{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T07:23:14Z","timestamp":1649056994453},"reference-count":10,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Hematology"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p><jats:italic>Objective and Importance<\/jats:italic>. Invasive mucormycosis may complicate the course of patients with hematologic malignancies and has a very high mortality rate. Early diagnosis and aggressive approach combined with surgical and medical treatment have paramount importance for cure.<jats:italic>Clinical Presentation<\/jats:italic>. We report here a case of a patient with acute lymphoblastic leukemia presenting with a subcutaneous mass lesion which was sampled by an ultrasound guided needle biopsy. The pathology showed microorganisms with aseptate hyphae with wide, irregular walls and more or less branching with highly vertical angles which suggested a mold infection. The specimen was also cultured where<jats:italic>Rhizopus<\/jats:italic>spp. grew.<jats:italic>Conclusion<\/jats:italic>. Posaconazole 200\u2009mg QID was commenced. She recovered from neutropenia and pain on day 20 of treatment. After 4 courses of hyper-CVAD chemotherapy, the remaining soft tissue mass was removed surgically and she underwent allogeneic HSCT from a full matched sibling donor under secondary prophylaxis.<\/jats:p>","DOI":"10.1155\/2015\/285360","type":"journal-article","created":{"date-parts":[[2015,2,15]],"date-time":"2015-02-15T21:02:34Z","timestamp":1424034154000},"page":"1-4","source":"Crossref","is-referenced-by-count":0,"title":["A Proven Case of Cutaneous<i>Rhizopus<\/i>Infection Presenting with Severe Limb Pain Very Soon after Induction Treatment in a Patient with Acute Lymphoblastic Leukemia"],"prefix":"10.1155","volume":"2015","author":[{"given":"Mehmet Sezgin","family":"Pepeler","sequence":"first","affiliation":[{"name":"Department of Hematology, Gazi University Faculty of Medicine, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kadir","family":"Acar","sequence":"additional","affiliation":[{"name":"Department of Hematology, Gazi University Faculty of Medicine, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6zlem","family":"G\u00fczel Tun\u00e7can","sequence":"additional","affiliation":[{"name":"Department of Infectious Disease, Gazi University Faculty of Medicine, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"\u00d6mer","family":"Uluo\u011flu","sequence":"additional","affiliation":[{"name":"Department of Pathology, Gazi University Faculty of Medicine, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ay\u015fe","family":"Kalkanc\u0131","sequence":"additional","affiliation":[{"name":"Department of Microbiology, Gazi University Faculty of Medicine, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hakan","family":"Atalar","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Gazi University Faculty of Medicine, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Koray","family":"K\u0131l\u0131\u00e7","sequence":"additional","affiliation":[{"name":"Department of Radiology, Gazi University Faculty of Medicine, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G\u00fclsan","family":"T\u00fcrk\u00f6z Sucak","sequence":"additional","affiliation":[{"name":"Department of Hematology, Gazi University Faculty of Medicine, Ankara, Turkey"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-006-0107-1"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1086\/432579"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1186\/1752-1947-7-263"},{"issue":"6","key":"4","first-page":"62","volume":"90","year":"2005","journal-title":"Haematologica"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1128\/aac.47.11.3647-3650.2003"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1086\/375075"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.3109\/08880018.2013.770587"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2009.04.007"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1086\/500212"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1080\/13693780801975576"}],"container-title":["Case Reports in Hematology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2015\/285360.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2015\/285360.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crihem\/2015\/285360.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T17:16:54Z","timestamp":1471540614000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crihem\/2015\/285360\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":10,"alternative-id":["285360","285360"],"URL":"https:\/\/doi.org\/10.1155\/2015\/285360","relation":{},"ISSN":["2090-6560","2090-6579"],"issn-type":[{"value":"2090-6560","type":"print"},{"value":"2090-6579","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}