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The pathogenesis of osteoporosis in transplant recipients is complex and multifactorial which may be related to increased bone resorption, decreased bone formation, or both. Studies have shown that the preexisting underlying metabolic bone disorders and the use of immunosuppressive agents are the major risk factors for osteoporosis and fractures after organ transplantation. And rapid bone loss usually occurs in the first 6\u201312 months with a significant increase in fracture risk. This paper will provide an updated review on the possible pathogenesis of posttransplant osteoporosis and fractures, the natural history, and the current prevention and treatment strategies concerning different types of organ transplantation.<\/jats:p>","DOI":"10.1155\/2015\/413169","type":"journal-article","created":{"date-parts":[[2015,11,15]],"date-time":"2015-11-15T21:01:25Z","timestamp":1447621285000},"page":"1-10","source":"Crossref","is-referenced-by-count":32,"title":["Current Status of Research on Osteoporosis after Solid Organ Transplantation: Pathogenesis and Management"],"prefix":"10.1155","volume":"2015","author":[{"given":"Gong-bin","family":"Lan","sequence":"first","affiliation":[{"name":"Center of Organ Transplantation, The Second Xiangya Hospital of Central South University, Changsha 410011, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu-biao","family":"Xie","sequence":"additional","affiliation":[{"name":"Center of Organ Transplantation, The 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