{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T14:25:54Z","timestamp":1791987954535,"version":"4.4.0"},"reference-count":15,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003593","name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","doi-asserted-by":"publisher","award":["470153\/2011-3"],"award-info":[{"award-number":["470153\/2011-3"]}],"id":[{"id":"10.13039\/501100003593","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Evidence-Based Complementary and Alternative Medicine"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Upon undergoing biomonitoring, the most active dichloromethane extract retrieved from<jats:italic>Senna macranthera<\/jats:italic>roots led to the isolation of three main compounds: emodine, physione, and chrysophanol. In this sequence, these compounds revealed a potential antibacterial activity against<jats:italic>Staphylococcus aureus<\/jats:italic>strains isolated from animals with mastitis infections with minimum inhibitory concentration (MIC) values of 20, 90, and 90\u2009<jats:italic>\u03bc<\/jats:italic>g\u2009mL<jats:sup>\u22121<\/jats:sup>, respectively. Therefore, an herbal soap was also produced from this same active extract. This soap was tested<jats:italic>in vitro<\/jats:italic>using gloves contaminated by animals with bovine mastitis that had been discarded after use by milkers and showed similar results to previously tested compounds. These results indicate the potential of this plant as an alternative veterinary medicine for the production of antibacterial soaps that aimed at controlling bovine mastitis infections in small Brazilian farms.<\/jats:p>","DOI":"10.1155\/2015\/217598","type":"journal-article","created":{"date-parts":[[2015,3,3]],"date-time":"2015-03-03T21:01:02Z","timestamp":1425416462000},"page":"1-6","source":"Crossref","is-referenced-by-count":9,"title":["Chemical Constituents and an Alternative Medicinal Veterinary Herbal Soap Made from<i>Senna macranthera<\/i>"],"prefix":"10.1155","volume":"2015","author":[{"given":"Fl\u00e1via","family":"Inoue Andrade","sequence":"first","affiliation":[{"name":"Departamento de Bioqu\u00edmica e Biologia Molecular, Universidade Federal de Vi\u00e7osa, 36570-000 Vi\u00e7osa, MG, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gislaine Aparecida","family":"Purgato","sequence":"additional","affiliation":[{"name":"Departamento de Bioqu\u00edmica 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