{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,7]],"date-time":"2026-01-07T08:10:34Z","timestamp":1767773434786,"version":"build-2238731810"},"reference-count":80,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","award":["SAF2010-21249"],"award-info":[{"award-number":["SAF2010-21249"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","award":["2010-BMD2321"],"award-info":[{"award-number":["2010-BMD2321"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","award":["RETICS 06\/0016"],"award-info":[{"award-number":["RETICS 06\/0016"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","award":["PI 09\/0064"],"award-info":[{"award-number":["PI 09\/0064"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","award":["FIS 12\/01175"],"award-info":[{"award-number":["FIS 12\/01175"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003329","name":"Ministerio de Econom\u00eda y Competitividad","doi-asserted-by":"publisher","award":["PITN-GA-2011-287813"],"award-info":[{"award-number":["PITN-GA-2011-287813"]}],"id":[{"id":"10.13039\/501100003329","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012818","name":"Comunidad Aut\u00f3noma de Madrid","doi-asserted-by":"crossref","award":["SAF2010-21249"],"award-info":[{"award-number":["SAF2010-21249"]}],"id":[{"id":"10.13039\/100012818","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100012818","name":"Comunidad Aut\u00f3noma de Madrid","doi-asserted-by":"crossref","award":["2010-BMD2321"],"award-info":[{"award-number":["2010-BMD2321"]}],"id":[{"id":"10.13039\/100012818","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100012818","name":"Comunidad Aut\u00f3noma de Madrid","doi-asserted-by":"crossref","award":["RETICS 06\/0016"],"award-info":[{"award-number":["RETICS 06\/0016"]}],"id":[{"id":"10.13039\/100012818","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100012818","name":"Comunidad Aut\u00f3noma de Madrid","doi-asserted-by":"crossref","award":["PI 09\/0064"],"award-info":[{"award-number":["PI 09\/0064"]}],"id":[{"id":"10.13039\/100012818","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100012818","name":"Comunidad Aut\u00f3noma de Madrid","doi-asserted-by":"crossref","award":["FIS 12\/01175"],"award-info":[{"award-number":["FIS 12\/01175"]}],"id":[{"id":"10.13039\/100012818","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100012818","name":"Comunidad Aut\u00f3noma de Madrid","doi-asserted-by":"crossref","award":["PITN-GA-2011-287813"],"award-info":[{"award-number":["PITN-GA-2011-287813"]}],"id":[{"id":"10.13039\/100012818","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Fondo de Investigaciones Santitarias","award":["SAF2010-21249"],"award-info":[{"award-number":["SAF2010-21249"]}]},{"name":"Fondo de Investigaciones Santitarias","award":["2010-BMD2321"],"award-info":[{"award-number":["2010-BMD2321"]}]},{"name":"Fondo de Investigaciones Santitarias","award":["RETICS 06\/0016"],"award-info":[{"award-number":["RETICS 06\/0016"]}]},{"name":"Fondo de Investigaciones Santitarias","award":["PI 09\/0064"],"award-info":[{"award-number":["PI 09\/0064"]}]},{"name":"Fondo de Investigaciones Santitarias","award":["FIS 12\/01175"],"award-info":[{"award-number":["FIS 12\/01175"]}]},{"name":"Fondo de Investigaciones Santitarias","award":["PITN-GA-2011-287813"],"award-info":[{"award-number":["PITN-GA-2011-287813"]}]},{"name":"Fondo de Investigaciones Santitarias","award":["SAF2010-21249"],"award-info":[{"award-number":["SAF2010-21249"]}]},{"name":"Fondo de Investigaciones Santitarias","award":["2010-BMD2321"],"award-info":[{"award-number":["2010-BMD2321"]}]},{"name":"Fondo de Investigaciones Santitarias","award":["RETICS 06\/0016"],"award-info":[{"award-number":["RETICS 06\/0016"]}]},{"name":"Fondo de Investigaciones Santitarias","award":["PI 09\/0064"],"award-info":[{"award-number":["PI 09\/0064"]}]},{"name":"Fondo de Investigaciones Santitarias","award":["FIS 12\/01175"],"award-info":[{"award-number":["FIS 12\/01175"]}]},{"name":"Fondo de Investigaciones Santitarias","award":["PITN-GA-2011-287813"],"award-info":[{"award-number":["PITN-GA-2011-287813"]}]},{"name":"Fondo de Investigaciones Santitarias","award":["SAF2010-21249"],"award-info":[{"award-number":["SAF2010-21249"]}]},{"name":"Fondo de Investigaciones Santitarias","award":["2010-BMD2321"],"award-info":[{"award-number":["2010-BMD2321"]}]},{"name":"Fondo de Investigaciones Santitarias","award":["RETICS 06\/0016"],"award-info":[{"award-number":["RETICS 06\/0016"]}]},{"name":"Fondo de Investigaciones Santitarias","award":["PI 09\/0064"],"award-info":[{"award-number":["PI 09\/0064"]}]},{"name":"Fondo de Investigaciones Santitarias","award":["FIS 12\/01175"],"award-info":[{"award-number":["FIS 12\/01175"]}]},{"name":"Fondo de Investigaciones Santitarias","award":["PITN-GA-2011-287813"],"award-info":[{"award-number":["PITN-GA-2011-287813"]}]},{"DOI":"10.13039\/501100004963","name":"Seventh Framework Programme","doi-asserted-by":"publisher","award":["SAF2010-21249"],"award-info":[{"award-number":["SAF2010-21249"]}],"id":[{"id":"10.13039\/501100004963","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004963","name":"Seventh Framework Programme","doi-asserted-by":"publisher","award":["2010-BMD2321"],"award-info":[{"award-number":["2010-BMD2321"]}],"id":[{"id":"10.13039\/501100004963","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004963","name":"Seventh Framework Programme","doi-asserted-by":"publisher","award":["RETICS 06\/0016"],"award-info":[{"award-number":["RETICS 06\/0016"]}],"id":[{"id":"10.13039\/501100004963","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004963","name":"Seventh Framework Programme","doi-asserted-by":"publisher","award":["PI 09\/0064"],"award-info":[{"award-number":["PI 09\/0064"]}],"id":[{"id":"10.13039\/501100004963","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004963","name":"Seventh Framework Programme","doi-asserted-by":"publisher","award":["FIS 12\/01175"],"award-info":[{"award-number":["FIS 12\/01175"]}],"id":[{"id":"10.13039\/501100004963","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100004963","name":"Seventh Framework Programme","doi-asserted-by":"publisher","award":["PITN-GA-2011-287813"],"award-info":[{"award-number":["PITN-GA-2011-287813"]}],"id":[{"id":"10.13039\/501100004963","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>Fibrosis is a general complication in many diseases. It is the main complication during peritoneal dialysis (PD) treatment, a therapy for renal failure disease. Local inflammation and mesothelial to mesenchymal transition (MMT) are well known key phenomena in peritoneal damage during PD. New data suggest that, in the peritoneal cavity, inflammatory changes may be regulated at least in part by a delicate balance between T helper 17 and regulatory T cells. This paper briefly reviews the implication of the Th17\/Treg-axis in fibrotic diseases. Moreover, it compares current evidences described in PD animal experimental models, indicating a loss of Th17\/Treg balance (Th17 predominance) leading to peritoneal damage during PD. In addition, considering the new clinical and animal experimental data, new therapeutic strategies to reduce the Th17 response and increase the regulatory T response are proposed. Thus, future goals should be to develop new clinical biomarkers to reverse this immune misbalance and reduce peritoneal fibrosis in PD.<\/jats:p>","DOI":"10.1155\/2015\/416480","type":"journal-article","created":{"date-parts":[[2015,5,3]],"date-time":"2015-05-03T17:04:18Z","timestamp":1430672658000},"page":"1-9","source":"Crossref","is-referenced-by-count":17,"title":["T Helper 17\/Regulatory T Cell Balance and Experimental Models of Peritoneal Dialysis-Induced Damage"],"prefix":"10.1155","volume":"2015","author":[{"given":"Georgios","family":"Liappas","sequence":"first","affiliation":[{"name":"Department of Immunology, Centro de Biolog\u00eda Molecular Severo Ochoa (CBM), Consejo Superior de Investigaciones Cient\u00edficas (CSIC), 28049 Madrid, Spain"},{"name":"Department of Nephrology, Instituto de Investigaci\u00f3n del Hospital Universitario La Paz (IdiPAZ), 28046 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Guadalupe Tirma","family":"G\u00f3nzalez-Mateo","sequence":"additional","affiliation":[{"name":"Department of Immunology, Centro de Biolog\u00eda Molecular Severo Ochoa (CBM), Consejo Superior de Investigaciones Cient\u00edficas (CSIC), 28049 Madrid, Spain"},{"name":"Department of Nephrology, Instituto de Investigaci\u00f3n del Hospital Universitario La Paz (IdiPAZ), 28046 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pedro","family":"Majano","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology, Instituto de La Princesa (IP), 28006 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jos\u00e9 Antonio","family":"S\u00e1nchez- Tomero","sequence":"additional","affiliation":[{"name":"Nephrology Service, Hospital Universitario de La Princesa (IP), 28006 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Ruiz-Ortega","sequence":"additional","affiliation":[{"name":"Laboratory of Cellular Biology and Rare Diseases, Fundaci\u00f3n Jim\u00e9nez D\u00edaz, Universidad Aut\u00f3noma de Madrid (UAM), 28040 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6348-1505","authenticated-orcid":true,"given":"Raquel","family":"Rodrigues D\u00edez","sequence":"additional","affiliation":[{"name":"Laboratory of Cellular Biology and Rare Diseases, Fundaci\u00f3n Jim\u00e9nez D\u00edaz, Universidad Aut\u00f3noma de Madrid (UAM), 28040 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pilar","family":"Mart\u00edn","sequence":"additional","affiliation":[{"name":"Department of Molecular and Vascular Inflammation, Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Raquel","family":"Sanchez-D\u00edaz","sequence":"additional","affiliation":[{"name":"Department of Molecular and Vascular Inflammation, Centro Nacional de Investigaciones Cardiovasculares (CNIC), 28029 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Rafael","family":"Selgas","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Instituto de Investigaci\u00f3n del Hospital Universitario La Paz (IdiPAZ), 28046 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Manuel","family":"L\u00f3pez-Cabrera","sequence":"additional","affiliation":[{"name":"Department of Immunology, Centro de Biolog\u00eda Molecular Severo Ochoa (CBM), Consejo Superior de Investigaciones Cient\u00edficas (CSIC), 28049 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Abelardo","family":"Aguilera Peralta","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology, Instituto de La Princesa (IP), 28006 Madrid, Spain"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"issue":"2","key":"1","doi-asserted-by":"crossref","first-page":"470","DOI":"10.1681\/ASN.V132470","volume":"13","year":"2002","journal-title":"Journal of the American Society of Nephrology"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1038\/ki.1994.163"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.1999.00264.x"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcmed.2013.10.010"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0706309"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1007\/s10354-013-0216-2"},{"issue":"10","key":"7","doi-asserted-by":"crossref","first-page":"2176","DOI":"10.1681\/ASN.V7102176","volume":"7","year":"1996","journal-title":"Journal of the American Society of Nephrology"},{"issue":"6","key":"8","doi-asserted-by":"crossref","first-page":"517","DOI":"10.1177\/089686089901900605","volume":"19","year":"1999","journal-title":"Peritoneal Dialysis International"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2006111292"},{"key":"10","first-page":"90","volume":"131","year":"2001","journal-title":"Contributions to Nephrology"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1755.2001.07801.x"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2009070694"},{"issue":"3","key":"13","first-page":"S362","volume":"21","year":"2001","journal-title":"Peritoneal Dialysis International"},{"issue":"2","key":"14","doi-asserted-by":"crossref","first-page":"88","DOI":"10.1177\/089686089301300201","volume":"13","year":"1993","journal-title":"Peritoneal Dialysis International"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1016\/s0272-6386(99)70012-0"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/s0272-6386(12)80814-6"},{"issue":"4","key":"17","doi-asserted-by":"crossref","first-page":"327","DOI":"10.1177\/089686080402400407","volume":"24","year":"2004","journal-title":"Peritoneal Dialysis International"},{"issue":"2","key":"18","doi-asserted-by":"crossref","first-page":"227","DOI":"10.1177\/089686080902900218","volume":"29","year":"2009","journal-title":"Peritoneal Dialysis International"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1681\/asn.2008020211"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1081\/JDI-200037156"},{"issue":"4","key":"21","doi-asserted-by":"crossref","first-page":"438","DOI":"10.1177\/089686080602600407","volume":"26","year":"2006","journal-title":"Peritoneal Dialysis International"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.iy.07.040189.001045"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1159\/000046070"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/s0272-6386(96)90364-9"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2005.05.008"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.00456-10"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1038\/nature04753"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.02.021"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1155\/2012\/819467"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2006.07.035"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.179.7.4313"},{"key":"32","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C600321200"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1038\/nature06878"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1038\/ni1428"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20061852"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2006.01.001"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1038\/nature04754"},{"issue":"7","key":"38","doi-asserted-by":"crossref","first-page":"2178","DOI":"10.1002\/(SICI)1521-4141(199807)28:07<2178::AID-IMMU2178>3.0.CO;2-D","volume":"28","year":"1998","journal-title":"European Journal of Immunology"},{"issue":"12","key":"39","doi-asserted-by":"crossref","first-page":"6480","DOI":"10.4049\/jimmunol.161.12.6480","volume":"161","year":"1998","journal-title":"Journal of Immunology"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1016\/j.jneuroim.2007.09.009"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1254\/jphs.fmj05003x4"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.2741\/2341"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.1002\/path.2277"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1203013"},{"key":"45","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2013.01.015"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.182.1.692"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2010.080834"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1004081"},{"key":"49","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2011.594"},{"key":"50","doi-asserted-by":"publisher","DOI":"10.1002\/hep.22680"},{"key":"51","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2012.05.004"},{"key":"52","doi-asserted-by":"publisher","DOI":"10.1002\/hep.23273"},{"key":"53","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/dxs056"},{"key":"54","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.110.952820"},{"key":"55","doi-asserted-by":"publisher","DOI":"10.1681\/asn.2010050536"},{"key":"56","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2010.102"},{"key":"57","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2009030337"},{"key":"58","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2013.67"},{"key":"59","doi-asserted-by":"publisher","DOI":"10.1172\/jci38702"},{"key":"60","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2011.03529.x"},{"key":"61","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2008.11.004"},{"key":"62","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0015404"},{"key":"63","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0074955"},{"key":"64","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2014.00080"},{"key":"65","doi-asserted-by":"publisher","DOI":"10.1111\/exd.12368"},{"key":"66","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcma.2011.01.002"},{"key":"67","first-page":"53","volume":"60","year":"2007","journal-title":"Medicinski Pregled"},{"key":"68","doi-asserted-by":"publisher","DOI":"10.1155\/2013\/263285"},{"key":"69","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa020809"},{"issue":"8","key":"70","first-page":"1481","volume":"6","year":"2013","journal-title":"International Journal of Clinical and Experimental Pathology"},{"key":"71","doi-asserted-by":"publisher","DOI":"10.1038\/ki.2014.33"},{"key":"72","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfp005"},{"key":"73","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2010.111"},{"key":"74","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1102241"},{"key":"75","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0108477"},{"key":"76","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/dxr111"},{"issue":"2","key":"77","doi-asserted-by":"crossref","first-page":"164","DOI":"10.1177\/039139880502800213","volume":"28","year":"2005","journal-title":"International Journal of Artificial Organs"},{"key":"78","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/549101"},{"key":"79","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20082771"},{"key":"80","doi-asserted-by":"publisher","DOI":"10.5772\/56598"}],"updated-by":[{"DOI":"10.1155\/2017\/6130208","type":"corrigendum","label":"Corrigendum","source":"publisher","updated":{"date-parts":[[2017,2,8]],"date-time":"2017-02-08T00:00:00Z","timestamp":1486512000000}}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/416480.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/416480.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/416480.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,8,9]],"date-time":"2023-08-09T21:19:34Z","timestamp":1691615974000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/bmri\/2015\/416480\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":80,"alternative-id":["416480","416480"],"URL":"https:\/\/doi.org\/10.1155\/2015\/416480","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}