{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,8]],"date-time":"2026-01-08T08:36:33Z","timestamp":1767861393290,"version":"3.49.0"},"reference-count":48,"publisher":"Wiley","license":[{"start":{"date-parts":[[2015,1,1]],"date-time":"2015-01-01T00:00:00Z","timestamp":1420070400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/3.0\/"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["BioMed Research International"],"published-print":{"date-parts":[[2015]]},"abstract":"<jats:p>The aim of the study was to compare sRAGE and esRAGE plasma levels in pregnant women with (A) threatened premature labor (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M1\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>41<\/mml:mn><\/mml:math>), (B) preterm premature rupture of membranes (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M2\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>49<\/mml:mn><\/mml:math>), and (C) preterm rupture of membranes at term (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M3\"><mml:mi>n<\/mml:mi><mml:mo>=<\/mml:mo><mml:mn>48<\/mml:mn><\/mml:math>). The relationship between these and classic intrauterine infection markers and the latent time from symptoms up to delivery depending on RAGE\u2019s concentration were investigated. In groups A and B, a positive correlation was found between plasma sRAGE and latent time (<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M4\"><mml:mrow><mml:mi>r<\/mml:mi><\/mml:mrow><\/mml:math>= 0,422;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M5\"><mml:mrow><mml:mi>p<\/mml:mi><\/mml:mrow><\/mml:math>= 0,001;<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M6\"><mml:mrow><mml:mi>r<\/mml:mi><\/mml:mrow><\/mml:math>= 0,413,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M7\"><mml:mrow><mml:mi>p<\/mml:mi><\/mml:mrow><\/mml:math>= 0,004, resp.). High prognostic values were found in both groups for plasma sRAGE concentration and the latent time from symptoms up to delivery. Groups B and C presented higher levels of esRAGE than group A (526,315\u2009\u00b1\u2009129,453\u2009pg\/mL and 576,212\u2009\u00b1\u2009136,237\u2009pg\/mL versus 485,918\u2009\u00b1\u2009133,127\u2009pg\/mL,<mml:math xmlns:mml=\"http:\/\/www.w3.org\/1998\/Math\/MathML\" id=\"M8\"><mml:mi>p<\/mml:mi><mml:mo>&lt;<\/mml:mo><\/mml:math>0,05). The conclusion is that sRAGE concentration can be a favorable prognostic factor in the presence of symptoms of threatened premature labor. Higher esRAGE plasma level in case of the rupture of membranes in mature and premature pregnancy suggests its participation in fetal membranes destruction.<\/jats:p>","DOI":"10.1155\/2015\/568042","type":"journal-article","created":{"date-parts":[[2015,8,27]],"date-time":"2015-08-27T17:32:44Z","timestamp":1440696764000},"page":"1-10","source":"Crossref","is-referenced-by-count":10,"title":["Soluble and Endogenous Secretory Receptors for Advanced Glycation End Products in Threatened Preterm Labor and Preterm Premature Rupture of Fetal Membranes"],"prefix":"10.1155","volume":"2015","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9294-1005","authenticated-orcid":true,"given":"Rafa\u0142","family":"Rzepka","sequence":"first","affiliation":[{"name":"Department of Obstetrics and Gynecology, Pomeranian Medical University, 70-204 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Barbara","family":"Do\u0142egowska","sequence":"additional","affiliation":[{"name":"Department of Laboratory Diagnostics and Molecular Medicine, Pomeranian Medical University, 70-204 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4751-3896","authenticated-orcid":true,"given":"Aleksandra","family":"Rajewska","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Pomeranian Medical University, 70-204 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sebastian","family":"Kwiatkowski","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Pomeranian Medical University, 70-204 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daria","family":"Sa\u0142ata","sequence":"additional","affiliation":[{"name":"Department of Laboratory Diagnostics and Molecular Medicine, Pomeranian Medical University, 70-204 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Marta","family":"Budkowska","sequence":"additional","affiliation":[{"name":"Department of Laboratory Diagnostics and Molecular Medicine, Pomeranian Medical University, 70-204 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Leszek","family":"Doma\u0144ski","sequence":"additional","affiliation":[{"name":"Department of Nephrology, Transplantology and Internal Medicine, Pomeranian Medical University, 70-204 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wioletta","family":"Miko\u0142ajek-Bedner","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Pomeranian Medical University, 70-204 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrzej","family":"Torb\u00e9","sequence":"additional","affiliation":[{"name":"Department of Obstetrics and Gynecology, Pomeranian Medical University, 70-204 Szczecin, Poland"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"311","reference":[{"key":"1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(08)60074-4"},{"issue":"6198","key":"2","doi-asserted-by":"crossref","first-page":"760","DOI":"10.1126\/science.1251816","volume":"345","year":"2014","journal-title":"Science"},{"key":"3","doi-asserted-by":"publisher","DOI":"10.1111\/j.1749-6632.2010.05684.x"},{"issue":"9","key":"4","first-page":"678","volume":"80","year":"2009","journal-title":"Ginekologia Polska"},{"key":"5","doi-asserted-by":"publisher","DOI":"10.1111\/aji.12189"},{"key":"6","doi-asserted-by":"publisher","DOI":"10.1080\/13547500903045583"},{"issue":"2","key":"7","first-page":"125","volume":"210","year":"2014","journal-title":"American Journal of Obstetrics & Gynecology"},{"issue":"6","key":"8","first-page":"537","volume":"19","year":"2014","journal-title":"Journal of Research in Medical Sciences"},{"key":"9","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2014.961417"},{"key":"10","doi-asserted-by":"publisher","DOI":"10.1177\/1933719110363618"},{"key":"11","doi-asserted-by":"publisher","DOI":"10.1210\/en.2013-1304"},{"key":"12","doi-asserted-by":"publisher","DOI":"10.1007\/978-0-387-72005-0_19"},{"key":"13","doi-asserted-by":"publisher","DOI":"10.1038\/sj.embor.7400759"},{"key":"14","doi-asserted-by":"publisher","DOI":"10.1111\/j.1432-1033.1973.tb03026.x"},{"key":"15","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111204200"},{"key":"16","doi-asserted-by":"publisher","DOI":"10.1016\/s0167-4889(00)00087-2"},{"key":"17","doi-asserted-by":"publisher","DOI":"10.1155\/2010\/490406"},{"issue":"5","key":"18","doi-asserted-by":"crossref","first-page":"E685","DOI":"10.1152\/ajpendo.2001.280.5.E685","volume":"280","year":"2001","journal-title":"The American Journal of Physiology\u2014Endocrinology and Metabolism"},{"key":"19","doi-asserted-by":"publisher","DOI":"10.1042\/BST20130156"},{"key":"20","doi-asserted-by":"publisher","DOI":"10.1172\/jci118175"},{"key":"21","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2013.01.016"},{"key":"22","doi-asserted-by":"publisher","DOI":"10.3390\/ijms141019891"},{"key":"23","doi-asserted-by":"publisher","DOI":"10.1016\/j.diabet.2008.04.003"},{"key":"24","doi-asserted-by":"publisher","DOI":"10.1016\/j.atherosclerosis.2012.10.050"},{"key":"25","doi-asserted-by":"publisher","DOI":"10.1002\/hep.26264"},{"key":"26","doi-asserted-by":"publisher","DOI":"10.1196\/annals.1433.056"},{"key":"27","doi-asserted-by":"publisher","DOI":"10.1161\/hc0702.104183"},{"key":"28","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2005.08.006"},{"key":"29","doi-asserted-by":"publisher","DOI":"10.1006\/geno.1994.1517"},{"key":"30","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2004.09.011"},{"key":"31","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.50.12.2792"},{"issue":"11","key":"32","first-page":"985","volume":"7","year":"2006","journal-title":"Current Opinion in Investigational Drugs"},{"key":"33","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.m409782200"},{"key":"34","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20021371"},{"key":"35","doi-asserted-by":"publisher","DOI":"10.1515\/jpm.2008.080"},{"key":"36","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinbiochem.2012.06.031"},{"key":"37","doi-asserted-by":"publisher","DOI":"10.1515\/jpm.2008.076"},{"key":"38","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/251451"},{"key":"40","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfu282"},{"key":"41","doi-asserted-by":"publisher","DOI":"10.1007\/s13277-014-2122-7"},{"key":"42","doi-asserted-by":"publisher","DOI":"10.1055\/s-0033-1363423"},{"key":"43","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2012.663825"},{"key":"44","doi-asserted-by":"publisher","DOI":"10.1097\/GRF.0b013e318217ee18"},{"issue":"3","key":"45","year":"2010","journal-title":"Cochrane Database of Systematic Reviews"},{"key":"46","doi-asserted-by":"publisher","DOI":"10.1080\/14767050701227877"},{"key":"47","doi-asserted-by":"publisher","DOI":"10.1111\/j.0001-6349.2005.00747.x"},{"key":"48","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/874984"},{"key":"39","doi-asserted-by":"publisher","DOI":"10.3109\/14767058.2011.599083"}],"container-title":["BioMed Research International"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/568042.pdf","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/568042.xml","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"http:\/\/downloads.hindawi.com\/journals\/bmri\/2015\/568042.pdf","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,8,29]],"date-time":"2019-08-29T18:44:19Z","timestamp":1567104259000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.hindawi.com\/journals\/bmri\/2015\/568042\/"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015]]},"references-count":48,"alternative-id":["568042","568042"],"URL":"https:\/\/doi.org\/10.1155\/2015\/568042","relation":{},"ISSN":["2314-6133","2314-6141"],"issn-type":[{"value":"2314-6133","type":"print"},{"value":"2314-6141","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015]]}}}