{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T20:27:20Z","timestamp":1790713640048,"version":"4.1.0"},"reference-count":25,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81400385"],"award-info":[{"award-number":["81400385"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2012B010300010"],"award-info":[{"award-number":["2012B010300010"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2014QN10"],"award-info":[{"award-number":["2014QN10"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"name":"Guangdong Scientific Program 2012 in China","award":["81400385"],"award-info":[{"award-number":["81400385"]}]},{"name":"Guangdong Scientific Program 2012 in China","award":["2012B010300010"],"award-info":[{"award-number":["2012B010300010"]}]},{"name":"Guangdong Scientific Program 2012 in China","award":["2014QN10"],"award-info":[{"award-number":["2014QN10"]}]},{"name":"Fundamental Research Funds of the State Key Laboratory of Ophthalmology","award":["81400385"],"award-info":[{"award-number":["81400385"]}]},{"name":"Fundamental Research Funds of the State Key Laboratory of Ophthalmology","award":["2012B010300010"],"award-info":[{"award-number":["2012B010300010"]}]},{"name":"Fundamental Research Funds of the State Key Laboratory of Ophthalmology","award":["2014QN10"],"award-info":[{"award-number":["2014QN10"]}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Ophthalmology"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p><jats:italic>Objective<\/jats:italic>. To compare fourier-domain optical coherence tomography (FD-OCT) and time-domain OCT (TD-OCT) in the determination of thinnest corneal thickness (TCT).<jats:italic>Methods<\/jats:italic>. This study included 55 keratoconus patients and 50 healthy volunteers. The RTVue-OCT (FD-OCT) and Visante-OCT (TD-OCT) were used for the measurement of the TCT. Three consecutive scans were performed. The comparison and agreement between the two modalities were analyzed by paired<jats:italic>t<\/jats:italic>-test, the Pearson correlation, intraclass correlation coefficient (ICC), and Bland-Altman plots. intraobserver repeatability was analyzed by the intraobserver within-subject standard deviation (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mrow><mml:msub><mml:mrow><mml:mi>S<\/mml:mi><\/mml:mrow><mml:mrow><mml:mo stretchy=\"false\">(<\/mml:mo><mml:mi>w<\/mml:mi><mml:mo stretchy=\"false\">)<\/mml:mo><\/mml:mrow><\/mml:msub><\/mml:mrow><\/mml:math>), coefficient of variation (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mrow><mml:msub><mml:mrow><mml:mtext>CV<\/mml:mtext><\/mml:mrow><mml:mrow><mml:mo stretchy=\"false\">(<\/mml:mo><mml:mi>w<\/mml:mi><mml:mo stretchy=\"false\">)<\/mml:mo><\/mml:mrow><\/mml:msub><\/mml:mrow><\/mml:math>), and ICC.<jats:italic>Results<\/jats:italic>. The TCT value of normal corneas was higher by RTVue-OCT (530.4 \u00b1 19.7\u2009<jats:italic>\u03bc<\/jats:italic>m) than Visante-OCT (521.5 \u00b1 18.3\u2009<jats:italic>\u03bc<\/jats:italic>m) (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:math>). For keratoconus eyes, the TCT was 425.0 \u00b1 58.2\u2009<jats:italic>\u03bc<\/jats:italic>m and 424.4 \u00b1 55.7\u2009<jats:italic>\u03bc<\/jats:italic>m (difference being 0.6 \u00b1 10.2\u2009<jats:italic>\u03bc<\/jats:italic>m,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mi>p<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.604<\/mml:mn><\/mml:math>). Strong correlation (<jats:italic>r<\/jats:italic>= 0.938\u223c0.985) (ICC = 0.915\u20130.984) was observed between the two OCTs, and each OCT exhibited excellent repeatability in determining the TCT in all subjects (ICC = 0.984\u20130.994).<jats:italic>Conclusions<\/jats:italic>. The values of TCT obtained from RTVue-OCT and Visante-OCT were highly correlated; however, the two values were different. Both OCT instruments exhibited good intraobserver reliability. The existence of systematic differences suggested that the two instruments cannot be used interchangeably.<\/jats:p>","DOI":"10.1155\/2015\/402925","type":"journal-article","created":{"date-parts":[[2015,6,25]],"date-time":"2015-06-25T20:07:01Z","timestamp":1435262821000},"page":"1-7","source":"Crossref","is-referenced-by-count":11,"title":["Comparison of Fourier-Domain and Time-Domain Optical Coherence Tomography in the Measurement of Thinnest Corneal Thickness in Keratoconus"],"prefix":"10.1155","volume":"2015","author":[{"given":"Chunxiao","family":"Wang","sequence":"first","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong 510060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueying","family":"Xia","sequence":"additional","affiliation":[{"name":"Guangdong Women and Children Hospital, Guangzhou, Guangdong 510000, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bishan","family":"Tian","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong 510060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shiyou","family":"Zhou","sequence":"additional","affiliation":[{"name":"State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, Guangdong 510060, China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/0039-6257(84)90094-8"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2008.08.004"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1016\/S0886-3350(02)01495-5"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3180334f78"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1016\/j.clae.2008.07.006"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e3181861c29"},{"key":"7","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2006.01.048"},{"key":"8","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2006.10.033"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1016\/s0886-3350(01)01162-2"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2008.01823.x"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.125.8.1027"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1001\/archopht.123.12.1715"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1364\/ol.28.002067"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1097\/ICO.0b013e318261eb2b"},{"issue":"6","key":"15","doi-asserted-by":"crossref","first-page":"539","DOI":"10.3928\/1081-597X-20060601-05","volume":"22","year":"2006","journal-title":"Journal of Refractive Surgery"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2008.12.032"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.07-1326"},{"key":"18","doi-asserted-by":"publisher","DOI":"10.1136\/bjophthalmol-2012-302648"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2009.03.012"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1007\/s00417-010-1360-7"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2007.07.006"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1111\/j.1442-9071.2004.00805.x"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/j.ophtha.2013.05.027"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2005.06.026"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.11-9033"}],"container-title":["Journal of Ophthalmology"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2015\/402925.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2015\/402925.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/joph\/2015\/402925.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,27]],"date-time":"2019-08-27T14:39:30Z","timestamp":1566916770000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/joph\/2015\/402925\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":25,"alternative-id":["402925","402925"],"URL":"https:\/\/doi.org\/10.1155\/2015\/402925","relation":{},"ISSN":["2090-004X","2090-0058"],"issn-type":[{"value":"2090-004X","type":"print"},{"value":"2090-0058","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}