{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,2,21]],"date-time":"2025-02-21T20:28:33Z","timestamp":1740169713049,"version":"3.37.3"},"reference-count":20,"publisher":"Wiley","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"The National Research Council and Department of Science and Technology of the Brazilian Ministry of Health","award":["402702\/2008-5"],"award-info":[{"award-number":["402702\/2008-5"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Objective.<\/jats:italic>To assess occurrence of severe maternal complications associated with ectopic pregnancy (EP).<jats:italic>Method.<\/jats:italic>A multicenter cross-sectional study was conducted, with prospective surveillance of potentially life-threatening conditions (PLTC), maternal near miss (MNM), and maternal death (MD). EP complications, patient sociodemographic\/obstetric characteristics, and conditions of severity management were assessed, estimating prevalence ratios with respective 95% CI. Factors independently associated with greater severity were identified using multiple regression analysis.<jats:italic>Results.<\/jats:italic>Of the 9.555 severe maternal morbidity patients, 312 women (3.3%) had complications after EP: 286 (91.7%) PLTC, 25 (8.0%) MNM, and 1 (0.3%) MD. Severe maternal outcome ratio (SMOR) was 0.3\/1000\u2009LB among EP cases and 10.8\/1000\u2009LB among other causes. Complicated EP patients faced a higher risk of blood transfusion, laparotomy, and lower risk of ICU admission and prolonged hospitalization than women developing complications resulting from other causes. Substandard care was the most common in more severe maternal morbidity and EP cases (22.7% MNM and MD versus 15% PLTC), although not significant.<jats:italic>Conclusion.<\/jats:italic>Increased maternal morbidity due to EP raised awareness about the condition and its impact on female reproductive life. No important risk factors for greater severity were identified. Care providers should develop specific guidelines and interventions to prevent severe maternal morbidity.<\/jats:p>","DOI":"10.1155\/2014\/965724","type":"journal-article","created":{"date-parts":[[2014,3,19]],"date-time":"2014-03-19T23:04:05Z","timestamp":1395270245000},"page":"1-8","source":"Crossref","is-referenced-by-count":0,"title":["Awareness about a Life-Threatening Condition: Ectopic Pregnancy in a Network for Surveillance of Severe Maternal Morbidity in Brazil"],"prefix":"10.1155","volume":"2014","author":[{"given":"Edilberto Alves Rocha","family":"Filho","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine, State University of Campinas, R. Alexander Fleming 101, 13083-881 Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Danielly Scaranello","family":"Santana","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine, State University of Campinas, R. Alexander Fleming 101, 13083-881 Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1285-8445","authenticated-orcid":true,"given":"Jose Guilherme","family":"Cecatti","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine, State University of Campinas, R. Alexander Fleming 101, 13083-881 Campinas, SP, Brazil"},{"name":"Campinas Center for Studies in Reproductive Health (CEMICAMP), R. Vital Brasil 200, 13083-888 Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Laura","family":"Costa","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine, State University of Campinas, R. Alexander Fleming 101, 13083-881 Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samira Maerrawe","family":"Haddad","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine, State University of Campinas, R. Alexander Fleming 101, 13083-881 Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary Angela","family":"Parpinelli","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine, State University of Campinas, R. Alexander Fleming 101, 13083-881 Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Maria Helena","family":"Sousa","sequence":"additional","affiliation":[{"name":"Campinas Center for Studies in Reproductive Health (CEMICAMP), R. Vital Brasil 200, 13083-888 Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodrigo Soares","family":"Camargo","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine, State University of Campinas, R. Alexander Fleming 101, 13083-881 Campinas, SP, Brazil"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rodolfo Carvalho","family":"Pacagnella","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, School of Medicine, State University of Campinas, R. 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