{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,6,24]],"date-time":"2023-06-24T11:15:31Z","timestamp":1687605331461},"reference-count":35,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["International Journal of Chronic Diseases"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To study whether mean platelet volume (MPV) and splenomegaly could be used as subclinical inflammatory markers in children with familial Mediterranean fever (FMF) at the attack-free period.<jats:italic>Patients and Methods<\/jats:italic>. The study included ninety-seven children with FMF. MPV was carried out within 4 hours of blood sampling according to standard laboratory practice. Splenomegaly was determined by abdominal ultrasound (USG).<jats:italic>Results<\/jats:italic>. High MPV was detected in 84.45% of our studied patients and was significantly higher in FMF patients with splenomegaly than in patients without splenomegaly. There was a statistically significant correlation between MPV and splenic span (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.045<\/mml:mn><\/mml:math>).<jats:italic>Conclusion<\/jats:italic>. Elevated MPV and its significant correlation with splenic span in FMF children during the attack-free periods support the use of MPV and splenomegaly as useful markers of the subclinical inflammation in FMF patients at the attack-free period.<\/jats:p>","DOI":"10.1155\/2015\/152616","type":"journal-article","created":{"date-parts":[[2015,7,13]],"date-time":"2015-07-13T21:03:49Z","timestamp":1436821429000},"page":"1-6","source":"Crossref","is-referenced-by-count":4,"title":["Mean Platelet Volume and Splenomegaly as Useful Markers of Subclinical Activity in Egyptian Children with Familial Mediterranean Fever: A Cross-Sectional Study"],"prefix":"10.1155","volume":"2015","author":[{"given":"Huda","family":"Marzouk","sequence":"first","affiliation":[{"name":"Department of Pediatrics, Faculty of Medicine, Cairo University, Cairo 11562, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hala M.","family":"Lotfy","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Faculty of Medicine, Cairo University, Cairo 11562, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yomna","family":"Farag","sequence":"additional","affiliation":[{"name":"Department of Pediatrics, Faculty of Medicine, Cairo University, Cairo 11562, Egypt"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"L. 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