{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,27]],"date-time":"2026-04-27T12:52:30Z","timestamp":1777294350030,"version":"3.51.4"},"reference-count":27,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/100007405","name":"The Danish Heart Foundation","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100007405","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100006308","name":"Helga og Peter Kornings Fond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100006308","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004331","name":"Snedkermester Sophus Jacobsen og Hustru Astrid Jacobsens Fond","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100004331","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Ydes Foundation"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p><jats:italic>Objective.<\/jats:italic>To compare the quantity, subtype, and progression of atherosclerosis by cardiac computed tomography (CT) and intravascular ultrasound (IVUS) in patients with stable (SAP) and unstable angina pectoris or non-ST-elevation myocardial infarction (UAP\/n-STEMI).<jats:italic>Methods.<\/jats:italic>Forty patients with SAP and 20 with UAP\/n-STEMI underwent cardiac CT and angiography with IVUS at baseline and after one year. Atherosclerotic segments were divided into calcified, mixed, or noncalcified subtypes, and significant stenoses were registered.<jats:italic>Results.<\/jats:italic>Thirty-two SAP and 15 UAP\/n-STEMI patients completed the CT follow-up. At baseline, the number of atherosclerotic segments was higher in UAP\/n-STEMI than in SAP (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.039<\/mml:mn><\/mml:math>). UAP\/n-STEMI patients had more segments with noncalcified plaques (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.0005<\/mml:mn><\/mml:math>) whereas SAP patients had more segments with calcified plaques (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.013<\/mml:mn><\/mml:math>). The number of segments with significant stenosis did not differ between the groups, but noncalcified plaques more frequently caused significant stenoses in UAP\/n-STEMI than in SAP patients (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.0002<\/mml:mn><\/mml:math>). After one year the number of segments with atherosclerosis increased in SAP patients (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.0001<\/mml:mn><\/mml:math>). The number of atherosclerotic segments remained unchanged in UAP\/n-STEMI patients. However, composition was altered as the number of segments with noncalcified plaques decreased (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.018<\/mml:mn><\/mml:math>). IVUS data confirmed the CT findings.<jats:italic>Conclusion.<\/jats:italic>Quantity, subtype, and progression of atherosclerosis differ between SAP and UAP\/n-STEMI patients.<\/jats:p>","DOI":"10.1155\/2015\/401357","type":"journal-article","created":{"date-parts":[[2015,8,4]],"date-time":"2015-08-04T02:28:11Z","timestamp":1438655291000},"page":"1-9","source":"Crossref","is-referenced-by-count":17,"title":["Different Plaque Composition and Progression in Patients with Stable and Unstable Coronary Syndromes Evaluated by Cardiac CT"],"prefix":"10.1155","volume":"2015","author":[{"given":"Maiken Glud","family":"Dalager","sequence":"first","affiliation":[{"name":"Department of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Morten","family":"B\u00f8ttcher","sequence":"additional","affiliation":[{"name":"Cardiac Imaging Center, Hospital Unit Vest, Gl. Landevej 61, 7400 Herning, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesper","family":"Thygesen","sequence":"additional","affiliation":[{"name":"Department of Biomedical Engineering, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gratien","family":"Andersen","sequence":"additional","affiliation":[{"name":"Department of Radiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans Erik","family":"B\u00f8tker","sequence":"additional","affiliation":[{"name":"Department of Cardiology, Aarhus University Hospital, Palle Juul-Jensens Boulevard 99, 8200 Aarhus N, Denmark"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1161\/01.atv.20.5.1262"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-8703(99)70267-x"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.01.041"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1080\/17482940601052648"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/s0002-9149(02)03411-2"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehn356"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1253\/circj.68.840"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.0000087481.55887.c9"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2005.09.068"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.3.657"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1097\/00004728-200407000-00003"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcct.2010.05.016"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1007\/s10554-010-9695-z"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.07.070"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2012.10.028"},{"key":"16","first-page":"2949","volume":"43","year":"2013","journal-title":"European Heart Journal"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1093\/eurheartj\/ehr236"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1161\/01.cir.51.4.5"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.amjcard.2011.01.024"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa1002358"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1001\/jama.291.9.1071"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1001\/jama.295.13.jpc60002"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1097\/01.rli.0000254408.96355.85"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/j.jacc.2006.12.014"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcct.2009.10.012"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.2214\/ajr.07.2763"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcct.2008.12.005"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/401357.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/401357.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/401357.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2016,8,18]],"date-time":"2016-08-18T14:00:19Z","timestamp":1471528819000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/bmri\/2015\/401357\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":27,"alternative-id":["401357","401357"],"URL":"https:\/\/doi.org\/10.1155\/2015\/401357","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}