{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T16:02:23Z","timestamp":1779206543854,"version":"3.51.4"},"reference-count":32,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"Impact of Aquaculture Drugs and Chemicals on Aquatic Ecology and Productivity Project (IADCAEPP)"},{"DOI":"10.13039\/501100008229","name":"Bangladesh Fisheries Research Institute","doi-asserted-by":"publisher","id":[{"id":"10.13039\/501100008229","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Toxicology"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Quinalphos (QP) is commonly used for pest control in the agricultural fields surrounding freshwater reservoirs. This study was conducted to evaluate the chronic toxicity of this pesticide on blood parameters and some organs of silver barb,<jats:italic>Barbonymus gonionotus<\/jats:italic>. Fish were exposed to two sublethal concentrations, 0.47\u2009ppm and 0.94\u2009ppm, of QP for a period of 28 days. All the blood parameters (red blood cell, hematocrit, and hemoglobin) and blood glucose except for white blood cells decreased with increasing concentration of toxicant and become significantly lower (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>) at higher concentration when compared with control. The derived hematological indices of mean corpuscular volume, mean corpuscular hemoglobin, and mean corpuscular hemoglobin concentration were equally altered compared to control. Histoarchitectural changes of liver and kidney were observed after exposure to the QP. Hypertrophy of hepatocytes, mild to severe necrosis, ruptured central vein, and vacuolation were observed in the liver of treated groups. Highly degenerated kidney tubules and hematopoietic tissue, degeneration of renal corpuscle, vacuolization, and necrosis were evident in the kidney of treated groups. In conclusion, chronic exposure to QP at sublethal concentrations induced hematological and histological alterations in silver barb and offers a simple tool to evaluate toxicity derived alterations.<\/jats:p>","DOI":"10.1155\/2015\/415984","type":"journal-article","created":{"date-parts":[[2015,10,8]],"date-time":"2015-10-08T17:10:18Z","timestamp":1444324218000},"page":"1-8","source":"Crossref","is-referenced-by-count":31,"title":["Alteration of Blood Parameters and Histoarchitecture of Liver and Kidney of Silver Barb after Chronic Exposure to Quinalphos"],"prefix":"10.1155","volume":"2015","author":[{"given":"Golam","family":"Mohammod Mostakim","sequence":"first","affiliation":[{"name":"Department of Fisheries Biology & Genetics, Bangladesh Agricultural University (BAU), Mymensingh 2202, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md. Mahiuddin","family":"Zahangir","sequence":"additional","affiliation":[{"name":"Department of Fisheries Biology & Genetics, Bangladesh Agricultural University (BAU), Mymensingh 2202, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mahbuba","family":"Monir Mishu","sequence":"additional","affiliation":[{"name":"Department of Fisheries Biology & Genetics, Bangladesh Agricultural University (BAU), Mymensingh 2202, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Md. Khalilur","family":"Rahman","sequence":"additional","affiliation":[{"name":"Freshwater Station, Bangladesh Fisheries Research Institute (BFRI), Mymensingh 2201, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"M. Sadiqul","family":"Islam","sequence":"additional","affiliation":[{"name":"Department of Fisheries Biology & Genetics, Bangladesh Agricultural University (BAU), Mymensingh 2202, Bangladesh"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1007\/s00128-007-9190-y"},{"issue":"3","key":"2","first-page":"225","volume":"13","year":"2000","journal-title":"The Asian Fisheries Science Journal"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.11648\/j.ajls.20140204.14"},{"issue":"2","key":"4","first-page":"395","volume":"35","year":"2014","journal-title":"Journal of Environmental Biology"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.2298\/bah0904241c"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1111\/j.1095-8649.1973.tb04510.x"},{"key":"7","series-title":"US Fish and Wildlife Service. 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