{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,8,29]],"date-time":"2025-08-29T10:30:34Z","timestamp":1756463434275},"reference-count":9,"publisher":"Hindawi Limited","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Case Reports in Medicine"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p><jats:italic>Context<\/jats:italic>.<jats:italic>Clostridium perfringens<\/jats:italic>septicemia is often associated with translocation from the gastrointestinal or gastrourinary tract and occurs in patients who have malignancy or are immunocompromised.<jats:italic>Clostridium perfringens<\/jats:italic>septicemia is usually fatal without early identification, source control, and antibiotics.<jats:italic>Case<\/jats:italic>. We present a case of a 65-year-old female with<jats:italic>Clostridium perfringens<\/jats:italic>septicemia secondary to emphysematous cholecystitis, with progression to hepatic abscesses.<jats:italic>Conclusion<\/jats:italic>. Septicemia secondary to<jats:italic>Clostridium perfringens<\/jats:italic>is generally fatal if not detected early. Source control with surgery or percutaneous drainage and early antibiotic therapy is imperative. Hyperbaric oxygen therapy may reduce mortality. Clinicians caring for patients with sepsis and intravascular hemolysis must have<jats:italic>Clostridium perfringens<\/jats:italic>septicemia on their differential diagnosis with a low threshold for starting antibiotics and pursuing source of infection.<\/jats:p>","DOI":"10.1155\/2015\/523402","type":"journal-article","created":{"date-parts":[[2015,7,1]],"date-time":"2015-07-01T17:18:33Z","timestamp":1435771113000},"page":"1-3","source":"Crossref","is-referenced-by-count":10,"title":["Intravascular Hemolysis and Septicemia due to<i>Clostridium perfringens<\/i>Emphysematous Cholecystitis and Hepatic Abscesses"],"prefix":"10.1155","volume":"2015","author":[{"given":"Justin","family":"Cochrane","sequence":"first","affiliation":[{"name":"Internal Medicine Residency of Spokane, University of Washington Medical School, Spokane, WA 99204, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Lacie","family":"Bland","sequence":"additional","affiliation":[{"name":"Internal Medicine Residency of Spokane, University of Washington Medical School, Spokane, WA 99204, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mary","family":"Noble","sequence":"additional","affiliation":[{"name":"Internal Medicine Residency of Spokane, University of Washington Medical School, Spokane, WA 99204, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"98","reference":[{"issue":"10","key":"1","doi-asserted-by":"crossref","first-page":"2379","DOI":"10.1111\/j.1572-0241.2006.00856.x","volume":"101","year":"2006","journal-title":"The American Journal of Gastroenterology"},{"key":"2","doi-asserted-by":"publisher","DOI":"10.1177\/0885066613498043"},{"issue":"5","key":"3","doi-asserted-by":"crossref","first-page":"942","DOI":"10.1177\/0310057X1003800522","volume":"38","year":"2010","journal-title":"Anaesthesia and Intensive Care"},{"key":"4","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmii.2011.12.007"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.4254\/wjh.v4.i8.252"},{"issue":"9","key":"6","first-page":"343","volume":"68","year":"2010","journal-title":"Netherlands Journal of Medicine"},{"issue":"1","key":"7","first-page":"569","volume":"8","year":"2015","journal-title":"International Journal of Clinical & Experimental Pathology"},{"key":"8","volume":"1","year":"2002"},{"key":"9","volume":"1","year":"2012"}],"container-title":["Case Reports in Medicine"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2015\/523402.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2015\/523402.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/crim\/2015\/523402.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,27]],"date-time":"2019-08-27T18:23:56Z","timestamp":1566930236000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/crim\/2015\/523402\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":9,"alternative-id":["523402","523402"],"URL":"https:\/\/doi.org\/10.1155\/2015\/523402","relation":{},"ISSN":["1687-9627","1687-9635"],"issn-type":[{"value":"1687-9627","type":"print"},{"value":"1687-9635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}