{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,8]],"date-time":"2025-10-08T15:05:50Z","timestamp":1759935950427,"version":"3.37.3"},"reference-count":27,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31272515","31472165"],"award-info":[{"award-number":["31272515","31472165"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["31272515","31472165"],"award-info":[{"award-number":["31272515","31472165"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>This study involved a death which occurred in four Himalayan griffons housed in Beijing zoo, China. Based on pathogen identification and the pathological changes observed, we did characterize the fungi and Hepatitis E virus (HEV) in four dead Himalayan griffons. Pathological changes were severe. Membranous-like material was observed on the surface of the internal organs. Spleen was necrotic. Focal lymphocyte infiltration in the liver and many sunflower-like fungi nodules were evident in the tissues, especially in the kidney. PCR was used to identify the pathogen. Based on the 18SrRNA genomic sequence of known fungi, the results confirmed that all four dead Himalayan griffons were infected with<jats:italic>Aspergillus<\/jats:italic>. At the same time the detection of HEV also showed positive results. To the best of our knowledge, this work appears to be the first report of concurrent presence of Aspergillosis and Hepatitis E virus in rare avian species.<\/jats:p>","DOI":"10.1155\/2015\/287315","type":"journal-article","created":{"date-parts":[[2015,10,28]],"date-time":"2015-10-28T22:59:18Z","timestamp":1446073158000},"page":"1-9","source":"Crossref","is-referenced-by-count":14,"title":["Case Report Associated with Aspergillosis and Hepatitis E Virus Coinfection in Himalayan Griffons"],"prefix":"10.1155","volume":"2015","author":[{"given":"Heng","family":"Li","sequence":"first","affiliation":[{"name":"Laboratory of Veterinary Pathology and Public Health, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rining","family":"Zhu","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Pathology and Public Health, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruiping","family":"She","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Pathology and Public Health, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Chenglin","family":"Zhang","sequence":"additional","affiliation":[{"name":"Beijing Zoo, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ruihan","family":"Shi","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Pathology and Public Health, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wei","family":"Li","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Pathology and Public Health, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fang","family":"Du","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Pathology and Public Health, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Qiaoxing","family":"Wu","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Pathology and Public Health, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fengjiao","family":"Hu","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Pathology and Public Health, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yang","family":"Zhang","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Pathology and Public Health, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Majid Hussain","family":"Soomro","sequence":"additional","affiliation":[{"name":"Laboratory of Veterinary Pathology and Public Health, College of Veterinary Medicine, China Agricultural University, Beijing 100193, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Changming","family":"Zheng","sequence":"additional","affiliation":[{"name":"Beijing Zoo, Beijing, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2148-6-65"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1579\/0044-7447-38.3.166"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1080\/13693780400020089"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1080\/03079457.2010.506210"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1637\/8283-031208-case.1"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/s11046-014-9833-6"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1637\/9232-011110-case.1"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1556\/avet.52.2004.1.8"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.2307\/1588433"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1080\/03079459208418830"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.virusres.2007.02.002"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1186\/1743-422x-10-341"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1007\/s10096-012-1740-5"},{"issue":"10","key":"14","doi-asserted-by":"crossref","first-page":"2601","DOI":"10.1128\/JCM.33.10.2601-2606.1995","volume":"33","year":"1995","journal-title":"Journal of Clinical Microbiology"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1006\/mcpr.2000.0324"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.94.18.9860"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1016\/0042-6822(91)90760-9"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.19582-0"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1007\/s007050170002"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.42.1.329-338.2004"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.05388-11"},{"issue":"2","key":"22","first-page":"228","volume":"75","year":"2006","journal-title":"Mikrobiologiia"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.3184\/175815513x13818257354160"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.21536"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(03)14025-1"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1016\/j.hepres.2005.10.010"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1056\/nejmra1204512"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/287315.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/287315.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/287315.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,10]],"date-time":"2020-09-10T13:56:26Z","timestamp":1599746186000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.hindawi.com\/journals\/bmri\/2015\/287315\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":27,"alternative-id":["287315","287315"],"URL":"https:\/\/doi.org\/10.1155\/2015\/287315","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"type":"print","value":"2314-6133"},{"type":"electronic","value":"2314-6141"}],"subject":[],"published":{"date-parts":[[2015]]}}}