{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,29]],"date-time":"2026-04-29T04:31:42Z","timestamp":1777437102285,"version":"3.51.4"},"reference-count":25,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Macrophage activation syndrome (MAS) is a potentially fatal condition. It belongs to the hemophagocytic lymphohistiocytosis group of diseases. In adults, MAS is rarely associated with systemic lupus erythematosus, but it also arises as complication of several systemic autoimmune disorders, like ankylosing spondylitis, rheumatoid arthritis, and adult-onset Still\u2019s disease. Several treatment options for MAS have been reported in the literature, including a therapeutic regimen of etoposide, dexamethasone, and cyclosporine. Here we report a case of 42-year-old woman in whom MAS occurred as onset of systemic lupus erythematosus.<\/jats:p>","DOI":"10.1155\/2015\/294041","type":"journal-article","created":{"date-parts":[[2015,5,7]],"date-time":"2015-05-07T21:22:05Z","timestamp":1431033725000},"page":"1-4","source":"Crossref","is-referenced-by-count":30,"title":["Macrophage Activation Syndrome as Onset of Systemic Lupus Erythematosus: A Case Report and a Review of the Literature"],"prefix":"10.1155","volume":"2015","author":[{"given":"Guido","family":"Granata","sequence":"first","affiliation":[{"name":"UOC Immunologia Clinica A, Dipartimento di Medicina Clinica, Policlinico Umberto I, Sapienza Universit\u00e0 di Roma, 00185 Roma, Italy"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dario","family":"Didona","sequence":"additional","affiliation":[{"name":"I Divisione Dermatologica, Istituto Dermopatico dell\u2019Immacolata IRCCS, 00167 Roma, 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