{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T12:06:51Z","timestamp":1773922011761,"version":"3.50.1"},"reference-count":24,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Cardiology"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Pericardial effusion is a common cardiac manifestation of hypothyroidism, but effusion resulting in cardiac tamponade is extremely rare. We present a case of a 56-year-old African American woman with slurred speech and altered mental status that was initially suspected to have stroke. Her chest X-ray revealed cardiomegaly and subsequent echocardiogram showed a large pericardial effusion with echocardiographic evidence of cardiac tamponade. Clinically, patient did not have pulsus paradoxus or hypotension. Further questioning revealed a history of total surgical thyroidectomy and noncompliance with thyroid replacement therapy. Pericardiocentesis was performed promptly and thyroxine replacement therapy was started. Thereafter, her mental status improved significantly. The management of pericardial effusion associated with hypothyroidism varies depending on size of effusion and hemodynamic stability of the patient. The management strategy ranges from conservative management with close monitoring and thyroxine replacement to pericardiocentesis or creation of a pericardial window.<\/jats:p>","DOI":"10.1155\/2015\/310350","type":"journal-article","created":{"date-parts":[[2015,7,30]],"date-time":"2015-07-30T17:30:08Z","timestamp":1438277408000},"page":"1-5","source":"Crossref","is-referenced-by-count":5,"title":["Early Cardiac Tamponade in a Patient with Postsurgical Hypothyroidism"],"prefix":"10.1155","volume":"2015","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9404-1679","authenticated-orcid":true,"given":"Archana","family":"Sinha","sequence":"first","affiliation":[{"name":"Division of Cardiology, Saint Luke\u2019s University Health Network, Bethlehem, PA 18015, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sri Lakshmi Hyndavi","family":"Yeruva","sequence":"additional","affiliation":[{"name":"Division of Hematology and Oncology, Howard University Hospital, 2041 Georgia Avenue NW, Washington, DC 20060, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rajan","family":"Kumar","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Saint Luke\u2019s University Health Network, Bethlehem, PA 18015, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bryan H.","family":"Curry","sequence":"additional","affiliation":[{"name":"Division of Cardiology, Howard University Hospital, 2041 Georgia Avenue NW, Washington, DC 20060, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijcard.2009.03.090"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-12-2011-5281"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1136\/bcr.04.2011.4117"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1136\/pgmj.58.682.473"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1161\/circulationaha.106.678326"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.4236\/wjcd.2012.24051"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2013.10.093"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1136\/bcr-2014-204076"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1055\/s-0031-1284201"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2013.11.038"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1016\/j.jccase.2013.03.011"},{"issue":"6","key":"12","first-page":"580","volume":"78","year":"2002","journal-title":"Arquivos Brasileiros de Cardiologia"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1016\/0002-8703(90)90253-t"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajem.2009.04.024"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1097\/maj.0b013e3181e664c6"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2012.05.042"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.5543\/tkda.2012.42078"},{"issue":"5","key":"18","doi-asserted-by":"crossref","first-page":"H2061","DOI":"10.1152\/ajpheart.2001.280.5.H2061","volume":"280","year":"2001","journal-title":"The American Journal of Physiology\u2014Heart and Circulatory Physiology"},{"issue":"1","key":"19","doi-asserted-by":"crossref","first-page":"81","DOI":"10.1080\/08998280.2007.11928243","volume":"20","year":"2007","journal-title":"Proceedings (Baylor University. 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