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Three patients had pathologically established nasopharyngeal malignancy. In the 3 nasopharyngeal malignancies, 2 had diffusely and expansively increased FDG uptake, and one had asymmetric uptake. Our results indicated that the difference between adenoid hypertrophy and malignancy is asymmetric or diffusely expansive<jats:sup>18<\/jats:sup>F-FDG uptake with or without correlating morphologic lesion on diagnostic CT in children under 10 years of age. The typical characteristics of physiologic and inflammatory<jats:sup>18<\/jats:sup>F-FDG uptake in nasopharynx are symmetrically trapezoid. Diffusely increased nasopharyngeal FDG uptake can be considered physiologic if<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:msub><mml:mrow><mml:mtext>SUV<\/mml:mtext><\/mml:mrow><mml:mrow><mml:mtext>max<\/mml:mtext><\/mml:mrow><\/mml:msub><\/mml:mrow><\/mml:math>is less than 7.6 but should be carefully assessed by pharyngorhinoscopy if<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:msub><mml:mrow><mml:mtext>SUV<\/mml:mtext><\/mml:mrow><mml:mrow><mml:mtext>max<\/mml:mtext><\/mml:mrow><\/mml:msub><\/mml:mrow><\/mml:math>is greater than 11 and there is no correlating morphologic lesion on diagnostic CT. The diffusely, expansively increased uptake, and asymmetric uptake in particular, should be considered as malignancy. Further biopsy is especially indicated in patients with retropharyngeal space and bilateral cervical lymph node abnormality but no history of malignancy.<\/jats:p>","DOI":"10.1155\/2015\/354970","type":"journal-article","created":{"date-parts":[[2015,10,20]],"date-time":"2015-10-20T17:06:30Z","timestamp":1445360790000},"page":"1-5","source":"Crossref","is-referenced-by-count":1,"title":["<sup>18<\/sup>F-FDG Uptake Characteristics in Differentiating Benign from Malignant Nasopharyngeal Lesions in Children"],"prefix":"10.1155","volume":"2015","author":[{"given":"Chao","family":"Ma","sequence":"first","affiliation":[{"name":"Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renjian","family":"Zou","sequence":"additional","affiliation":[{"name":"Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanlei","family":"Huo","sequence":"additional","affiliation":[{"name":"Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suyun","family":"Chen","sequence":"additional","affiliation":[{"name":"Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaoyan","family":"Wang","sequence":"additional","affiliation":[{"name":"Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shuqi","family":"Wu","sequence":"additional","affiliation":[{"name":"Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhiyi","family":"Ye","sequence":"additional","affiliation":[{"name":"Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Zhenyu","family":"Wu","sequence":"additional","affiliation":[{"name":"Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Feng","family":"Fang","sequence":"additional","affiliation":[{"name":"Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hui","family":"Wang","sequence":"additional","affiliation":[{"name":"Nuclear Medicine, Xinhua Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai 200092, China"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"year":"1999","key":"1"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1007\/s00259-012-2091-2"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.oraloncology.2013.05.005"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.2214\/AJR.13.12420"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/j.1754-9485.2011.02252.x"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijrobp.2006.12.028"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1007\/s00247-010-1844-y"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/s1470-2045(03)00956-2"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/354970.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/354970.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/354970.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,7,27]],"date-time":"2016-07-27T07:55:54Z","timestamp":1469606154000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/bmri\/2015\/354970\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":8,"alternative-id":["354970","354970"],"URL":"https:\/\/doi.org\/10.1155\/2015\/354970","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"type":"print","value":"2314-6133"},{"type":"electronic","value":"2314-6141"}],"subject":[],"published":{"date-parts":[[2015]]}}}