":"1988","journal-title":"Brain"},{"key":"29","doi-asserted-by":"crossref","first-page":"378","DOI":"10.1159\/000117297","volume":"36","year":"1996","journal-title":"European Neurology"},{"key":"30","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s100720200003","volume":"22","year":"2002","journal-title":"Neurological Sciences"},{"key":"31","year":"1997"},{"key":"32","year":"2008"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(08)70259-X"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awm003"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-0404.2009.01221.x"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.bandc.2007.07.010"},{"issue":"6\u20138","key":"14","first-page":"645","volume":"15","year":"1998","journal-title":"Cognitive Neuropsychology"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2004.06.017"},{"key":"16","doi-asserted-by":"crossref","first-page":"675","DOI":"10.1212\/WNL.12.10.675","volume":"12","year":"1962","journal-title":"Neurology"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1080\/17470210701508798"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1006\/brcg.2000.1226"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1162\/0898929054985374"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuropsychologia.2010.04.025"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/S0028-3932(01)00062-8"},{"issue":"10","key":"22","doi-asserted-by":"crossref","first-page":"1888","DOI":"10.1212\/WNL.57.10.1888","volume":"57","year":"2001","journal-title":"Neurology"},{"issue":"2","key":"23","doi-asserted-by":"crossref","first-page":"161","DOI":"10.1212\/WNL.39.2.161","volume":"39","year":"1989","journal-title":"Neurology"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1007\/s11065-005-6252-y"}],"container-title":["Behavioural Neurology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bn\/2014\/873541.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bn\/2014\/873541.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bn\/2014\/873541.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,7]],"date-time":"2019-08-07T19:03:42Z","timestamp":1565204622000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/bn\/2014\/873541\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014]]},"references-count":32,"alternative-id":["873541","873541"],"URL":"https:\/\/doi.org\/10.1155\/2014\/873541","relation":{},"ISSN":["0953-4180","1875-8584"],"issn-type":[{"value":"0953-4180","type":"print"},{"value":"1875-8584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014]]}}}