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To date, no ideal treatment method has been established. Meanwhile, the underlying mechanism of hypertrophic scarring has not been clearly defined. Although a large amount of scientific research has been reported on the use of medicinal plants as a natural source of treatment for hypertrophic scarring, it is currently scattered across a wide range of publications. Therefore, a systematic summary and knowledge for future prospects are necessary to facilitate further medicinal plant research for their potential use as antihypertrophic scar agents. A bibliographic investigation was accomplished by focusing on medicinal plants which have been scientifically tested<jats:italic>in vitro<\/jats:italic>and\/or<jats:italic>in vivo<\/jats:italic>and proved as potential agents for the treatment of hypertrophic scars. Although the chemical components and mechanisms of action of medicinal plants with antihypertrophic scarring potential have been investigated, many others remain unknown. More investigations and clinical trials are necessary to make use of these medical plants reasonably and phytotherapy is a promising therapeutic approach against hypertrophic scars.<\/jats:p>","DOI":"10.1155\/2015\/101340","type":"journal-article","created":{"date-parts":[[2015,3,11]],"date-time":"2015-03-11T17:01:42Z","timestamp":1426093302000},"page":"1-15","source":"Crossref","is-referenced-by-count":20,"title":["Medicinal Plants for the Treatment of Hypertrophic Scars"],"prefix":"10.1155","volume":"2015","author":[{"given":"Qi","family":"Ye","sequence":"first","affiliation":[{"name":"College of Life Science, Fujian Agriculture and Forestry University, Fuzhou 350002, China"},{"name":"Department of Pharmaceutical Botany, School of Pharmacy, Second Military Medical University, Shanghai 200433, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Su-Juan","family":"Wang","sequence":"additional","affiliation":[{"name":"Central Laboratory, Shanghai Seventh People\u2019s 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