{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,22]],"date-time":"2025-10-22T17:59:28Z","timestamp":1761155968580},"reference-count":25,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"funder":[{"name":"Ju\u00e1rez University of Durango State"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>The magnitude of<jats:italic>Leptospira<\/jats:italic>exposure in rural Mexico is largely unknown. We sought to determine the seroprevalence of<jats:italic>Leptospira<\/jats:italic>IgG antibodies in adults in rural Durango, Mexico, and to determine the sociodemographic, behavioral, and housing characteristics of the subjects associated with<jats:italic>Leptospira<\/jats:italic>seropositivity. We performed a cross-sectional study in 282 adults living in rural Durango, Mexico. Sera from participants were analyzed for<jats:italic>Leptospira<\/jats:italic>IgG antibodies using a commercially available enzyme immunoassay. Seroprevalence association with the characteristics of the subjects was analyzed by bivariate and multivariate analyses. Of the 282 rural subjects (42.91 \u00b1 17.53 years old) studied, 44 (15.6%) had anti-<jats:italic>Leptospira<\/jats:italic>IgG antibodies. Seropositivity to<jats:italic>Leptospira<\/jats:italic>was not associated with gender, educational level, employment, socioeconomic status, contact with animals or soil, or type of floors at home. In contrast, multivariate analysis showed that<jats:italic>Leptospira<\/jats:italic>exposure was associated with national trips (OR = 2.09; 95% CI: 1.05\u20134.16;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.03<\/mml:mn><\/mml:math>) and poor education of the head of the family (OR = 2.96; 95% CI: 1.51\u20135.78;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>P<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>0.001<\/mml:mn><\/mml:math>). We demonstrated serological evidence of<jats:italic>Leptospira<\/jats:italic>exposure in adults in rural northern Mexico. The contributing factors associated with<jats:italic>Leptospira<\/jats:italic>exposure found in the present study may be useful for optimal planning of preventive measures against<jats:italic>Leptospira<\/jats:italic>infection.<\/jats:p>","DOI":"10.1155\/2015\/460578","type":"journal-article","created":{"date-parts":[[2015,7,9]],"date-time":"2015-07-09T23:26:37Z","timestamp":1436484397000},"page":"1-5","source":"Crossref","is-referenced-by-count":11,"title":["Seroepidemiology of<i>Leptospira<\/i>Exposure in General Population in Rural Durango, Mexico"],"prefix":"10.1155","volume":"2015","author":[{"given":"Cosme","family":"Alvarado-Esquivel","sequence":"first","affiliation":[{"name":"Biomedical Research Laboratory, Faculty of Medicine and Nutrition, Ju\u00e1rez University of Durango State, 34000 Durango, DGO, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Luis Francisco","family":"S\u00e1nchez-Anguiano","sequence":"additional","affiliation":[{"name":"Institute for Scientific Research \u201cDr. Roberto Rivera Damm\u201d, Ju\u00e1rez University of Durango State, 34000 Durango, DGO, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jes\u00fas","family":"Hern\u00e1ndez-Tinoco","sequence":"additional","affiliation":[{"name":"Institute for Scientific Research \u201cDr. Roberto Rivera Damm\u201d, Ju\u00e1rez University of Durango State, 34000 Durango, DGO, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.3390\/pathogens3020280"},{"issue":"4","key":"2","first-page":"589","volume":"96","year":"2014","journal-title":"Nihon Saikingaku Zasshi"},{"issue":"1358","key":"3","first-page":"20","volume":"125","year":"2012","journal-title":"New Zealand Medical 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