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The aim of this study is researching the role of the Regulatory T cell (Treg)\/T helper cell-17 (Th17) cell ratio imbalance in the pathogenesis of autoimmune hepatitis (AIH) and the use of the \u201cBu Xu Hua Yu\u201d recipe in the treatment of AIH.<jats:italic>Materials and Methods<\/jats:italic>. Sixty adult male C57\/BL6 mice were divided into six different groups.<jats:italic>\u03b1<\/jats:italic>-Galcer was injected abdominally for production of the animal models. Liver function tests, histological examinations, liver tissue Regulatory T cell, and T helper cell-17 levels tests were carried out. TGF-<jats:italic>\u03b2<\/jats:italic>1, IL-10, IL-17, and expression of mRNA and protein levels of Foxp3 and ROR-<jats:italic>\u03b3<\/jats:italic>t were also assessed.<jats:italic>Results<\/jats:italic>. Bu Xu Hua Yu method increased the levels of Regulatory T cell, IL-10, and the expression of Foxp3 (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>) in mice liver tissues. Furthermore, there were decreases in the levels of T helper cell-17, IL-17, and expression of ROR<jats:italic>\u03b3<\/jats:italic>t mRNA and protein (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>). The ratio of Treg\/Th17 was increased (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>P<\/mml:mi><mml:mo>&lt;<\/mml:mo><mml:mn>0.05<\/mml:mn><\/mml:math>).<jats:italic>Conclusion<\/jats:italic>. Mice with AIH have a Treg\/Th17 ratio imbalance. Bu Xu Hua Yu method was able to restore the cellular balance of Treg\/Th17 through the regulation of the expression of ROR<jats:italic>\u03b3<\/jats:italic>t and Foxp3 and can play an important role in the treatment of AIH.<\/jats:p>","DOI":"10.1155\/2015\/461294","type":"journal-article","created":{"date-parts":[[2015,4,21]],"date-time":"2015-04-21T17:08:34Z","timestamp":1429636114000},"page":"1-14","source":"Crossref","is-referenced-by-count":2,"title":["Chinese Medicine Bu Xu Hua Yu Recipe for the Regulation of Treg\/Th17 Ratio Imbalance in Autoimmune Hepatitis"],"prefix":"10.1155","volume":"2015","author":[{"given":"Lei","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Hepatology, Shanghai University of Traditional Chinese Medicine, Longhua Hospital, No. 725 South Wan Ping Road, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huihui","family":"Du","sequence":"additional","affiliation":[{"name":"Department of Hepatology, Shanghai University of Traditional Chinese Medicine, Longhua Hospital, No. 725 South Wan Ping Road, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibo","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Hepatology, Shanghai University of Traditional Chinese Medicine, Longhua Hospital, No. 725 South Wan Ping Road, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingtai","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Hepatology, Shanghai University of Traditional Chinese Medicine, Longhua Hospital, No. 725 South Wan Ping Road, Shanghai, China"},{"name":"Shanghai University of Traditional Chinese Medicine, Shuguang Hospital, Shanghai, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiong","family":"Ma","sequence":"additional","affiliation":[{"name":"Department of Hepatology, Shanghai University of Traditional Chinese Medicine, Longhua 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