{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T04:14:20Z","timestamp":1784693660468,"version":"3.55.0"},"reference-count":12,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Ceruminous adenomas are benign tumors that are rare in humans and present with a nonspecific symptomatology. The treatment of choice is surgical excision. We present an 87-year-old woman who presented with a reddish, tender, round, soft mass of the outer third of the inferior wall of the left external auditory canal, discharging a yellowish fluid upon pressure. Coincidentally, due to her poor general condition, this patient also showed symptoms consistent with chronic otitis media, parotitis, and cervical lymphadenopathy, such as otorrhea, through a ruptured tympanic membrane and swelling of the parotid gland and cervical lymph nodes. The external auditory canal lesion was surgically excised under general anesthesia, utilizing a transmeatal approach. The pathological diagnosis was ceruminous gland adenoma. The tumor was made of tubular and cystic structures and embedded in a fibrous, focally hyalinized stroma. Immunohistochemistry confirmed the presence of two distinct cell populations. The luminal cells expressed keratin 7, while peripheral (basal) cells expressed keratins 5\/6, S100 protein, and p63. The apocrine gland-related antigen GCDFP-15 was focally expressed by tumor cells. The postoperative course was uneventful and at the 2-year follow-up no recurrence of the ceruminous adenoma was noted.<\/jats:p>","DOI":"10.1155\/2015\/359627","type":"journal-article","created":{"date-parts":[[2015,11,16]],"date-time":"2015-11-16T21:01:30Z","timestamp":1447707690000},"page":"1-3","source":"Crossref","is-referenced-by-count":7,"title":["Ceruminous Adenoma of the External Auditory Canal: A Case Report with Imaging and Pathologic Findings"],"prefix":"10.1155","volume":"2015","author":[{"given":"George","family":"Psillas","sequence":"first","affiliation":[{"name":"1st Academic ENT Department, Aristotle University of Thessaloniki, AHEPA Hospital, 1 Stilponos Kyriakidi Street, 546 36 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Argyrios","family":"Krommydas","sequence":"additional","affiliation":[{"name":"1st Academic ENT Department, Aristotle University of Thessaloniki, AHEPA Hospital, 1 Stilponos Kyriakidi Street, 546 36 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgia","family":"Karayannopoulou","sequence":"additional","affiliation":[{"name":"Department of Pathology, Aristotle University of Thessaloniki, School of Medicine, 541 24 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyriakos","family":"Chatzopoulos","sequence":"additional","affiliation":[{"name":"Department of Pathology, Aristotle University of Thessaloniki, School of Medicine, 541 24 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"Kanitakis","sequence":"additional","affiliation":[{"name":"Department of Dermatology, Ed. Herriot Hospital Group, Lyon, France"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Konstantinos","family":"Markou","sequence":"additional","affiliation":[{"name":"1st Academic ENT Department, Aristotle University of Thessaloniki, AHEPA Hospital, 1 Stilponos Kyriakidi Street, 546 36 Thessaloniki, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"98","reference":[{"issue":"3","key":"5","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1017\/S0022215100129652","volume":"109","year":"1995","journal-title":"The Journal of Laryngology and Otology"},{"key":"1","doi-asserted-by":"publisher","DOI":"10.1097\/00000478-200403000-00003"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1001\/archotol.1967.00760050068014"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/s0385-8146(03)00055-5"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(197205)29:560;1169::aid-cncr282029050762;3.0.co;2-8"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1054\/bjps.1997.0075"},{"issue":"4","key":"7","doi-asserted-by":"crossref","first-page":"870","DOI":"10.1002\/1097-0142(19890815)64:4<870::AID-CNCR2820640418>3.0.CO;2-3","volume":"64","year":"1989","journal-title":"Cancer"},{"issue":"5","key":"8","first-page":"449","volume":"32","year":"1996","journal-title":"Journal of the American Animal Hospital Association"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1097\/mao.0b013e3181db7545"},{"issue":"1","key":"10","doi-asserted-by":"crossref","first-page":"34","DOI":"10.1177\/014107689008300115","volume":"83","year":"1990","journal-title":"Journal of the Royal Society of Medicine"},{"issue":"4","key":"11","first-page":"195","volume":"3","year":"2007","journal-title":"B-ENT"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1007\/s00405-006-0166-z"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2015\/359627.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2015\/359627.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2015\/359627.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,9,1]],"date-time":"2019-09-01T15:52:51Z","timestamp":1567353171000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crim\/2015\/359627\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":12,"alternative-id":["359627","359627"],"URL":"https:\/\/doi.org\/10.1155\/2015\/359627","relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"value":"1687-9627","type":"print"},{"value":"1687-9635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}