{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,4]],"date-time":"2026-04-04T11:31:24Z","timestamp":1775302284686,"version":"3.50.1"},"reference-count":28,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Surgery Research and Practice"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. The role of early laparoscopic cholecystectomy for acute cholecystitis with cholelithiasis is not yet established. The aim of our prospective randomized study was to evaluate the safety and feasibility of early LC for acute cholecystitis and to compare the results with delayed LC.<jats:italic>Methods<\/jats:italic>. Between March 2007 to December 2008, 50 patients with diagnosis of acute cholecystitis were assigned randomly to early group,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>25<\/mml:mn><\/mml:math>(LC within 24\u2009hrs of admission), and delayed group,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>25<\/mml:mn><\/mml:math>(initial conservative treatment followed by delayed LC, 6\u20138 weeks later).<jats:italic>Results<\/jats:italic>. We found in our study that the conversion rate in early LC and delayed LC was 16% and 8%, respectively, Operation time for early LC was 69.4\u2009min versus 66.4\u2009min for delayed LC, postoperative complications for early LC were 24% versus 8% for delayed LC, and blood loss was 159.6\u2009mL early group versus 146.8\u2009mL for delayed group. However early LC had significantly shorter hospital stay (4.1 days versus 8.6 days).<jats:italic>Conclusions<\/jats:italic>. Early LC for acute cholecystitis with cholelithiasis is safe and feasible, offering the additional benefit of shorter hospital stay. It should be offered to the patients with acute cholecystitis, provided that the surgery is performed within 96\u2009hrs of acute symptoms by an experienced surgeon.<\/jats:p>","DOI":"10.1155\/2015\/349801","type":"journal-article","created":{"date-parts":[[2015,2,3]],"date-time":"2015-02-03T16:00:43Z","timestamp":1422979243000},"page":"1-7","source":"Crossref","is-referenced-by-count":18,"title":["Evaluation of Early versus Delayed Laparoscopic Cholecystectomy in Acute Cholecystitis"],"prefix":"10.1155","volume":"2015","author":[{"given":"Rati","family":"Agrawal","sequence":"first","affiliation":[{"name":"DNB (General Surgery), Department of General Surgery, Maharaja Agrasen Hospital (MAH), New Delhi 110026, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K. C.","family":"Sood","sequence":"additional","affiliation":[{"name":"DNB (General Surgery), Department of General Surgery, Maharaja Agrasen Hospital (MAH), New Delhi 110026, India"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Bhupender","family":"Agarwal","sequence":"additional","affiliation":[{"name":"DNB (General Surgery), Department of General Surgery, Maharaja Agrasen Hospital (MAH), New Delhi 110026, India"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjsurg.2007.03.004"},{"issue":"1","key":"2","first-page":"65","volume":"6","year":"2002","journal-title":"JSLS: Journal of the Society of Laparoendoscopic Surgeons\/Society of Laparoendoscopic Surgeons"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199601000-00006"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199804000-00001"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/s1091-255x(03)00065-9"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-003-9230-6"},{"key":"7","first-page":"847","volume-title":"Cholecystectomy (open and laproscopy)","year":"2007"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1097\/00129689-200304000-00002"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800681102"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1016\/0002-9610(91)90603-B"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.1800811130"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.305.6850.394"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1097\/00000658-199106000-00017"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.1996.01430170086016"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1055\/s-2007-1010349"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(97)08447-x"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2168.1998.00708.x"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9610(02)00789-4"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1002\/bjs.4831"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1097\/01.sle.0000153730.24862.0a"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1007\/s00595-005-2998-3"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1007\/s00464-005-0100-2"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1046\/j.1572-0241.2003.04002.x"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1001\/archsurg.143.6.533"},{"issue":"89","key":"25","first-page":"11","volume":"56","year":"2009","journal-title":"Hepato-Gastroenterology"},{"issue":"89","key":"26","first-page":"26","volume":"56","year":"2009","journal-title":"Hepatogastroenterology"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1007\/s002689900008"},{"issue":"2","key":"28","first-page":"115","volume":"11","year":"2002","journal-title":"Romanian Journal of Gastroenterology"}],"container-title":["Surgery Research and Practice"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/srp\/2015\/349801.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/srp\/2015\/349801.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/srp\/2015\/349801.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,7,27]],"date-time":"2016-07-27T09:27:58Z","timestamp":1469611678000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/srp\/2015\/349801\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":28,"alternative-id":["349801","349801"],"URL":"https:\/\/doi.org\/10.1155\/2015\/349801","relation":{},"ISSN":["2356-7759","2356-6124"],"issn-type":[{"value":"2356-7759","type":"print"},{"value":"2356-6124","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}