{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T02:02:26Z","timestamp":1773280946593,"version":"3.50.1"},"reference-count":18,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2014,1,1]],"date-time":"2014-01-01T00:00:00Z","timestamp":1388534400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2014]]},"abstract":"<jats:p><jats:italic>Purpose<\/jats:italic>. To evaluate the depth of corneal stromal demarcation line using AS-OCT and confocal microscopy after two different protocols of accelerated corneal collagen cross-linking procedures (CXL).<jats:italic>Methods<\/jats:italic>. Patients with keratoconus were divided into two groups. Peschke CXL device (Peschke CCL-VARIO Meditrade GmbH) applied UVA light with an intended irradiance of 18.0\u2009mW\/cm<jats:sup>2<\/jats:sup>for 5 minutes after applying riboflavin for 20 minutes (group 1) and 30 minutes (group 2). One month postoperatively, corneal stromal demarcation line was measured using AS-OCT and confocal microscopy.<jats:italic>Results<\/jats:italic>. This study enrolled 34 eyes of 34 patients (17 eyes in group 1 and 17 eyes in group 2). The mean depth of the corneal stromal demarcation line was<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mn>208.64<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>18.41<\/mml:mn><\/mml:math>\u2009<jats:italic>\u03bc<\/jats:italic>m in group 1 and<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mn>240.37<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>18.89<\/mml:mn><\/mml:math>\u2009<jats:italic>\u03bc<\/jats:italic>m in group 2 measured with AS OCT, while it was<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mn>210.29<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>18.66<\/mml:mn><\/mml:math>\u2009<jats:italic>\u03bc<\/jats:italic>m in group 1 and<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mn>239.37<\/mml:mn><mml:mo>\u00b1<\/mml:mo><mml:mn>20.07<\/mml:mn><\/mml:math>\u2009<jats:italic>\u03bc<\/jats:italic>m in group 2 measured with confocal microscopy. Corneal stromal demarcation line depth measured with AS OCT or confocal microscopy was significantly deeper in group 2 than group 1<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mo stretchy=\"false\">(<\/mml:mo><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.01<\/mml:mn><mml:mo stretchy=\"false\">)<\/mml:mo><\/mml:math>.<jats:italic>Conclusion<\/jats:italic>. The group in which riboflavin was applied for 30 minutes showed significantly deeper corneal stromal demarcation line than the group in which riboflavin was applied for 20 minutes.<\/jats:p>","DOI":"10.1155\/2014\/981893","type":"journal-article","created":{"date-parts":[[2014,11,18]],"date-time":"2014-11-18T21:06:38Z","timestamp":1416344798000},"page":"1-5","source":"Crossref","is-referenced-by-count":27,"title":["Evaluation of Corneal Stromal Demarcation Line after Two Different Protocols of Accelerated Corneal Collagen Cross-Linking Procedures Using Anterior Segment Optical Coherence Tomography and Confocal Microscopy"],"prefix":"10.1155","volume":"2014","author":[{"given":"Engin Bilge","family":"Ozgurhan","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, Beyoglu Eye Training and Research Hospital, Bereketzade Camii Sok, Kuledibi, Beyoglu, 34421 Istanbul, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Betul Ilkay","family":"Sezgin 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