{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,6]],"date-time":"2026-04-06T21:32:34Z","timestamp":1775511154147,"version":"3.50.1"},"reference-count":9,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. Intrathoracic lymphadenopathy (LAD) in patients with Human Immunodeficiency Virus (HIV) infection is common, with wide-ranging diagnoses, from benign to malignant causes. Endobronchial Ultrasound-guided Transbronchial Needle Aspiration (EBUS-TBNA) is a relatively new technology with established applications in lung cancer, sarcoidosis, and tuberculosis. We sought to find out whether the addition of EBUS-TBNA to the diagnostic algorithm for LAD in HIV patients will reduce the need for mediastinoscopy.<jats:italic>Methods<\/jats:italic>. Retrospective chart review of all EBUS-TBNA procedures performed in our centre from August 2008 to December 2012.<jats:italic>Results<\/jats:italic>. 513 patients had EBUS-TBNA performed during this period. We identified nine HIV-infected patients who had LAD of unknown cause and underwent EBUS-TBNA. The procedure reduced the need for mediastinoscopy in eight patients (89%).<jats:italic>Conclusions<\/jats:italic>. Potential mediastinoscopies can be avoided by utilising EBUS-TBNA in HIV patients with LAD.<\/jats:p>","DOI":"10.1155\/2015\/257932","type":"journal-article","created":{"date-parts":[[2015,1,14]],"date-time":"2015-01-14T16:01:04Z","timestamp":1421251264000},"page":"1-5","source":"Crossref","is-referenced-by-count":1,"title":["Utility of Endobronchial Ultrasound-Guided Transbronchial Needle Aspiration in Diagnosis of Intrathoracic Lymphadenopathy in Patients with Human Immunodeficiency Virus Infection"],"prefix":"10.1155","volume":"2015","author":[{"given":"Audrey Yan Yi","family":"Han","sequence":"first","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Singapore General Hospital, 20 College Road, Academia, Singapore 169856"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7019-4766","authenticated-orcid":true,"given":"Aik Hau","family":"Tan","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Singapore General Hospital, 20 College Road, Academia, Singapore 169856"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariko Siyue","family":"Koh","sequence":"additional","affiliation":[{"name":"Department of Respiratory and Critical Care Medicine, Singapore General Hospital, 20 College Road, Academia, Singapore 169856"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/00126334-200211010-00004"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1080\/00313020701230674"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.athoracsur.2006.05.023"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.157.6.9607093"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1001\/jama.299.5.540"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1378\/chest.08-2768"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1136\/thoraxjnl-2011-200063"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.56.suppl_1.i1"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1186\/1465-9921-14-50"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/257932.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/257932.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/257932.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,7,27]],"date-time":"2016-07-27T09:10:07Z","timestamp":1469610607000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/bmri\/2015\/257932\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":9,"alternative-id":["257932","257932"],"URL":"https:\/\/doi.org\/10.1155\/2015\/257932","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}