{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2022,4,4]],"date-time":"2022-04-04T20:05:18Z","timestamp":1649102718523},"reference-count":17,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Oncological Medicine"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p><jats:italic>Introduction<\/jats:italic>. Aggressive angiomyxoma is a rare, slowly growing, and benign tumour of mesenchymal origin, which affects women of reproductive age and is associated with a high risk of local recurrence.<jats:italic>Case Presentation<\/jats:italic>. A case of a 47-year-old white female is presented herein, with a large polypoid, gelatinous mass on the right labia majora, measuring 26 \u00d7 21 \u00d7 6\u2009cm. Histopathologically, the lesion was composed of spindle and stellate-shaped cells embedded in a myxoid matrix. Another specific feature was the presence of variable-sized thin-walled capillaries and thick-walled vascular channels. The patient underwent wide local excision of the tumour with clear margins and developed local recurrence 18 months later.<jats:italic>Discussion<\/jats:italic>. Aggressive angiomyxoma of the vulva needs to be distinguished from benign myxoid tumors with a low risk of local recurrence as well as from malignant myxoid neoplasms. Usually wide local excision with tumour-free margins and occasionally hormonal manipulation is the treatment of choice.<\/jats:p>","DOI":"10.1155\/2015\/292304","type":"journal-article","created":{"date-parts":[[2015,4,22]],"date-time":"2015-04-22T21:02:27Z","timestamp":1429736547000},"page":"1-4","source":"Crossref","is-referenced-by-count":1,"title":["Aggressive Angiomyxoma of the Vulva: A Bizarre Perineal Lesion"],"prefix":"10.1155","volume":"2015","author":[{"given":"Adamantia","family":"Zizi-Sermpetzoglou","sequence":"first","affiliation":[{"name":"Pathology Department, \u201cTzaneion\u201d General Hospital, 185 36 Piraeus, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Despoina","family":"Myoteri","sequence":"additional","affiliation":[{"name":"Pathology Department, \u201cTzaneion\u201d General Hospital, 185 36 Piraeus, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kalliroi","family":"Koulia","sequence":"additional","affiliation":[{"name":"Pathology Department, \u201cTzaneion\u201d General Hospital, 185 36 Piraeus, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vassilios","family":"Kontostolis","sequence":"additional","affiliation":[{"name":"2nd Department of Surgery, \u201cTzaneion\u201d General Hospital, 185 36 Piraeus, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hippokratis","family":"Moschouris","sequence":"additional","affiliation":[{"name":"Radiology & Interventional Radiology Department, \u201cTzaneion\u201d General Hospital, 185 36 Piraeus, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dionysios","family":"Dellaportas","sequence":"additional","affiliation":[{"name":"2nd Department of Surgery, University Hospital \u201cAretaeion\u201d, 115 28 Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-198307000-00009"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.7860\/jcdr\/2014\/8446.4315"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1007\/s00404-010-1575-1"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1001\/archderm.1986.01660190068018"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.3348\/kjr.2012.13.1.90"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinimag.2014.04.001"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.13.11668"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-004-1135-9"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1007\/s00428-006-0186-5"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1002\/gcc.1179"},{"issue":"2","key":"11","first-page":"164","volume":"72","year":"2014","journal-title":"Obstetrics & Gynecology Science"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.issn.0376-2491.2012.22.013"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/j.ygyno.2005.09.033"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.07.2120"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1097\/LGT.0b013e3182545d2f"},{"issue":"1","key":"16","first-page":"68","volume":"82","year":"2011","journal-title":"Ginekologia Polska"},{"issue":"3","key":"17","first-page":"345","volume":"64","year":"2014","journal-title":"Journal of the Pakistan Medical Association"}],"container-title":["Case Reports in Oncological Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crionm\/2015\/292304.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crionm\/2015\/292304.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crionm\/2015\/292304.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T16:57:47Z","timestamp":1471539467000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crionm\/2015\/292304\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":17,"alternative-id":["292304","292304"],"URL":"https:\/\/doi.org\/10.1155\/2015\/292304","relation":{},"ISSN":["2090-6706","2090-6714"],"issn-type":[{"value":"2090-6706","type":"print"},{"value":"2090-6714","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}