{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,3]],"date-time":"2026-03-03T00:14:55Z","timestamp":1772496895345,"version":"3.50.1"},"reference-count":11,"publisher":"Wiley","issue":"1","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":["onlinelibrary.wiley.com"],"crossmark-restriction":true},"short-container-title":["The Scientific World Journal"],"published-print":{"date-parts":[[2015,1]]},"abstract":"<jats:p><jats:italic>Background<\/jats:italic>. Long regimens for the treatment of post\u2010kala\u2010azar dermal leishmaniasis (PKDL) result in noncompliance. A safe, effective, and acceptable regimen for the treatment of PKDL is still to be developed. Miltefosine has been found to be effective in  the treatment of Visceral Leishmaniasis (VL). Hence, its efficacy was tested in patients of PKDL. <jats:italic>Methods<\/jats:italic>. In this exploratory study, 33 patients with PKDL aged 10 years and above were administered miltefosine (50\u2009mg for those weighing &lt;25\u2009kg or 100\u2009mg in divided doses for those \u226525\u2009kg and 2.5\u2009mg per kg for children) for 12 weeks and followed up for one year to find out the efficacy. <jats:italic>Results<\/jats:italic>. Out of 33 patients, 3 patients withdrew consent. Treatment was stopped due to adverse effect in 1 patient. 28 (96.6%) got cured with complete disappearance of lesion while 1 patient (3.4%) failed treatment by protocol analysis. <jats:italic>Conclusion<\/jats:italic>. Miltefosine was found to be effective and safe in the treatment of PKDL.<\/jats:p>","DOI":"10.1155\/2015\/414378","type":"journal-article","created":{"date-parts":[[2015,1,5]],"date-time":"2015-01-05T21:43:12Z","timestamp":1420494192000},"update-policy":"https:\/\/doi.org\/10.1002\/crossmark_policy","source":"Crossref","is-referenced-by-count":34,"title":["Efficacy and Safety of Miltefosine in Treatment of Post\u2010Kala\u2010Azar Dermal Leishmaniasis"],"prefix":"10.1155","volume":"2015","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9988-582X","authenticated-orcid":false,"given":"Shyam","family":"Sundar","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Anup","family":"Singh","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jaya","family":"Chakravarty","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Madhukar","family":"Rai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","published-online":{"date-parts":[[2015,1]]},"reference":[{"key":"e_1_2_7_1_2","doi-asserted-by":"publisher","DOI":"10.1016\/s1473-3099(03)00517-6"},{"key":"e_1_2_7_2_2","doi-asserted-by":"publisher","DOI":"10.1016\/s0140-6736(98)04367-0"},{"key":"e_1_2_7_3_2","doi-asserted-by":"publisher","DOI":"10.1056\/nejmoa021556"},{"key":"e_1_2_7_4_2","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pntd.0000832"},{"key":"e_1_2_7_5_2","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.43.7.3038-3041.2005"},{"key":"e_1_2_7_6_2","volume-title":"Common Toxicity Criteria of the DCTD, NCI, NIH, DHHS. 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