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There is mounting evidence that probiotics are effective in the treatment of covert and overt hepatic encephalopathy, as well as in the prevention of recurrence of encephalopathy. The beneficial effect of probiotics also extends to liver function in cirrhosis, nonalcoholic fatty liver disease, and alcoholic liver disease. On the other hand, data associating probiotics and portal hypertension is scanty and conflicting. Probiotic therapy has also not been shown to prevent primary or secondary spontaneous bacterial peritonitis. Larger clinical studies are required before probiotics can be recommended as a treatment modality in liver diseases.<\/jats:p>","DOI":"10.1155\/2014\/874768","type":"journal-article","created":{"date-parts":[[2014,11,11]],"date-time":"2014-11-11T21:05:52Z","timestamp":1415739952000},"page":"1-7","source":"Crossref","is-referenced-by-count":21,"title":["Is There a Role for Probiotics in Liver Disease?"],"prefix":"10.1155","volume":"2014","author":[{"given":"Robert S.","family":"Lo","sequence":"first","affiliation":[{"name":"Liver Unit, Royal Derby Hospital, Derby DE22 3NE, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew S.","family":"Austin","sequence":"additional","affiliation":[{"name":"Liver Unit, Royal Derby Hospital, Derby DE22 3NE, UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan G.","family":"Freeman","sequence":"additional","affiliation":[{"name":"Liver Unit, Royal Derby Hospital, Derby DE22 3NE, 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